LipidSeq: a next-generation clinical resequencing panel for monogenic dyslipidemias[S] by Christopher T. Johansen, Joseph B. Dubé, Melissa N. Loyzer, Austin MacDonald, David E. Carter, Adam D. McIntyre, Henian Cao, Jian Wang, John F. Robinson, Robert A. Hegele

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Carnitine palmitoyltransferase IA polymorphism P479L is common in Greenland Inuit and is associated with elevated plasma apolipoprotein A-I by Chandheeb Rajakumar, Matthew R. Ban, Henian Cao, T. Kue Young, Peter Bjerregaard, Robert A. Hegele

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Characterization of high density lipoprotein particles in familial apolipoprotein A-I deficiency1 by Raul D. Santos, Ernst J. Schaefer, Bela F. Asztalos, Eliana Polisecki, Jian Wang, Robert A. Hegele, Lilton R.C. Martinez, Marcio H. Miname, Carlos E. Rochitte, Protasio L. Da Luz, Raul C. Maranhão

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Consideration and Application of Lipoprotein(a) in the Risk Assessment of Atherosclerotic Cardiovascular Disease Risk in Adults by Tiffany Yuen, MD, FRCPC, G.B. John Mancini, MD, FRCPC, FACP, FACC, Robert A. Hegele, MD, FRCPC, Glen J. Pearson, PharmD, FCCS

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Targeted next generation sequencing as a tool for precision medicine by Markus Gulilat, Tyler Lamb, Wendy A. Teft, Jian Wang, Jacqueline S. Dron, John F. Robinson, Rommel G. Tirona, Robert A. Hegele, Richard B. Kim, Ute I. Schwarz

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Gene-centric meta-analysis of lipid traits in African, East Asian and Hispanic populations. by Clara C Elbers, Yiran Guo, Vinicius Tragante, Erik P A van Iperen, Matthew B Lanktree, Berta Almoguera Castillo, Fang Chen, Lisa R Yanek, Mary K Wojczynski, Yun R Li, Bart Ferwerda, Christie M Ballantyne, Sarah G Buxbaum, Yii-Der Ida Chen, Wei-Min Chen, L Adrienne Cupples, Mary Cushman, Yanan Duan, David Duggan, Michele K Evans, Jyotika K Fernandes, Myriam Fornage, Melissa Garcia, W Timothy Garvey, Nicole Glazer, Felicia Gomez, Tamara B Harris, Indrani Halder, Virginia J Howard, Margaux F Keller, M Ilyas Kamboh, Charles Kooperberg, Stephen B Kritchevsky, Andrea LaCroix, Kiang Liu, Yongmei Liu, Kiran Musunuru, Anne B Newman, N Charlotte Onland-Moret, Jose Ordovas, Inga Peter, Wendy Post, Susan Redline, Steven E Reis, Richa Saxena, Pamela J Schreiner, Kelly A Volcik, Xingbin Wang, Salim Yusuf, Alan B Zonderland, Sonia S Anand, Diane M Becker, Bruce Psaty, Daniel J Rader, Alex P Reiner, Stephen S Rich, Jerome I Rotter, Michèle M Sale, Michael Y Tsai, Ingrid B Borecki, Robert A Hegele, Sekar Kathiresan, Michael A Nalls, Herman A Taylor, Hakon Hakonarson, Suthesh Sivapalaratnam, Folkert W Asselbergs, Fotios Drenos, James G Wilson, Brendan J Keating

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Sortilin enhances secretion of apolipoprotein(a) through effects on apolipoprotein B secretion and promotes uptake of lipoprotein(a) by Justin R. Clark, Matthew Gemin, Amer Youssef, Santica M. Marcovina, Annik Prat, Nabil G. Seidah, Robert A. Hegele, Michael B. Boffa, Marlys L. Koschinsky

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Variants at the APOE/C1/C2/C4 Locus Modulate Cholesterol Efflux Capacity Independently of High‐Density Lipoprotein Cholesterol by Cécile Low‐Kam, David Rhainds, Ken Sin Lo, Amina Barhdadi, Marie Boulé, Sonia Alem, Valérie Pedneault‐Gagnon, Eric Rhéaume, Marie‐Pierre Dubé, David Busseuil, Robert A. Hegele, Guillaume Lettre, Jean‐Claude Tardif

