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Recommendations on data sharing in HIV drug resistance research.
Published 2023-09-01“… • Human immunodeficiency virus (HIV) drug resistance has implications for antiretroviral treatment strategies and for containing the HIV pandemic because the development of HIV drug resistance leads to the requirement for antiretroviral drugs that may be less effective, less well-tolerated, and more expensive than those used in first-line regimens…”
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Overview of the Analytes Applied in Genotypic HIV Drug Resistance Testing
Published 2022-06-01“…The close monitoring of HIV drug resistance using genotypic HIV drug resistance testing (HIVDRT) has become essential for effective HIV/AIDS management at both individual and population levels. …”
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Epidemic Characteristics of HIV Drug Resistance in Hefei, Anhui Province
Published 2022-07-01“…To study the characteristics of HIV pretreatment drug resistance (PDR) and acquired drug resistance (ADR) in Hefei, a cross-sectional survey was used to collect 816 samples from newly reported HIV infections from 2017 to 2020 and 127 samples from HIV infections with virological failure from 2018 to 2019 in Hefei. HIV drug resistance levels and drug resistance mutations were interpreted using the Stanford Drug Resistance Database. …”
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Strategies to overcome HIV drug resistance-current and future perspectives
Published 2023-02-01“…According to the latest WHO HIV Drug Resistance Report, the prevalence of acquired and transmitted HIV drug resistance in ART naive individuals has exponentially increased in the recent years, being an important obstacle in ending HIV-1 epidemic as a public health threat by 2030. …”
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Extracting causal relations on HIV drug resistance from literature
Published 2013“…Conclusions The proposed relation extraction and combination method has a good performance on extracting HIV drug resistance data. It can be used in large-scale relation extraction experiments. …”
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The effect of intrinsic stochasticity on transmitted HIV drug resistance patterns
Published 2010“…Estimates of transmitted HIV drug-resistance prevalence vary widely among and within epidemiological surveys. …”
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HIV drug resistance in low-income and middle-income countries
Published 2018“…After 15 years of global scale-up of antiretroviral therapy (ART), rising prevalence of HIV drug resistance in many low-income and middle-income countries (LMICs) poses a growing threat to the HIV response, with the potential to drive an increase in mortality, HIV incidence, and costs. …”
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The effect of intrinsic stochasticity on transmitted HIV drug resistance patterns.
Published 2010“…Estimates of transmitted HIV drug-resistance prevalence vary widely among and within epidemiological surveys. …”
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Point-of-Care Tests for HIV Drug Resistance Monitoring: Advances and Potentials
Published 2022-06-01“…Effective management of HIV drug resistance (HIVDR) supported by close resistance monitoring is essential in achieving the WHO 95-95-95 targets, aiming to end the AIDS epidemic by 2030. …”
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Is increasing pretreatment HIV drug resistance a real menace or minor detail?
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Current Research on HIV Drug Resistance—A Topical Collection with “<i>Pathogens</i>”
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Next-Generation Sequencing for HIV Drug Resistance Testing: Laboratory, Clinical, and Implementation Considerations
Published 2020-06-01Subjects: “…HIV drug resistance…”
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Are We Ready for NGS HIV Drug Resistance Testing? The Second “Winnipeg Consensus” Symposium
Published 2020-05-01Subjects: Get full text
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Current ART, determinants for virologic failure and implications for HIV drug resistance: an umbrella review
Published 2023-10-01“…The bulk of these studies concurred on several major factors contributing to HIV drug resistance and virological failure. Key among these were medication adherence, baseline and therapeutic CD4 levels, the presence of co-infections, and the advanced clinical stage of the infection. …”
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Affordable HIV drug-resistance testing for monitoring of antiretroviral therapy in sub-Saharan Africa.
Published 2016“…In this Personal View, we discuss the potential role of HIV drug resistance testing for population-based surveillance and individual patient management in sub-Saharan Africa. …”
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The evolving landscape of HIV drug resistance diagnostics for expanding testing in resource-limited settings
Published 2017“…Affordable technologies to monitor ART are needed to ensure long-term durability of limited available drug regimens. HIV drug resistance tests can complement existing strategies in optimizing clinical decision-making for patients with treatment failure, in addition to facilitating population-based surveillance of HIV drug resistance. …”
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