An Update on the Structure of hERG by Andrew Butler, Matthew V. Helliwell, Yihong Zhang, Jules C. Hancox, Christopher E. Dempsey

Subjects: “…hERG…”
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PIKfyve Sensitivity of hERG Channels by Tatsiana Pakladok, Ahmad Almilaji, Carlos Munoz, Ioana Alesutan, Florian Lang

“…Background/Aims: Human ether-a-go-go (hERG) channels contribute to cardiac repolarization and participate in the regulation of tumor cell proliferation. …”
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Dans les coulisses des aventures de Tintin by Samuel Bidaud

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An Insight into the Potassium Currents of hERG and Their Simulation by Rolando Guidelli

Subjects: “…hERG potassium channel…”
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Stimulation of HERG channel activity by β-catenin. by Carlos Munoz, Ambrish Saxena, Tatsiana Pakladok, Evgenii Bogatikov, Jan Wilmes, Guiscard Seebohm, Michael Föller, Florian Lang

“…Following inhibition of channel insertion into the cell membrane by brefeldin A (5 µM) the decay of current was similar in oocytes expressing HERG together with ß-catenin to oocytes expressing HERG alone. …”
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The effect of isoliquiritigenin on the hERG potassium channel by Mujahid, M, Wang, T, Ellory, C, Wilkins, R, Ma, Y-L

The Interaction between hERG1 and β1 Integrins Modulates hERG1 Current in Different Pathological Cell Models by Ginevra Chioccioli Altadonna, Alberto Montalbano, Jessica Iorio, Andrea Becchetti, Annarosa Arcangeli, Claudia Duranti

Subjects: “…hERG1…”
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Voltage-dependent gating of hERG potassium channels by Yen May eCheng, Tom W Claydon

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Inhibition of HERG potassium channels by celecoxib and its mechanism. by Roman V Frolov, Irina I Ignatova, Satpal Singh

“…Our aim was to examine the effects of celecoxib on hERG and other human channels critically involved in regulating human cardiac rhythm, and to explore the mechanisms of any observed effect on the hERG channels.Celecoxib inhibited the hERG, SCN5A, KCNQ1 and KCNQ1/MinK channels expressed in HEK-293 cells with IC(50)s of 6.0 µM, 7.5 µM, 3.5 µM and 3.7 µM respectively, and the KCND3/KChiP2 channels expressed in CHO cells with an IC(50) of 10.6 µM. …”
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Ion conduction through the hERG potassium channel. by Luisa Ceccarini, Matteo Masetti, Andrea Cavalli, Maurizio Recanatini

“…The inward rectifier voltage-gated potassium channel hERG is of primary importance for the regulation of the membrane potential of cardiomyocytes. …”
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Stereoselective inhibition of the hERG1 potassium channel by Liliana eSintra Grilo, Liliana eSintra Grilo, Pierre-Alain eCarrupt, Hugues eAbriel

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Lipid regulation of hERG1 channel function by Williams E. Miranda, Jiqing Guo, Haydee Mesa-Galloso, Valentina Corradi, James P. Lees-Miller, D. Peter Tieleman, Henry J. Duff, Sergei Yu. Noskov

“…Here, the authors combine molecular dynamics simulations, mutagenesis, and electrophysiology to provide mechanistic insights into how lipophilic molecules alter gating kinetics and K+ currents of hERG1.…”
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Long-chain acylcarnitines regulate the hERG channel. by Fabio Ferro, Aude Ouillé, Truong-An Tran, Pierre Fontanaud, Patrick Bois, Dominique Babuty, François Labarthe, Jean-Yves Le Guennec

“…We studied the effects of acyl-CARs on hERG, K(IR)2.1 and K(v)7.1/minK channels (channels responsible for I(KR), I(K1) and I(KS) respectively).HEK293 cells stably expressing hERG, K(IR)2.1 or Kv7.1/minK were studied using the patch clamp technique. …”
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Trafficking-deficient G572R-hERG and E637K-hERG activate stress and clearance pathways in endoplasmic reticulum. by Ying Wang, Xiaoyan Huang, Jianqing Zhou, Xi Yang, Di Li, Haiyan Mao, Huan Huan Sun, Ningsheng Liu, Jiangfang Lian

“…In this study, we investigated the role of ER chaperone proteins (Calnexin and Calreticulin) in the processing of G572R-hERG and E637K-hERG mutant proteins.pcDNA3-WT-hERG, pcDNA3-G572R-hERG and pcDNA3-E637K-hERG plasmids were transfected into U2OS and HEK293 cells. …”
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Compte rendu d’Hergé Reporter. Tintin en contexte by Cécile Vanderpelen-Diagre

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Translation Techniques and Acceptability of Onomatopoeia in Herge’s The Adventure of Tintin Comic by Inas Haninisa, Dyah Raina Purwaningsih, Raden Pujo Handoyo

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Hergé, catalogue de l'exposition au Grand Palais by Samuel Bidaud

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Computational determination of hERG-related cardiotoxicity of drug candidates by Hyang-Mi Lee, Myeong-Sang Yu, Sayada Reemsha Kazmi, Seong Yun Oh, Ki-Hyeong Rhee, Myung-Ae Bae, Byung Ho Lee, Dae-Seop Shin, Kwang-Seok Oh, Hyithaek Ceong, Donghyun Lee, Dokyun Na

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Eag and HERG potassium channels as novel therapeutic targets in cancer by Bali Anish, Shaw Robert, Sowter Heidi, Asher Viren, Khan Raheela

“…Eag and HERG are expressed in cancers of various organs and have been implicated in cell cycle progression and proliferation of cancer cells. …”
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Differential association between HERG and KCNE1 or KCNE2. by Sung Yon Um, Thomas V McDonald

“…The small proteins encoded by KCNE1 and KCNE2 have both been proposed as accessory subunits for the HERG channel. Here we report our investigation into the cell biology of the KCNE-HERG interaction. …”
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