Assessing the Potential Risks of Digital Therapeutics (DTX): The DTX Risk Assessment Canvas by Kerstin Denecke, Richard May, Elia Gabarron, Guillermo H. Lopez-Campos

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Molecular analysis of blood-associated pathogens in European wildcats (Felis silvestris silvestris) from Germany by Maria Sophia Unterköfler, Josef Harl, Bita Shahi Barogh, Joachim Spergser, Kristýna Hrazdilová, Franz Müller, Diana Jeschke, Ole Anders, Peter Steinbach, Hermann Ansorge, Hans-Peter Fuehrer, Mike Heddergott

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The Interleukin 6 Protein Level as well as a Genetic Variants, (rs1800795, rs1800797) Are Associated with Adverse Cardiovascular Outcomes within 10-Years Follow-Up by Susanne Schulz, Selina Rehm, Axel Schlitt, Kerstin Bitter, Stefan Reichert

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Digital health as an enabler for hospital@home: A rising trend or just a vision? by Kerstin Denecke, Richard May, Elizabeth M. Borycki, Andre W. Kushniruk

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Forces and moments generated by 3D direct printed clear aligners of varying labial and lingual thicknesses during lingual movement of maxillary central incisor: an in vitro study by James Grant, Patrick Foley, Brent Bankhead, Gabriel Miranda, Samar M. Adel, Ki Beom Kim

“…DPAs were directly 3D-printed with Tera Harz TC-85 (Graphy Inc., Seoul, South Korea) clear photocurable resin in 100-µm layers. …”
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Seed Oil Biochemical Composition of Cultivated <i>Cucurbita</i> L. Species from the VIR Collections Grown in the Astrakhan Province of the Russian Federation by Tatyana V. Shelenga, Tatyana M. Piskunova, Leonid L. Malyshev, Aimat A. Taipakova, Alla E. Solovyeva

“…The accessions of <i>Cucurbita mixta</i> Pang. were noted for high values of saturated FAs (palmitic and stearic), those of <i>Cucurbita pepo</i> var. <i>melopepo</i> (L.) Harz. of linoleic and linolenic, and those of <i>Cucurbita pepo</i> L. of oleic acid. …”
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C-Reactive Protein Level and the Genetic Variant rs1130864 in the CRP Gene as Prognostic Factors for 10-Year Cardiovascular Outcome by Susanne Schulz, Selina Rehm, Axel Schlitt, Madlen Lierath, Henriette Lüdike, Britt Hofmann, Kerstin Bitter, Stefan Reichert

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Hydrodynamic model for independent cold and thermo-mineral twin springs in a stratified continental karst aquifer, Camou, Arbailles Massif, Pyrénées, France by Philippe Audra, Jean-Yves Bigot, Dimitri Laurent, Nathalie Vanara, Didier Cailhol, Gérard Cazenave

“…Such type of stratified aquifer linked to density differences is common in coastal karst (Florida, French Calanques…), in the continental evaporite karst (Schlotten of the Harz in Germany, Kungur karst in Ural…), but remains poorly identified in continental carbonate karst areas, mainly because of the difficulty of access. …”
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Wildfire smoke triggers cirrus formation: lidar observations over the eastern Mediterranean by R.-E. Mamouri, R.-E. Mamouri, A. Ansmann, K. Ohneiser, D. A. Knopf, A. Nisantzi, A. Nisantzi, J. Bühl, J. Bühl, R. Engelmann, A. Skupin, P. Seifert, H. Baars, D. Ene, U. Wandinger, D. Hadjimitsis, D. Hadjimitsis

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Electrical conduction of ion tracks in tetrahedral amorphous carbon: temperature, field and doping dependence and comparison with matrix data by J Krauser, H-G Gehrke, H Hofsäss, J Amani, C Trautmann, A Weidinger

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Mechanical and surface properties of a 3D-printed dental resin reinforced with graphene by Helena Salgado, Joana Fialho, Marco Marques, Mário Vaz, Maria Helena Figueiral, Pedro Mesquita

“…Methods: A 3D-printed dental resin (Dental Sand, Harz Lab) was loaded with four different graphene nanoplatelet (Graphenest) concentrations: 0.01wt%, 0.1wt%, 0.25wt%, and 0.5wt%. …”
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Second Edition of the German–Austrian S3 Guideline “Infarction-Related Cardiogenic Shock: Diagnosis, Monitoring and Treatment” by Kevin Pilarczyk, Udo Boeken, Martin Russ, Josef Briegel, Michael Buerke, Alexander Geppert, Uwe Janssens, Malte Kelm, Guido Michels, Axel Schlitt, Holger Thiele, Stephan Willems, Uwe Zeymer, Bernhard Zwissler, Georg Delle-Karth, Markus Wolfgang Ferrari, Hans Reiner Figulla, Axel Heller, Gerhard Hindricks, Emel Pichler-Cetin, Burkert Pieske, Roland Prondzinsky, Johann Bauersachs, Ina Kopp, Karl Werdan, Matthias Thielmann

