Associations of genetic polymorphisms of the vitamin D pathway with blood pressure in a Han Chinese population by Xiaoman Ye, Jian Jia, Ning Zhang, Haixia Ding, Yiyang Zhan

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Relationship between gut microbiota and lymphocyte subsets in Chinese Han patients with spinal cord injury by Rizhao Pang, Junyu Wang, Yisong Xiong, Jiancheng Liu, Xin Ma, Xiang Gou, Xin He, Chao Cheng, Wenchun Wang, Jinqi Zheng, Mengyuan Sun, Xingang Bai, Ling Bai, Anren Zhang

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Assessing the impact of novel risk loci on Alzheimer’s and Parkinson’s diseases in a Chinese Han cohort by Huimin Yan, Minglei Liu, Yuan Gao, Yuan Gao, Yuan Gao, Yuan Gao, Yanpeng Yuan, Yanpeng Yuan, Yanpeng Yuan, Yanpeng Yuan, Xiaojing Liu, Xiaojing Liu, Xiaojing Liu, Yangyang Wang, Yangyang Wang, Yangyang Wang, Lanjun Li, Lanjun Li, Qingzhi Wang, Yanlin Wang, Yanlin Wang, Yanlin Wang, Yanlin Wang, Changhe Shi, Changhe Shi, Yuming Xu, Yuming Xu, Yuming Xu, Yuming Xu, Jing Yang, Jing Yang, Jing Yang

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Whole Genome Analyses of Chinese Population and De Novo Assembly of A Northern Han Genome by Zhenglin Du, Liang Ma, Hongzhu Qu, Wei Chen, Bing Zhang, Xi Lu, Weibo Zhai, Xin Sheng, Yongqiao Sun, Wenjie Li, Meng Lei, Qiuhui Qi, Na Yuan, Shuo Shi, Jingyao Zeng, Jinyue Wang, Yadong Yang, Qi Liu, Yaqiang Hong, Lili Dong, Zhewen Zhang, Dong Zou, Yanqing Wang, Shuhui Song, Fan Liu, Xiangdong Fang, Hua Chen, Xin Liu, Jingfa Xiao, Changqing Zeng

“…To unravel the genetic mechanisms of disease and physiological traits, it requires comprehensive sequencing analysis of large sample size in Chinese populations. Here, we report the primary results of the Chinese Academy of Sciences Precision Medicine Initiative (CASPMI) project launched by the Chinese Academy of Sciences, including the de novo assembly of a northern Han reference genome (NH1.0) and whole genome analyses of 597 healthy people coming from most areas in China. …”
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TBX5 genetic variants and SCD-CAD susceptibility: insights from Chinese Han cohorts by Yukun Rui, Ju Zhou, Xiaoyuan Zhen, Jianhua Zhang, Shiquan Liu, Yuzhen Gao

“…This study systematically examined variants within the 500-bp region downstream of the TBX5 gene, focusing on their potential impact on susceptibility to SCD associated with coronary artery disease (SCD-CAD) in four different Chinese Han populations. Methods In a comprehensive case-control analysis, we explored the association between rs11278315 and SCD-CAD susceptibility using a cohort of 553 controls and 201 SCD-CAD cases. …”
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Hematological and inflammatory markers in Han Chinese patients with drug-free schizophrenia: relationship with symptom severity by Cheng Yang, Cheng Yang, Cheng Yang, Yinghan Tian, Yinghan Tian, Yinghan Tian, Xiaoxue Yang, Xiaoxue Yang, Xiaoxue Yang, Lewei Liu, Lewei Liu, Lewei Liu, Chen Ling, Chen Ling, Chen Ling, Lei Xia, Lei Xia, Huanzhong Liu, Huanzhong Liu

“…In this study, we aimed to examine the relationship between hematological and inflammatory markers with symptom severity in Han Chinese patients with drug-free schizophrenia.MethodsThis retrospective study was conducted at Chaohu Hospital of Anhui Medical University and data were extracted from the electronic medical record system over a 5-year period (May 2017 to April 2022), including participants’ general and clinical information as well as Brief Psychiatric Rating Scale (BPRS) scores and hematological parameters.ResultsA total of 2,899 patients with schizophrenia were identified through the initial search. …”
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Cross-Platform Application of DNA Methylation Age Estimation Model in Eastern Chinese Han Population by Zi-wei WANG, Cheng-tao LI, Xi-ling LIU

“…Objective To evaluate the forensic application value of an age estimation model based on DNA methylation in eastern Chinese Han population， and to provide a theoretical basis for exploring age estimation models suitable for different detection platforms. …”
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Association of PCSK1 rs6234 with obesity and related traits in a Chinese Han population. by Qibin Qi, Huaixing Li, Ruth J F Loos, Chen Liu, Frank B Hu, Hongyu Wu, Zhijie Yu, Xu Lin

