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    Statistical tools and community resources for developing trusted models in biology and chemistry by Daly, A

    Published 2017
    “…We demonstrate the Modeling Web Lab’s utility across multiple mod- eling domains by re-creating the results of a contemporary modeling study of the hERG ion channel model, as well as the results of an original study of electrochemical redox reactions.…”
    Thesis
  3. 283

    Secondary metabolites and transcriptomic analysis of novel pulcherrimin producer Metschnikowia persimmonesis KIOM G15050: A potent and safe food biocontrol agent by Endang Rahmat, Jae Sik Yu, Bum Soo Lee, Jiyoung Lee, Yeongjun Ban, Nam-Hui Yim, Jeong Hwan Park, Chang Ho Kang, Ki Hyun Kim, Youngmin Kang

    Published 2024-04-01
    “…Toxicity evaluation of M. persimmonesis extracts showed no harmful effects on the liver and mitochondria of zebrafish, and no potential risk of cardiotoxicity in hERG-HEK293 cell lines. Thus, M. persimmonesis can be commercialized as a potent and safe biocontrol agent for preserving food products.…”
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    Overexpression of KCNJ2 enhances maturation of human-induced pluripotent stem cell-derived cardiomyocytes by Jingjun Zhou, Baiping Cui, Xiaochen Wang, Hongkun Wang, Junnan Zheng, Fengfeng Guo, Yaxun Sun, Hangping Fan, Jiaxi Shen, Jun Su, Jue Wang, Haige Zhao, Yiquan Tang, Tingyu Gong, Ning Sun, Ping Liang

    Published 2023-04-01
    “…Notably, KCNJ2 OE iPSC-CMs exhibited enlarged cell size and more elongated and stretched shape, indicating a morphological phenotype toward structural maturation. Drug testing using hERG blocker E-4031 revealed that a more stable MDP in KCNJ2 OE iPSC-CMs allowed for obtaining significant drug response of APD prolongation in a concentration-dependent manner. …”
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