Molecular Mechanisms Of Mitragynine Inhibition On Herg1a/1b Channel by Tay, Yea Lu

“…The human ether-a-go-go-related gene 1 (hERG1) encodes the pore-forming subunit underlying cardiac rapidly delayed rectifier potassium current (IKr).…”
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High-Throughput Chemical Screening and Structure-Based Models to Predict hERG Inhibition by Shagun Krishna, Alexandre Borrel, Ruili Huang, Jinghua Zhao, Menghang Xia, Nicole Kleinstreuer

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Jazz Between the Lines: Sound Notation, Dances, and Stereotypes in Hergé’s Early Tintin Comics by Lukas Etter

“…The present essay illuminates how such encounters take shape in specific Francophone Belgian comics of the 1920s and 1930s; it consists of a close reading of musical and sound notation in Hergé’s early Aventures de Tintin albums. It departs from the observation that somebody like Hergé, with an oft-reported affinity for jazz, would shy away from making allusion to thriving dancefloors and the presence of African American musicians so central in the “white” Western European discourses of these decades. …”
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Predicting hERG repolarization power at 37°C from recordings at room temperature by Barbara B. R. Oliveira‐Mendes, Malak Alameh, Jérôme Montnach, Béatrice Ollivier, Solène Gibaud, Sylvain Feliciangeli, Florian Lesage, Flavien Charpentier, Gildas Loussouarn, Michel De Waard, Isabelle Baró

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Prognostic role of hERG1 Potassium Channels in Neuroendocrine Tumours of the Ileum and Pancreas by Jessica Iorio, Lorenzo Antonuzzo, Emanuela Scarpi, Massimo D’Amico, Claudia Duranti, Luca Messerini, Clotilde Sparano, Damiano Caputo, Daniele Lavacchi, Domenico Borzomati, Alice Antonelli, Lorenzo Nibid, Giuseppe Perrone, Alessandro Coppola, Roberto Coppola, Francesco di Costanzo, Elena Lastraioli, Annarosa Arcangeli

Subjects: “…hERG1 channel…”
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Inhibition of the hERG Potassium Channel by a Methanesulphonate-Free E-4031 Analogue by Matthew V. Helliwell, Yihong Zhang, Aziza El Harchi, Christopher E. Dempsey, Jules C. Hancox

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Improving the hERG model fitting using a deep learning-based method by Jaekyung Song, Jaekyung Song, Yu Jin Kim, Chae Hun Leem, Chae Hun Leem

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[Établissement public de la Réunion des musées nationaux et du Grand Palais des Champs-Élysées/Musée Hergé (éds.) Hergé, catalogue de l’exposition au Grand Palais] by Samuel Bidaud

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hERG-toxicity prediction using traditional machine learning and advanced deep learning techniques by Erik Ylipää, Swapnil Chavan, Maria Bånkestad, Johan Broberg, Björn Glinghammar, Ulf Norinder, Ian Cotgreave

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Experimentally Validated Pharmacoinformatics Approach to Predict hERG Inhibition Potential of New Chemical Entities by Saba Munawar, Saba Munawar, Monique J. Windley, Edwin G. Tse, Matthew H. Todd, Adam P. Hill, Jamie I. Vandenberg, Ishrat Jabeen

Subjects: “…hERG inhibitors…”
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Molecular mechanisms underlying the pilsicainide-induced stabilization of hERG proteins in transfected mammalian cells by Takeshi Onohara, MD, Ichiro Hisatome, MD, Yasutaka Kurata, MD, Peili Li, MD, Tomomi Notsu, PhD, Kumi Morikawa, PhD, Naoyuki Otani, MD, Akio Yoshida, MD, Kazuhiko Iitsuka, MD, Masaru Kato, MD, Junichiro Miake, MD, Haruaki Ninomiya, MD, Katsumi Higaki, PhD, Yasuaki Shirayoshi, PhD, Takashi Nishihara, BE, Toshiyuki Itoh, PhD, Yoshinobu Nakamura, MD, Motonobu Nishimura, MD

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hERG Blockade Prediction by Combining Site Identification by Ligand Competitive Saturation and Physicochemical Properties by Himanshu Goel, Wenbo Yu, Alexander D. MacKerell

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Rapid characterisation of hERG channel kinetics I: using an automated high-throughput system by Lei, CL, Clerx, M, Gavaghan, D, Polonchuk, L, Mirams, GR, Wang, K

“…We demonstrate its use on the Nanion SyncroPatch 384PE, a 384-well automated patch-clamp platform, by applying it to Chinese hamster ovary cells stably expressing hERG1a. From these recordings, we construct 124 cell-specific variants/parameterizations of a hERG model at 25°C. …”

Ligand-based prediction of hERG-mediated cardiotoxicity based on the integration of different machine learning techniques by Pietro Delre, Pietro Delre, Giovanna J. Lavado, Giuseppe Lamanna, Giuseppe Lamanna, Michele Saviano, Alessandra Roncaglioni, Emilio Benfenati, Giuseppe Felice Mangiatordi, Domenico Gadaleta

Subjects: “…hERG…”
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The Strength of hERG Inhibition by Erythromycin at Different Temperatures Might Be Due to Its Interacting Features with the Channels by Dongrong Cheng, Xiaofeng Wei, Yanting Zhang, Qian Zhang, Jianwei Xu, Jiaxin Yang, Junjie Yu, Antony Stalin, Huan Liu, Jintao Wang, Dian Zhong, Lanying Pan, Wei Zhao, Yuan Chen

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Parallel Recordings of Transmembrane hERG Channel Currents Based on Solvent-Free Lipid Bilayer Microarray by Ryusuke Miyata, Daisuke Tadaki, Daichi Yamaura, Shun Araki, Madoka Sato, Maki Komiya, Teng Ma, Hideaki Yamamoto, Michio Niwano, Ayumi Hirano-Iwata

Subjects: “…human <i>ether-a-go-go-</i>related gene (hERG) channel…”
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An LQT2-related mutation in the voltage-sensing domain is involved in switching the gating polarity of hERG by Zhipei Liu, Feng Wang, Hui Yuan, Fuyun Tian, Chuanyan Yang, Fei Hu, Yiyao Liu, Meiqin Tang, Meixuan Ping, Chunlan Kang, Ting Luo, Guimei Yang, Mei Hu, Zhaobing Gao, Ping Li

Subjects: “…hERG…”
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Facilitation of hERG Activation by Its Blocker: A Mechanism to Reduce Drug-Induced Proarrhythmic Risk by Kazuharu Furutani

Subjects: “…hERG channel…”
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Modelling effects of Sotalol on Action Potential morphology using a novel Markov model of the HERG channel by Brennan, T, Fink, M, Rodriguez, B, Tarassenko, L

The faint source population at 15.7 GHz – III. A high-frequency study of HERGs and LERGs by Whittam, I, Riley, J, Green, D, Jarvis, M

“…Optical spectra are used to classify 17 of the sources as high-excitation or low-excitation radio galaxies (HERGs and LERGs, respectively), for the remaining sources three other methods are used; these are optical compactness, X-ray observations and mid-infrared colour-colour diagrams. 32 sources are HERGs and 35 are LERGs while the remaining 29 sources could not be classified. …”