“…We aimed to replicate this association in Chinese.Two PCSK1 variants rs6234 and rs6235 (in strong LD with each other, r(2) = 0.98) were genotyped in a population-based cohort of 3,210 Chinese Hans. …”
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Association between MMP2 gene polymorphisms and dilated cardiomyopathy in a Chinese Han population by Shiyang Li, Xiaobin Zeng, Shihai Wang, Xiaoshuang Xie, Jianjun Lan

“…Conclusions Our study suggested that MMP2 gene polymorphisms were associated with DCM susceptibility and prognosis in the Chinese Han population.…”
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The Mitochondrial tRNAPhe 625G>A Mutation in Three Han Chinese Families With Cholecystolithiasis by Lingling Hou, Cuifang Hu, Lili Ji, Qiongdan Wang, Min Liang, Min Liang

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Irisin as a predictor of bone metabolism in Han Chinese Young Men with pre-diabetic individuals by Junru Liu, Xing Wang, Dongmei Fan, Lina Sun, Weinan Zhang, Fuzai Yin, Bowei Liu

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Polymorphisms in CISH gene are associated with persistent hepatitis B virus infection in Han Chinese population. by Zhangyong Hu, Jinliang Yang, Yangping Wu, Guolian Xiong, Yali Wang, Jun Yang, Lan Deng

“…CONCLUSION: Two SNPs (rs414171 and rs2239751) in the CISH gene were associated with persistent HBV infection in Han Chinese population, but not with HBV progression.…”
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Association of HLA-DQB1 gene polymorphisms with outcomes of HBV infection in Chinese Han population by XL Zhu, T Du, LP Lu, XH Guo, JR Gao, CY Gou

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Corrigendum: Association between GSDMB gene polymorphism and cervical cancer in the Northeast Chinese Han population by Songxue Li, Xiaoying Li, Shuang Zhang, Yanan Feng, Tianshuang Jia, Manning Zhu, Lei Fang, Liping Gong, Shuang Dong, Xianchao Kong, Zhenzhen Wang, Litao Sun

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The association between interleukin‐1 polymorphisms and their protein expression in Chinese Han patients with breast cancer by Juan Wang, Yonggang Shi, Gaochao Wang, Shiliang Dong, Daoke Yang, Xiaoxiao Zuo

“…This fact and plethora of gene polymorphism data prompted us to investigate the relationship between IL‐1 polymorphisms and IL‐1 protein expression in Chinese Han BC patients. Method In total, 298 patients with BC and 287 healthy control women were studied. …”
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Common variants in GNL3 gene contributed the susceptibility of hand osteoarthritis in Han Chinese population by Xi Wang, Lin Xiao, Zhiyuan Wang, Liqiang Zhi, Qiang Li

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Mitochondrial tRNA Mutation and Regulation of the Adiponectin Pathway in Maternally Inherited Hypertension in Chinese Han by Jing Bai, Jing Bai, Qiang Ma, Yunfeng Lan, Yating Chen, Shanshan Ma, Jiaxin Li, Chuanbin Liu, Chuanbin Liu, Zihao Fu, Zihao Fu, Xu Lu, Xu Lu, Yun Huang, Yang Li

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Characterization of loss of chromosome Y in peripheral blood cells in male Han Chinese patients with schizophrenia by Lanrui Jiang, Mengyuan Song, Feng Song, Yuxiang Zhou, Hewen Yao, Gangqin Li, Haibo Luo

“…The logistic regression analysis implied that the risk of LOY increases by 0.058 and 0.057 per year according to age at onset and duration of disease, respectively (p onset = 0.013, p duration = 0.017). Conclusions In the Han Chinese population, the LOY percentage of the disease group was significantly different from that of the control group. …”
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Temporal relationship between sleep duration and obesity among Chinese Han people and ethnic minorities by Zhengxing Xu, Min Chen, Yuntong Yao, Lisha Yu, Peijing Yan, Huijie Cui, Ping Li, Jiaqiang Liao, Ben Zhang, Yuqin Yao, Zhenmi Liu, Xia Jiang, Tao Liu, Chenghan Xiao

“…Abstract Background No studies have assessed the association between sleep duration and obesity in Chinese ethnic minorities. Whether the relationship between sleep duration and obesity is different between Chinese Han people and Chinese ethnic minorities remains unclear. …”
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Association of SOX6 gene polymorphisms with Kashin-Beck disease risk in the Chinese Han population by He Na, Hong Aiwen, Zhao Kun, Zhang Zhefan, Wang Shengli, Jia Yaofei

“…In the case–control study, 735 unrelated Chinese Han individuals were enrolled. The four mutation sites of the SOX6 gene (rs4539287 G/A, rs3203295 C/A, rs7928675 C/A, and rs10832681 A/G) were screened and genotyped on the Agena MassARRAY platform. …”
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