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Real-World Evaluation of Quality of Life, Effectiveness, and Safety of Aflibercept Plus FOLFIRI in Patients with Metastatic Colorectal Cancer: The Prospective QoLiTrap Study by Ralf-Dieter Hofheinz, Sandro Anchisi, Birgit Grünberger, Hans G. Derigs, Mark-Oliver Zahn, Christine Geffriaud-Ricouard, Max Gueldner, Christine Windemuth-Kieselbach, Stefanie Pederiva, Pierre Bohanes, Felicitas Scholten, Gudrun Piringer, Josef Thaler, Roger von Moos

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Systematic Review of PCR Proof of Parvovirus B19 Genomes in Endomyocardial Biopsies of Patients Presenting with Myocarditis or Dilated Cardiomyopathy by Angelos G. Rigopoulos, Bianca Klutt, Marios Matiakis, Athanasios Apostolou, Sophie Mavrogeni, Michel Noutsias

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Safety and efficacy of renal sympathetic denervation: a 9-year long-term follow-up of 24-hour ambulatory blood pressure measurements by Alexander Vogt, Jochen Dutzmann, Michael Nußbaum, Daniel Hoyer, Jörn Tongers, Axel Schlitt, Daniel Sedding, Alexander Plehn, Alexander Plehn

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The Open Anchoring Quest Dataset: Anchored Estimates from 96 Studies on Anchoring Effects by Lukas Röseler, Lucia Weber, Katharina Helgerth, Elena Stich, Miriam Günther, Paulina Tegethoff, Felix Wagner, M. Antunovic, F. Barrera-Lemarchand, E. Halali, K. Ioannidis, O. Genschow, N. Milstein, D. C. Molden, F. Papenmeier, Z. Pavlovic, R. Rinn, M. L. Schreiter, M. F. Zimdahl, Š. Bahník, C. Bermeitinger, F. B. N. Blower, H. L. Bögler, P. Burgmer, N. N. Cheek, L. Dorsch, S. Fels, M.-L. Frech, L. Freira, A. J. L. Harris, J. A. Häusser, M. V. Hedgebeth, M. Henkel, D. Horvath, P. Intelmann, A. Klamar, E. Knappe, L.-M. Köppel, S. M. Krueger, S. Lagator, F. Lopez-Boo, J. Navajas, J. K. Norem, J. Novak, Y. Onuki, E. Page, T. R. Rebholz, M. Sartorio, S. Schindler, D. R. Shanks, M.-C. Siems, P. Stäglich, M. Starkulla, M. Stitz, T. Straube, K. Thies, E. Thum, K. Ueda, M. Undorf, D. Urlichich, M. A. Vadillo, H. Wolf, A. Zhou, A. Schütz

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Anti-hormonal maintenance treatment with the CDK4/6 inhibitor ribociclib after 1st line chemotherapy in hormone receptor positive / HER2 negative metastatic breast cancer: A phase... by Thomas Decker, Kerstin Lüdtke-Heckenkamp, Luidmila Melnichuk, Nader Hirmas, Kristina Lübbe, Mark-Oliver Zahn, Marcus Schmidt, Carsten Denkert, Ralf Lorenz, Volkmar Müller, Dirk-Michael Zahm, Christoph Mundhenke, Stefan Bauer, Marc Thill, Peter Seropian, Natalie Filmann, Sibylle Loibl

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Foliar Application of Different Iron Sources Improves Morpho-Physiological Traits and Nutritional Quality of Broad Bean Grown in Sandy Soil by Abdel Wahab M. Mahmoud, Amira A. Ayad, Hend S. M. Abdel-Aziz, Leonard L. Williams, Rasha M. El-Shazoly, Ahmed Abdel-Wahab, Emad A. Abdeldaym

“…This research was implemented on broad bean plants (<i>Vicia faba</i> L. var. major Harz) to examine the impact of three iron sources: nano-iron (FeNPs, T1), iron sulfate (T2), and chelated iron (T3) as a foliar spray on the morphological properties, physiological attributes, and nutritional status of these plants compared to the untreated plants (control). …”
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Metatranscriptomics Reveals the RNA Virome of Ixodes Persulcatus in the China–North Korea Border, 2017 by Ruichen Wang, Shenghui Liu, Hongliang Sun, Chongxiao Xu, Yanhan Wen, Xiwen Wu, Weijia Zhang, Kai Nie, Fan Li, Shihong Fu, Qikai Yin, Ying He, Songtao Xu, Guodong Liang, Liquan Deng, Qiang Wei, Huanyu Wang

“…Notably, a new segmented flavivirus, named Baishan Forest Tick Virus, were identified, closely related to Alongshan virus and Harz mountain virus. Therefore, this new virus may pose a potential threat to humans. …”
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Editorial by sui-generis Redaktion

“…Mit sui-generis.ch schreiten wir zur Tat, wir schmelzen das Harz. Sie – liebe Leserinnen und Leser – schauen in diesem Augenblick auf die erste juristische Open-Access-Zeitschrift der Schweiz. …”
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