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Genome-wide association study in a Chinese population identifies a susceptibility locus for type 2 diabetes at 7q32 near PAX4.
Published 2013“…METHODS: We performed a meta-analysis of three GWAS comprising 684 patients with type 2 diabetes and 955 controls of Southern Han Chinese descent. We followed up the top signals in two independent Southern Han Chinese cohorts (totalling 10,383 cases and 6,974 controls), and performed in silico replication in multiple populations. …”
Journal article -
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A 3' UTR SNP in COL18A1 is associated with susceptibility to HBV related hepatocellular carcinoma in Chinese: three independent case-control studies.
Published 2012-01-01“…CONCLUSION: These findings indicate that COL18A1 rs7499 may contribute to the risk of HCC in Han Chinese.…”
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New Archaeological Discoveries Based on Spatial Information Technology and Cultural Analysis: Taking the Study of the Spatial Relationship between Ancient Chinese Capitals and the...
Published 2022-07-01“…The capital of the Sui and Tang dynasties was specially aligned with the capital of the Western Han dynasty in space. These characteristics embody ancient Chinese Confucian cultural thoughts such as the “integration of yang and yin”, “harmony between nature and humans”, the “supremacy of emperors”, and the “use of numbers and shapes to convey meaning”.…”
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ORANG TIONGHOA, PERKEBUNAN GAMBIR, LADA DAN KONTESTASI DI TANJUNGPINANG ABAD KE-19
Published 2023-08-01“…Using the concept of Chinese expansion proposed by Kwee Kui Han, this research found that the Chinese were able to establish very structured and systematic presence in the island, both in its hinterland and coastal areas. …”
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From the Ethnic History of Asia – the Dōnghú, Wūhuán and Xiānbēi Proto-Mongolian Tribes
Published 2012-04-01“…At the end of the 1st century B.C. the Chinese Hàn Empire firstly established relations with the Wūhuán tribes and in the middle of the 1st century A.D. with the Xiānbēi tribes, too. …”
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Case Report: A Chinese Family of Type A Insulin Resistance Syndrome With Diabetes Mellitus, With a Novel Heterozygous Missense Mutation of the Insulin Receptor Gene
Published 2022-05-01“…One patient from the Chinese Han family exhibited signs and symptoms of TAIRS and was presented for evaluation. …”
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新加坡道教斋醮功能性研究 = A study on functionality of Singapore taoist ritual : observations from Jin Fu Gong Temple and Nanyang Neo Clan “Qing Jiao” rituals
Published 2011“…“Zhai Jiao” has been incorporated in Taoist ceremonies ever since the Han Dynasty, creating a history of more than a millennium. …”
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Final Year Project (FYP) -
1749
Comprehensive evaluations of individual discrimination, kinship analysis, genetic relationship exploration and biogeographic origin prediction in Chinese Dongxiang group by a 60-pl...
Published 2023-03-01“…Additionally, Dongxiang group had the close genetic distances with populations in East Asia, especially showed the intimate genetic relationships with Chinese Han populations, which were concluded from the genetic affinities and genetic background analyses of Dongxiang group and 33 reference populations. …”
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The Association of Type 2 Diabetes Loci Identified in Genome-Wide Association Studies with Metabolic Syndrome and Its Components in a Chinese Population with Type 2 Diabetes.
Published 2015-01-01“…In conclusion, these findings highlight the contribution of T2D-related genetic loci to MetS in a Chinese Han population. The study also provides insight into the pleotropic effects of genome-wide association loci of diabetes on metabolic regulation.…”
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Polymorphisms of the <i>BMPR1B</i>, <i>BMP15</i> and <i>GDF9</i> fecundity genes in four Chinese sheep breeds
Published 2024-02-01“…These results preliminarily showed that the <i>BMPR1B</i> and <i>GDF9</i> might be major genes influencing the prolificacy of Chinese sheep breeds.</p>…”
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Multiple founding paternal lineages inferred from the newly-developed 639-plex Y-SNP panel suggested the complex admixture and migration history of Chinese people
Published 2023-03-01“…Clustering patterns in principal component analysis and multidimensional scaling results showed a genetic differentiation between Tai-Kadai-speaking Li, Mongolic-speaking Mongolian, and other Sinitic-speaking Han Chinese populations. Phylogenetic topology inferred from the BEAST and Network relationships reconstructed from the popART further showed the founding lineages from culturally/linguistically diverse populations, such as C2a/C2b was dominant in Mongolian people and O1a/O1b was dominant in island Li people. …”
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Genetic variants of IDE-KIF11-HHEX at 10q23.33 associated with type 2 diabetes risk: a fine-mapping study in Chinese population.
Published 2012-01-01“…A cumulative effect of rs7923837 and rs1111875 was observed with individuals carrying 1, 2, and 3 or 4 risk alleles having a 1.27, 1.44, and 1.73-fold increased risk, respectively, for type 2 diabetes (P for trend = 4.1E-10).Our results confirm that genetic variants of the IDE-KIF11-HHEX region at 10q23.33 contribute to type 2 diabetes susceptibility and suggest that rs7923837 may represent the strongest signal related to type 2 diabetes risk in the Chinese Han population.…”
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A novel heterozygous variant of the COL4A4 gene in a Chinese family with hematuria and proteinuria leads to focal segmental glomerulosclerosis and chronic kidney disease
Published 2020-12-01“…The aim of this study was to identify the genetic lesion of a Chinese family with FSGS and CKD. Methods In this study, we recruited a Han‐Chinese family with unexplained high serum creatinine, hematuria, and proteinuria. …”
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Eating Spicy Food, Dietary Approaches to Stop Hypertension (DASH) Score, and Their Interaction on Incident Stroke in Southwestern Chinese Aged 30–79: A Prospective Cohort Study
Published 2023-02-01“…This study aimed to explore the association of eating spicy food, DASH score, and their interaction with stroke incidence. We included 22,160 Han residents aged 30–79 in southwest China from the China Multi-Ethnic Cohort. …”
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HTRA1 rs11528744, BCRA1 rs9928736, and B3GLCT rs4381465 are associated with age-related macular degeneration in a Chinese population
Published 2022-09-01“…The aim of this study was to investigate the association of these SNPs in a Han Chinese population.Methods: There were 576 patients with wet AMD and 572 healthy controls collected in this study. …”
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