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Ambroxol as a novel disease-modifying treatment for Parkinson’s disease dementia: protocol for a single-centre, randomized, double-blind, placebo-controlled trial by C. R. A. Silveira, J. MacKinley, K. Coleman, Z. Li, E. Finger, R. Bartha, S. A. Morrow, J. Wells, M. Borrie, R. G. Tirona, C. A. Rupar, G. Zou, R. A. Hegele, D. Mahuran, P. MacDonald, M. E. Jenkins, M. Jog, S. H. Pasternak

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Polygenic determinants in extremes of high-density lipoprotein cholesterol by Jacqueline S. Dron, Jian Wang, Cécile Low-Kam, Sumeet A. Khetarpal, John F. Robinson, Adam D. McIntyre, Matthew R. Ban, Henian Cao, David Rhainds, Marie-Pierre Dubé, Daniel J. Rader, Guillaume Lettre, Jean-Claude Tardif, Robert A. Hegele

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Large-scale deletions of the ABCA1 gene in patients with hypoalphalipoproteinemia by Jacqueline S. Dron, Jian Wang, Amanda J. Berberich, Michael A. Iacocca, Henian Cao, Ping Yang, Joan Knoll, Karine Tremblay, Diane Brisson, Christian Netzer, Ioanna Gouni-Berthold, Daniel Gaudet, Robert A. Hegele

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Meta-analysis of the INSIG2 association with obesity including 74,345 individuals: does heterogeneity of estimates relate to study design? by Iris M Heid, Cornelia Huth, Ruth J F Loos, Florian Kronenberg, Vera Adamkova, Sonia S Anand, Kristin Ardlie, Heike Biebermann, Peter Bjerregaard, Heiner Boeing, Claude Bouchard, Marina Ciullo, Jackie A Cooper, Dolores Corella, Christian Dina, James C Engert, Eva Fisher, Francesc Francès, Philippe Froguel, Johannes Hebebrand, Robert A Hegele, Anke Hinney, Margret R Hoehe, Frank B Hu, Jaroslav A Hubacek, Steve E Humphries, Steven C Hunt, Thomas Illig, Marjo-Riita Järvelin, Marika Kaakinen, Barbara Kollerits, Heiko Krude, Jitender Kumar, Leslie A Lange, Birgit Langer, Shengxu Li, Andreas Luchner, Helen N Lyon, David Meyre, Karen L Mohlke, Vincent Mooser, Almut Nebel, Thuy Trang Nguyen, Bernhard Paulweber, Louis Perusse, Lu Qi, Tuomo Rankinen, Dieter Rosskopf, Stefan Schreiber, Shantanu Sengupta, Rossella Sorice, Anita Suk, Gudmar Thorleifsson, Unnur Thorsteinsdottir, Henry Völzke, Karani S Vimaleswaran, Nicholas J Wareham, Dawn Waterworth, Salim Yusuf, Cecilia Lindgren, Mark I McCarthy, Christoph Lange, Joel N Hirschhorn, Nan Laird, H-Erich Wichmann

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Increased Density of Growth Differentiation Factor-15+ Immunoreactive M1/M2 Macrophages in Prostate Cancer of Different Gleason Scores Compared with Benign Prostate Hyperplasia by Gabriel A. Bonaterra, Alexander Schleper, Maximilian Skowronek, Lucia S. Kilian, Theresa Rink, Hans Schwarzbach, Hendrik Heers, Jörg Hänze, Peter Rexin, Annette Ramaswamy, Carsten Denkert, Beate Wilhelm, Axel Hegele, Rainer Hofmann, Eberhard Weihe, Ralf Kinscherf

