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    Estrogen metabolite ratio: Is the 2-hydroxyestrone to 16α-hydroxyestrone ratio predictive for breast cancer? by Nadia Obi, Alina Vrieling, Judith Heinz

    Published 2011-02-01
    “…Nadia Obi1, Alina Vrieling2, Judith Heinz1, Jenny Chang-Claude21University Cancer Center Hamburg (UCCH)/Hubertus Wald Tumor Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; 2Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, GermanyAbstract: Experimental studies have shown that two main estrogen metabolites hydroxylated by CYP1A1 and CYP1B1 in the breast differentially affect breast cell proliferation and carcinogenesis. …”
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