High-throughput screening of BAM inhibitors in native membrane environment by Parthasarathi Rath, Adrian Hermann, Ramona Schaefer, Elia Agustoni, Jean-Marie Vonach, Martin Siegrist, Christian Miscenic, Andreas Tschumi, Doris Roth, Christoph Bieniossek, Sebastian Hiller

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The Evolving Landscape of Neuroscience Therapeutics: an Interplay of Multiple Modalities by Hendrik Knoetgen, Torsten Schindler, Felix F. Schumacher, Antonia F. Stepan, Alain C. Tissot, Jaclyn I. Wamsteeker Cusulin

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Racial and ethnic diversity in global neuroscience clinical trials by Loes Rutten-Jacobs, Tammy McIver, Adriana Reyes, Marta Pereira, Rachel Rosenthal, Christine T. Parusel, Kathryn R. Wagner, Rachelle Doody

“…Methods: We retrospectively reviewed the F. Hoffmann-La Roche database for global, multicenter, neuroscience clinical trials from February 2016 to February 2021 and summarized and stratified race and ethnicity distributions by clinical trial therapeutic area and by country. …”
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An Integrated Transcriptomics and Lipidomics Analysis Reveals That Ergosterol Is Required for Host Defense Against Bacterial Infection in Drosophila by Zihao Deng, Yanyang Yang, Jiazhen Luo, Biling Zhang, Jiyong Liu, Guanghou Shui, Renjie Jiao, Renjie Jiao, Chuanxian Wei

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Forensic analysis of counterfeit psychotropic drugs by Klara Dégardin, Aurélie Guillemain, Alexandra Feng, Christian Saladin, Stéphanie Paratte, Raphaël Zurbach, Tobias Mohn

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Robust Hydrogen-Bonded Organic Framework with Four-Fold Interpenetration for Adsorptive Separation of C2H6/C2H4 and Xe/Kr by Fu-An Guo, Kang Zhou, Jiaqi Liu, Hao Wang, Jing Li

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A randomized, double‐blind phase 1b study evaluating the safety, tolerability, pharmacokinetics and pharmacodynamics of the NLRP3 inhibitor selnoflast in patients with moderate to... by Barbara Klughammer, Luca Piali, Alexandra Nica, Sandra Nagel, Lorna Bailey, Christoph Jochum, Stanislav Ignatenko, Angela Bläuer, Sabrina Danilin, Pratiksha Gulati, Joanne Hayward, Petar Scepanovic, Jitao David Zhang, Satish Bhosale, Chui Fung Chong, Andreas Christ

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Quantifying mutant huntingtin protein in human cerebrospinal fluid to support the development of huntingtin-lowering therapies by Stephanie Vauleon, Katharina Schutz, Benoit Massonnet, Nanda Gruben, Marianne Manchester, Alessandra Buehler, Eginhard Schick, Lauren Boak, David J. Hawellek

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Preliminary validity of the Draw a Shape Test for upper extremity assessment in multiple sclerosis by Jennifer S. Graves, Marco Ganzetti, Frank Dondelinger, Florian Lipsmeier, Shibeshih Belachew, Corrado Bernasconi, Xavier Montalban, Johan vanBeek, Michael Baker, Christian Gossens, Michael Lindemann

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Modeling early pathophysiological phenotypes of diabetic retinopathy in a human inner blood-retinal barrier-on-a-chip by Thomas L. Maurissen, Alena J. Spielmann, Gabriella Schellenberg, Marc Bickle, Jose Ricardo Vieira, Si Ying Lai, Georgios Pavlou, Sascha Fauser, Peter D. Westenskow, Roger D. Kamm, Héloïse Ragelle

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Structure of the malaria vaccine candidate antigen CyRPA and its complex with a parasite invasion inhibitory antibody by Paola Favuzza, Elena Guffart, Marco Tamborrini, Bianca Scherer, Anita M Dreyer, Arne C Rufer, Johannes Erny, Joerg Hoernschemeyer, Ralf Thoma, Georg Schmid, Bernard Gsell, Araceli Lamelas, Joerg Benz, Catherine Joseph, Hugues Matile, Gerd Pluschke, