La intertextualidad en el cine de Álex de la Iglesia: el caso del cómic by Neftalí PÉREZ FRANCO

“…El cine de este cineasta está marcado por claras reminiscencias provenientes de las viñetas: los superhéroes patéticos de Acción mutante se mueven por un contexto futurista muy del cómic de ciencia ficción; el humor estereotipado y los personajes grotescos del tebeo de la editorial Bruguera inundan todas sus comedias; o también son destacables los diversos homenajes narrativos o estéticos a la escuela franco-belga de Hergé y Goscinny. Esta fuerte influencia recorre toda su filmografía desde la mencionada ópera prima Acción mutante, hasta Crimen Ferpecto, pasando por títulos como El día de la bestia, Perdita Durango, Muertos de risa o La comunidad, hasta convertirse en un autor  abanderado del fenómeno freak que marca tendencia en el cine español.…”
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Tintin et le futur antérieur : de la conjecture à l'anaphore by Meyer Jean-Paul

“…Dans les «Aventures de Tintin» (Hergé ; 23 albums publiés entre 1930 et 1976), l’emploi fréquent et marqué du futur antérieur conjectural (FAC) mérite une attention particulière. …”
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Identification and characterization of two novel KCNH2 mutations contributing to long QT syndrome. by Anthony Owusu-Mensah, Jacqueline Treat, Joyce Bernardi, Ryan Pfeiffer, Robert Goodrow, Bright Tsevi, Victoria Lam, Michel Audette, Jonathan M Cordeiro, Makarand Deo

“…Heterologous expression of P632L and S428P into HEK cells produced no hERG current compared to the wild type (WT). Moreover, the co-transfection of WT and P632L yielded no hERG current; however, the co-transfection of WT and S428P yielded partial hERG current. …”
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The link between accretion mode and environment in radio-loud active galaxies by Ineson, J, Croston, J, Hardcastle, M, Kraft, R, Evans, D, Jarvis, M

“…Comparing the samples, we found that although the maximum environment richness of the HERG environments is similar in both samples, there are poorer HERG environments in the z~0.1 sample than in the z~0.5 sample. …”

Anesthetic drug midazolam inhibits cardiac human ether-à-go-go-related gene channels: mode of action by Vonderlin N, Fischer F, Zitron E, Seyler C, Scherer D, Thomas D, Katus HA, Scholz EP

“…So far, the effects of midazolam on cardiac human ether-à-go-go-related gene (hERG) channels have not been analyzed. The inhibitory effects of midazolam on heterologously expressed hERG channels were analyzed in Xenopus oocytes using the double-electrode voltage clamp technique. …”
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Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk by Mirams, G, Cui, Y, Sher, A, Fink, M, Cooper, J, Heath, B, McMahon, N, Gavaghan, D, Noble, D

“…While avoiding the use of drugs with maximum therapeutic concentrations within 30-fold of their hERG inhibitory concentration 50% (IC50) values has been suggested, there are drugs that are exceptions to this rule: hERG inhibitors that do not cause TdP, and drugs that can cause TdP but are not strong hERG inhibitors. …”

Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk. by Mirams, G, Cui, Y, Sher, A, Fink, M, Cooper, J, Heath, B, McMahon, N, Gavaghan, D, Noble, D

“…While avoiding the use of drugs with maximum therapeutic concentrations within 30-fold of their hERG inhibitory concentration 50% (IC(50)) values has been suggested, there are drugs that are exceptions to this rule: hERG inhibitors that do not cause TdP, and drugs that can cause TdP but are not strong hERG inhibitors. …”

Structural properties of PAS domains from the KCNH potassium channels. by Ricardo Adaixo, Carol A Harley, Artur F Castro-Rodrigues, João H Morais-Cabral

“…We determined high resolution structures of PAS domains from the mouse EAG (mEAG), drosophila ELK (dELK) and human ERG (hERG) channels and also of the hERG domain without the first nine amino acids. …”
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A Novel <i>KCNH2</i> S981fs Mutation Identified by Whole-Exome Sequencing Is Associated with Type 2 Long QT Syndrome by Yu-Wen Cheng, Chia-Tung Wu, Chi-Jen Chang, Yung-Hsin Yeh, Gwo-Jyh Chang, Hsin-Yi Tsai, Lung-An Hsu

“…Co-immunoprecipitation experiments confirmed the assembly of mutant proteins with wild-type hERG. Confocal imaging showed decreased hERG distribution on the cell membrane in cells expressing S981fs. …”
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Novel Two-Step Classifier for Torsades de Pointes Risk Stratification from Direct Features by Jaimit Parikh, Viatcheslav Gurev, John J. Rice

“…While pre-clinical Torsades de Pointes (TdP) risk classifiers had initially been based on drug-induced block of hERG potassium channels, it is now well established that improved risk prediction can be achieved by considering block of non-hERG ion channels. …”
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The Stripe 82 1–2 GHz Very Large Array Snapshot Survey: host galaxy properties and accretion rates of radio galaxies by Whittam, I, Prescott, M, McAlpine, K, Jarvis, M, Heywood, I

