The ARCA Registry: A Collaborative Global Platform for Advancing Trial Readiness in Autosomal Recessive Cerebellar Ataxias by Andreas Traschütz, Andreas Traschütz, Selina Reich, Selina Reich, Astrid D. Adarmes, Astrid D. Adarmes, Mathieu Anheim, Mathieu Anheim, Mathieu Anheim, Mahmoud Reza Ashrafi, Jonathan Baets, Jonathan Baets, Jonathan Baets, A. Nazli Basak, Enrico Bertini, Bernard Brais, Cynthia Gagnon, Janina Gburek-Augustat, Hasmet A. Hanagasi, Anna Heinzmann, Rita Horvath, Peter de Jonghe, Peter de Jonghe, Peter de Jonghe, Christoph Kamm, Peter Klivenyi, Thomas Klopstock, Thomas Klopstock, Thomas Klopstock, Martina Minnerop, Martina Minnerop, Martina Minnerop, Alexander Münchau, Mathilde Renaud, Mathilde Renaud, Richard H. Roxburgh, Richard H. Roxburgh, Filippo M. Santorelli, Tommaso Schirinzi, Tommaso Schirinzi, Deborah A. Sival, Dagmar Timmann, Stefan Vielhaber, Stefan Vielhaber, Stefan Vielhaber, Michael Wallner, Bart P. van de Warrenburg, Ginevra Zanni, Stephan Zuchner, Thomas Klockgether, Thomas Klockgether, Rebecca Schüle, Rebecca Schüle, Ludger Schöls, Ludger Schöls, PREPARE Consortium, Matthis Synofzik, Matthis Synofzik

Get full text

Hepatocyte-specific activity of TSC22D4 triggers progressive NAFLD by impairing mitochondrial function by Gretchen Wolff, Minako Sakurai, Amit Mhamane, Maria Troullinaki, Adriano Maida, Ioannis K. Deligiannis, Kelvin Yin, Peter Weber, Jakob Morgenstern, Annika Wieder, Yun Kwon, Revathi Sekar, Anja Zeigerer, Michael Roden, Matthias Blüher, Nadine Volk, Tanja Poth, Thilo Hackert, Lena Wiedmann, Francesca De Angelis Rigotti, Juan Rodriguez-Vita, Andreas Fischer, Rajesh Mukthavaram, Pattraranee Limphong, Kiyoshi Tachikawa, Priya Karmali, Joseph Payne, Padmanabh Chivukula, Bilgen Ekim-Üstünel, Celia P. Martinez-Jimenez, Julia Szendrödi, Peter Nawroth, Stephan Herzig

Get full text

Deciphering imprints of impaired memory B-cell maturation in germinal centers of three patients with common variable immunodeficiency by Pauline van Schouwenburg, Pauline van Schouwenburg, Susanne Unger, Susanne Unger, Susanne Unger, Kathryn J. Payne, Kathryn J. Payne, Kathryn J. Payne, Fabian M. P. Kaiser, Fabian M. P. Kaiser, Ingrid Pico-Knijnenburg, Jens Pfeiffer, Oliver Hausmann, David Friedmann, David Friedmann, David Friedmann, Michelle Erbel, Maximilian Seidl, Maximilian Seidl, David van Zessen, Andrew P. Stubbs, Mirjam van der Burg, Klaus Warnatz, Klaus Warnatz

Get full text

Localization Techniques for Non-Palpable Breast Lesions: Current Status, Knowledge Gaps, and Rationale for the MELODY Study (EUBREAST-4/iBRA-NET, NCT 05559411) by Maggie Banys-Paluchowski, Thorsten Kühn, Yazan Masannat, Isabel Rubio, Jana de Boniface, Nina Ditsch, Güldeniz Karadeniz Cakmak, Andreas Karakatsanis, Rajiv Dave, Markus Hahn, Shelley Potter, Ashutosh Kothari, Oreste Davide Gentilini, Bahadir M. Gulluoglu, Michael Patrick Lux, Marjolein Smidt, Walter Paul Weber, Bilge Aktas Sezen, Natalia Krawczyk, Steffi Hartmann, Rosa Di Micco, Sarah Nietz, Francois Malherbe, Neslihan Cabioglu, Nuh Zafer Canturk, Maria Luisa Gasparri, Dawid Murawa, James Harvey

Get full text

Differential Role for Activating FcγRIII in Neointima Formation After Arterial Injury and Diet-Induced Chronic Atherosclerosis in Apolipoprotein E-Deficient Mice by Yaw Asare, Yaw Asare, Janine Koehncke, Jaco Selle, Jaco Selle, Sakine Simsekyilmaz, Joachim Jankowski, Joachim Jankowski, Gansuvd Shagdarsuren, Johannes E. Gessner, Jürgen Bernhagen, Jürgen Bernhagen, Erdenechimeg Shagdarsuren, Erdenechimeg Shagdarsuren

