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101
THE DEMOGRAPHIC PROFILE OF HIV-1 DRUG RESISTANCE PROTEASE/ REVERSE TRANSCRIPTASE (PR/RT) CASES IN MALAYSIA FROM 2020-2022
Published 2023-05-01“…Then it is analysed with reference to Stanford HIV Drug Resistance Database. Patients’ forms are screened for clinical profile and demographic distribution. …”
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102
Probe Capture Enrichment Methods for HIV and HCV Genome Sequencing and Drug Resistance Genotyping
Published 2022-06-01“…Over the years, sophisticated sequencing technologies such as next-generation sequencing (NGS) have emerged and been utilized to monitor the spread of HIV drug resistance (HIVDR), identify HIV drug resistance mutations, and characterize transmission dynamics. …”
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103
Use of a mutation-specific genotyping method to assess for HIV-1 drug resistance in antiretroviral-naïve HIV-1 Subtype C-infected patients in Botswana [version 2; peer review: 2 ap...
Published 2021-05-01“…The high costs of available HIV drug resistance assays prohibit their routine usage in resource-limited settings. …”
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104
Collaborative update of a rule-based expert system for HIV-1 genotypic resistance test interpretation
Published 2017“…</p> <h4>Conclusions</h4> <p>The HIVDB GRT-IS was updated through a collaborative process to reflect changes in HIV drug resistance knowledge, treatment guidelines, and expert opinion. …”
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105
Potential Anti-HIV Agents from Marine Resources: An Overview
Published 2010-11-01“…However, emergence of HIV drug resistance, side effects and the necessity for long-term anti-HIV treatment are the main reasons for failure of anti-HIV therapy. …”
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106
FIVE-YEAR EXPERIENCE OF HIGHLY ACTIVITY ANTIRETROVIRAL THERAPY IN CHILDREN WITH HIV-INFECTION
Published 2015-09-01“…For increase of therapy efficiency it is necessary lopinavir/ritonavir to include in HAART schemes, and also to carry out selection of preparations taking into account HIV drug resistance.…”
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107
Emergence of untreatable, multidrug-resistant HIV-1 in patients failing second-line therapy in Kenya
Published 2017“…We performed a countrywide assessment of HIV drug resistance among 123 patients with virological failure on second-line antiretroviral therapy (ART) in Kenya. …”
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108
HIV virologic response, patterns of drug resistance mutations and correlates among adolescents and young adults: A cross-sectional study in Tanzania
Published 2023-01-01“…<h4>Background</h4> The emergence of HIV drug resistance mutations (DRMs) is of significant threat to achieving viral suppression (VS) in the quest to achieve global elimination targets. …”
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109
HIV virologic response, patterns of drug resistance mutations and correlates among adolescents and young adults: A cross-sectional study in Tanzania.
Published 2023-01-01“…<h4>Background</h4>The emergence of HIV drug resistance mutations (DRMs) is of significant threat to achieving viral suppression (VS) in the quest to achieve global elimination targets. …”
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110
High prevalence of pre-treatment and acquired HIV-1 drug resistance mutations among non-citizens living with HIV in Botswana
Published 2024-02-01“…Viral RNA isolated from plasma samples were genotyped for HIV drug resistance (HIVDR) using Sanger sequencing. Major known HIV drug resistance mutations (DRMs) in the pol region were determined using the Stanford HIV Drug Resistance Database. …”
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111
Molecular epidemiology and reverse transcript ase (RT) and protease inhibitors (PR) resistance genotyping of human immunodeficiency virus (HIV) in Kelantan
Published 2012“…Genotyping Tool while ARV resistance mutations were analysed using Stanford HIV Drug Resistance Database.…”
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Monograph -
112
Characterisation of circulatiing HIV-1 subtypes and drug resistance-associated mutations in protease and reverse transcriptase genes among HIV-1 patients in Kelantan
Published 2015“…Meanwhile, according to Stanford HIV drug resistance database, 79.7% of patients currently receiving treatment carrying HIV-1 containing acquired RAMs against NRTI, NNRTI and PI. …”
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Thesis -
113
HIV-1C in-House RNA-Based Genotyping Assay for Detection of Drug Resistance Mutations in Samples with Low-Level Viral Loads
Published 2022-12-01“…We here assess the performance of an in-house HIV drug resistance genotyping assay using plasma for the detection of DRM at LLV.Methods: We used a total of 96 HIV plasma samples from the population-based Botswana Combination Prevention Project (BCPP). …”
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114
HIV protease resistance mutations in patients receiving second-line antiretroviral therapy in Libreville, Gabon
Published 2024-03-01“…This study aims to determine the profiles of HIV drug resistance mutations related to protease inhibitors in Gabon. …”
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115
Epidemiological characteristics of HIV transmission in southeastern China from 2015 to 2020 based on HIV molecular network
Published 2023-10-01“…The dominant HIV subtypes were CRF01_AE (41.7%) and CRF07_BC (38.3%) in 2015 and CRF07_BC (53. 3%) and CRF01_AE (29.1%) in 2020, and the prevalence of HIV drug resistance was 4.2% in 2015 and 5.3% in 2020. Sequences of CRF07_BC formed the largest HIV-1 transmission cluster at a genetic distance threshold of both 1.5 and 0.5%. …”
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116
The global burden of HIV-1 drug resistance in the past 20 years
Published 2018-05-01“…In this work, we queried two of the largest public HIV sequence repositories in the world—Los Alamos and Stanford HIVdb—to derive global prevalence, time trends and geodemographic predictors of HIV drug resistance. Different genotypic interpretation systems were used to ascertain resistance to reverse transcriptase and protease inhibitors. …”
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117
Molecular epidemiological analysis of HIV-1 in Kazakhstan in 2009-2013
Published 2015-08-01“…The data on low prevalence (3%) of HIV drug resistance mutations in native patients were obtained.…”
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118
Understanding patterns of HIV multi-drug resistance through models of temporal and spatial drug heterogeneity
Published 2021-09-01“…These therapies should prevent HIV drug resistance evolution, because one or more drugs suppress any partially resistant viruses. …”
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119
Virological and immunological effects of short-course antiretroviral therapy in primary HIV infection.
Published 2002“…Two of the 45 individuals had evidence of genotypic HIV drug resistance at baseline, and none developed new mutations following therapy. …”
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120
Virological and immunological effects of short-course antiretroviral therapy in primary HIV infection.
Published 2002“…Two of the 45 individuals had evidence of genotypic HIV drug resistance at baseline, and none developed new mutations following therapy. …”
Journal article