“…Optical spectra are used to classify these sources as high excitation and low excitation radio galaxies (HERGs and LERGs), resulting in 60 HERGs, 149 LERGs, and 600 ‘probable LERGs’. …”

The radio galaxy population in the SIMBA simulations by Thomas, N, Jarvis, MJ, Davé, R, Anglés-Alcázar, D

“…SIMBA thus predicts that deeper radio surveys will reveal an increasing overlap between the host galaxy demographics of HERGs and LERGs.…”

Identification of small-molecule ion channel modulators in C. elegans channelopathy models by Qiang Jiang, Kai Li, Wen-Jing Lu, Shuang Li, Xin Chen, Xi-Juan Liu, Jie Yuan, Qiurong Ding, Feng Lan, Shi-Qing Cai

“…Mutations in the voltage-gated K+ channel human ether-a-go-go-related gene (hERG) lead to Long-QT syndrome, causing life-threatening cardiac arrhythmia. …”
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The Eag domain regulates the voltage-dependent inactivation of rat Eag1 K+ channels. by Ting-Feng Lin, Guey-Mei Jow, Hsin-Yu Fang, Ssu-Ju Fu, Hao-Han Wu, Mei-Miao Chiu, Chung-Jiuan Jeng

“…By contrast, the inactivation features were retained in the reverse hERG1 chimeras. Furthermore, an eag domain-lacking rEag1 deletion mutant also showed the fast phase of inactivation that was notably attenuated upon co-expression with the rEag1 eag domain fragment, but not with the hERG1 eag domain fragment. …”
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GAMA/WiggleZ: The 1.4GHz radio luminosity functions of high- and low-excitation radio galaxies and their redshift evolution to z=0.75 by Pracy, M, Ching, J, Sadler, E, Croom, S, Baldry, I, Bland-Hawthorn, J, Brough, S, Brown, M, Couch, W, Davis, T, Drinkwater, M, Jarvis, M, Jelliffe, B, Jurek, R, Loveday, J, Pimbblet, K, Prescott, M, Wisnioski, E, Woods, D

“…The radio AGN are separated into low-excitation radio galaxies (LERGs) and high-excitation radio galaxies (HERGs) using the optical spectra. We derive radio luminosity functions for LERGs and HERGs separately in the three redshift bins (0.005 &lt; z &lt; 0.3, 0.3 &lt; z &lt; 0.5 and 0.5 &lt; z &lt; 0.75). …”

MIGHTEE: the nature of the radio-loud AGN population by Whittam, IH, Jarvis, MJ, Hale, CL, Prescott, M, Morabito, LK, Heywood, I, Adams, NJ, Afonso, J, An, F, Ao, Y, Bowler, RAA, Collier, JD, Deane, RP, Delhaize, J, Frank, B, Glowacki, M, Hatfield, PW, Maddox, N, Marchetti, L, Matthews, AM, Prandoni, I, Randriamampandry, S, Randriamanakoto, Z, Smith, DJB, Taylor, AR, Thomas, NL, Vaccari, M

“…We find no significant difference in the host galaxy properties of the HERGs and LERGs in our sample. In contrast to previous work, we find that the HERGs and LERGs have very similar Eddington-scaled accretion rates; in particular we identify a population of very slowly accreting AGNs that are formally classified as HERGs at these low radio luminosities, where separating into HERGs and LERGs possibly becomes redundant. …”

Targeting potassium channels and autophagy to defeat chemoresistance by Giulia Petroni

“…Both autophagy and hERG1 potassium channels have been shown to promote tumor progression and resistance to treatment. …”
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A need for exhaustive and standardized characterization of ion channels activity. The case of KV11.1 by Malak Alameh, Malak Alameh, Barbara Ribeiro Oliveira-Mendes, Florence Kyndt, Jordan Rivron, Isabelle Denjoy, Florian Lesage, Jean-Jacques Schott, Michel De Waard, Michel De Waard, Gildas Loussouarn

“…hERG, the pore-forming subunit of the rapid component of the delayed rectifier K+ current, plays a key role in ventricular repolarization. …”
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The etomidate analog ET-26 HCl retains superior myocardial performance: Comparisons with etomidate in vivo and in vitro. by Xingxing Liu, Haibo Song, Jun Yang, Cheng Zhou, Yi Kang, Linghui Yang, Jin Liu, Wensheng Zhang

“…In addition, the electrophysiology study indicated that ET-26 HCl and etomidate inhibited the hERG at a supra-therapeutic concentration.…”
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Mutagenicity and safety pharmacology of a standardized antidiabetic polyherbal formulation by Fadzilah Adibah Abdul Majid, Anis Fadhlina, Hassan Fahmi Ismail, Siti Nurazwa Zainol, Archan Kumar Mamillapalli, Vijayabalaji Venkatesan, Rajesh Eswarappa, Renuka Pillai

“…Human ether-a-go-go-related gene (hERG) assay and Functional Observation Battery (FOB) were done for the safety pharmacology tests. …”
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