Get full text

Factors Influencing the Adjuvant Therapy Decision: Results of a Real-World Multicenter Data Analysis of 904 Melanoma Patients by Georg Lodde, Andrea Forschner, Jessica Hassel, Lena M. Wulfken, Friedegund Meier, Peter Mohr, Katharina Kähler, Bastian Schilling, Carmen Loquai, Carola Berking, Svea Hüning, Kerstin Schatton, Christoffer Gebhardt, Julia Eckardt, Ralf Gutzmer, Lydia Reinhardt, Valerie Glutsch, Ulrike Nikfarjam, Michael Erdmann, Andreas Stang, Bernd Kowall, Alexander Roesch, Selma Ugurel, Lisa Zimmer, Dirk Schadendorf, Elisabeth Livingstone

Get full text

Comprehensive characterization of the postoperative pericardial inflammatory response: Potential implications for clinical outcomesCentral MessagePerspective by Ali Fatehi Hassanabad, MD, MSc, Friederike I. Schoettler, MD, William D.T. Kent, MD, MSc, Corey A. Adams, MD, MSc, Daniel D. Holloway, MD, MSc, Imtiaz S. Ali, MD, Richard J. Novick, MD, MSc, Muhammad R. Ahsan, MBBS, Robert Scott McClure, MD, MSc, Ganesh Shanmugam, MD, William T. Kidd, MD, Teresa M. Kieser, MD, PhD, Paul W.M. Fedak, MD, PhD, Justin F. Deniset, PhD

Get full text

Experiences with IL-1 blockade in systemic juvenile idiopathic arthritis – data from the German AID-registry by Elke Lainka, Melanie Baehr, Bernadette Raszka, Johannes-Peter Haas, Boris Hügle, Nadine Fischer, Dirk Foell, Claas Hinze, Elisabeth Weissbarth-Riedel, Tilmann Kallinich, Gerd Horneff, Daniel Windschall, Eggert Lilienthal, Tim Niehues, Ulrich Neudorf, Rainer Berendes, Rolf-Michael Küster, Prasad Thomas Oommen, Christoph Rietschel, Thomas Lutz, Frank Weller-Heinemann, Klaus Tenbrock, Georg Leonhard Heubner, Jens Klotsche, Helmut Wittkowski

Get full text

Multiparametric ¹⁸F-FDG PET/MRI-Based Radiomics for Prediction of Pathological Complete Response to Neoadjuvant Chemotherapy in Breast Cancer by Lale Umutlu, Julian Kirchner, Nils-Martin Bruckmann, Janna Morawitz, Gerald Antoch, Saskia Ting, Ann-Kathrin Bittner, Oliver Hoffmann, Lena Häberle, Eugen Ruckhäberle, Onofrio Antonio Catalano, Michal Chodyla, Johannes Grueneisen, Harald H. Quick, Wolfgang P. Fendler, Christoph Rischpler, Ken Herrmann, Peter Gibbs, Katja Pinker

Get full text

The association of premorbid conditions with 6-month mortality in acutely admitted ICU patients over 80 years by Dylan W. de Lange, Ivo W. Soliman, Susannah Leaver, Ariane Boumendil, Lenneke E. M. Haas, Ximena Watson, Carol Boulanger, Wojciech Szczeklik, Antonio Artigas, Alessandro Morandi, Finn Andersen, Christian Jung, Rui Moreno, Sten Walther, Sandra Oeyen, Joerg C. Schefold, Maurizio Cecconi, Brian Marsh, Michael Joannidis, Yuriy Nalapko, Muhammed Elhadi, Jesper Fjølner, Bertrand Guidet, Hans Flaatten, the VIP2 study group

Get full text

Characterisation and clinical outcomes in children and adolescents with diabetes according to newly defined subgroups: a cohort study from the DPV registryResearch in context by Katharina Warncke, Alexander Eckert, Ezio Bonifacio, Peter Achenbach, Olga Kordonouri, Thomas Meissner, Ute Ohlenschläger, Walter Bonfig, Anette-G. Ziegler, Reinhard W. Holl

Get full text

Experimental Validation of an Analytical Program and a Monte Carlo Simulation for the Computation of the Far Out-of-Field Dose in External Beam Photon Therapy Applied to Pediatric... by Marijke De Saint-Hubert, Finja Suesselbeck, Finja Suesselbeck, Fabiano Vasi, Florian Stuckmann, Florian Stuckmann, Miguel Rodriguez, Miguel Rodriguez, Jérémie Dabin, Beate Timmermann, Beate Timmermann, Beate Timmermann, Beate Timmermann, Beate Timmermann, Isabelle Thierry-Chef, Isabelle Thierry-Chef, Isabelle Thierry-Chef, Uwe Schneider, Lorenzo Brualla, Lorenzo Brualla, Lorenzo Brualla