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Inflammation Profiling of Critically Ill Coronavirus Disease 2019 Patients by Douglas D. Fraser, MD, PhD, Gediminas Cepinskas, DVM, PhD, Marat Slessarev, MD, MSc, Claudio Martin, MD, MSc, Mark Daley, PhD, Michael R. Miller, PhD, David B. O’Gorman, PhD, Sean E. Gill, PhD, Eric K. Patterson, PhD, Claudia C. dos Santos, MD, MSc, on behalf of the Lawson COVID-19 Study Team, Robert Arntfield, Ian Ball, Gordon Barkwell, Tracey Bentall, Karen Bosma, Saoirse Cameron, Eileen Campbell, David Carter, Carolina Gillio-Meina, Robert Hegele, Natalya Odoardi, Ram Singh, Kelly Summers, Sue Tereschyn

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In-Situ XRD Study of Phase Transformation Kinetics in a Co-Cr-W-Alloy Manufactured by Laser Powder-Bed Fusion by Patrick Hegele, Jonas von Kobylinski, Leonhard Hitzler, Christian Krempaszky, Ewald Werner

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Determination of lipoprotein(a) kringle repeat number from genomic DNA: copy number variation genotyping using qPCR* by Matthew B. Lanktree, Chandheeb Rajakumar, J. Howard Brunt, Marlys L. Koschinsky, Philip W. Connelly, Robert A. Hegele

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Saudi Familial Hypercholesterolemia Patients With Rare LDLR Stop Gain Variant Showed Variable Clinical Phenotype and Resistance to Multiple Drug Regimen by Zuhier Ahmed Awan, Zuhier Ahmed Awan, Omran M. Rashidi, Omran M. Rashidi, Omran M. Rashidi, Bandar Ali Al-Shehri, Bandar Ali Al-Shehri, Kaiser Jamil, Ramu Elango, Ramu Elango, Jumana Y. Al-Aama, Jumana Y. Al-Aama, Robert A. Hegele, Babajan Banaganapalli, Babajan Banaganapalli, Noor A. Shaik, Noor A. Shaik

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Metabolomics Profiling of Critically Ill Coronavirus Disease 2019 Patients: Identification of Diagnostic and Prognostic Biomarkers by Douglas D. Fraser, MD, PhD, Marat Slessarev, MD, MSc, Claudio M. Martin, MD, MSc, Mark Daley, PhD, Maitray A. Patel, BSc, Michael R. Miller, PhD, Eric K. Patterson, PhD, David B. O’Gorman, PhD, Sean E. Gill, PhD, David S. Wishart, PhD, Rupasri Mandal, PhD, Gediminas Cepinskas, DVM, PhD, On behalf of the Lawson COVID19 Study Team, Robert Arntfield, Ian Ball, Gordon Barkwell, Tracey Bentall, Karen Bosma, Saoirse Cameron, Eileen Campbell, David Carter, Carolina Gillio-Meina, Robert Hegele, Natalya Odoardi, Ram Singh, Kelly Summers, Sue Tereschyn

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Characterization of a novel mutation causing hepatic lipase deficiency among French Canadians by Isabelle L. Ruel, Patrick Couture, Claude Gagné, Yves Deshaies, Jacques Simard, Robert A. Hegele, Benoît Lamarche

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Endothelial Injury and Glycocalyx Degradation in Critically Ill Coronavirus Disease 2019 Patients: Implications for Microvascular Platelet Aggregation by Douglas D. Fraser, MD, PhD, Eric K. Patterson, PhD, Marat Slessarev, MD, MSc, Sean E. Gill, PhD, Claudio Martin, MD, MSc, Mark Daley, PhD, Michael R. Miller, PhD, Maitray A. Patel, BSc, Claudia C. dos Santos, MD, MSc, Karen J. Bosma, MD, David B. O’Gorman, PhD, Gediminas Cepinskas, DVM, PhD, on behalf of the Lawson COVID19 Study Team, Robert Arntfield, Ian Ball, Gordon Barkwell, Tracey Bentall, Karen Bosma, Saoirse Cameron, Eileen Campbell, David Carter, Carolina Gillio-Meina, Robert Hegele, Natalya Odoardi, Ram Singh, Kelly Summers, Sue Tereschyn

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