Get full text

Postoperative adjuvant radiochemotherapy with cisplatin versus adjuvant radiochemotherapy with cisplatin and pembrolizumab in locally advanced head and neck squamous cell carcinoma... by Susanne Wiegand, Gunnar Wichmann, Jeannette Vogt, Kathrin Vogel, Annegret Franke, Thomas Kuhnt, Florian Lordick, Anne-Marie Scheuble, Peter Hambsch, Peter Brossart, Franz Georg Bauernfeind, Holger Kaftan, Georg Maschmeyer, Matthias Paland, Marc Münter, Victor Lewitzki, Nicole Rotter, Carmen Stromberger, Carmen Stromberger, Marcus Beck, Steffen Dommerich, Thomas Christoph Gauler, Gunnar Hapke, Orlando Guntinas-Lichius, Ursula Schröder, Martin Görner, Matthias G. Hautmann, Felix Steger, Bálint Tamaskovics, Anett Schmiedeknecht, Andreas Dietz

Get full text

Prognostic and Predictive Value of CCND1/Cyclin D1 Amplification in Breast Cancer With a Focus on Postmenopausal Patients: A Systematic Review and Meta-Analysis by Sarah A. Jeffreys, Sarah A. Jeffreys, Therese M. Becker, Therese M. Becker, Sarah Khan, Patsy Soon, Patsy Soon, Patsy Soon, Hans Neubauer, Paul de Souza, Paul de Souza, Paul de Souza, Branka Powter

Get full text

Lipid Signaling via Pkh1/2 Regulates Fungal CO₂ Sensing through the Kinase Sch9 by Susann Pohlers, Ronny Martin, Thomas Krüger, Daniela Hellwig, Frank Hänel, Olaf Kniemeyer, Hans Peter Saluz, Patrick Van Dijck, Joachim F. Ernst, Axel Brakhage, Fritz A. Mühlschlegel, Oliver Kurzai

Get full text

AMPLIFY-NEOVAC: a randomized, 3-arm multicenter phase I trial to assess safety, tolerability and immunogenicity of IDH1-vac combined with an immune checkpoint inhibitor targeting p... by Lukas Bunse, Anne-Kathleen Rupp, Isabel Poschke, Theresa Bunse, Katharina Lindner, Antje Wick, Jens Blobner, Martin Misch, Ghazaleh Tabatabai, Martin Glas, Oliver Schnell, Jens Gempt, Monika Denk, Guido Reifenberger, Martin Bendszus, Patrick Wuchter, Joachim P Steinbach, Wolfgang Wick, Michael Platten

Get full text

Functional and structural connectivity substrates of cognitive performance in relapsing remitting multiple sclerosis with mild disability by Arzu Ceylan Has Silemek, Lukas Fischer, Jana Pöttgen, Iris-Katharina Penner, Andreas K. Engel, Christoph Heesen, Stefan M. Gold, Jan-Patrick Stellmann

Get full text

Prior Stroke in PFO Patients Is Associated With Both PFO-Related and -Unrelated Factors by Timo Kahles, Patrik Michel, Alexander Hapfelmeier, Franz R. Eberli, Marialuisa Zedde, Vincent Thijs, Vincent Thijs, Markus Kraemer, Markus Kraemer, Stefan T. Engelter, Stefan T. Engelter, Joaquin Serena, Christian Weimar, Achim Mallmann, Andreas Luft, Dimitri Hemelsoet, David E. Thaler, Andreas Müller-Eichelberg, Adinda De Pauw, Roman Sztajzel, Carmel Armon, Carmel Armon, David M. Kent, Bernhard Meier, Heinrich P. Mattle, Urs Fischer, Marcel Arnold, Marie-Luise Mono, Krassen Nedeltchev, Krassen Nedeltchev, for the International PFO Consortium NCT00859885

Get full text

Predicting the earliest deviation in weight gain in the course towards manifest overweight in offspring exposed to obesity in pregnancy: a longitudinal cohort study by Delphina Gomes, Lien Le, Sarah Perschbacher, Nikolaus A. Haas, Heinrich Netz, Uwe Hasbargen, Maria Delius, Kristin Lange, Uta Nennstiel, Adelbert A. Roscher, Ulrich Mansmann, Regina Ensenauer

Get full text

N-Substituted 3-Aminooxindoles and N-Propargyl Derivatives: Potential Biological Activities against Alzheimer’s Disease by Tereza Hofmanova, Carolina Marques, Alfonso T. García-Sosa, Óscar López, Luisa Leitzbach, Elisabete P. Carreiro, Aday González-Bakker, Adrián Puerta, Holger Stark, José M. Padrón, José G. Fernández-Bolaños, Anthony J. Burke

Get full text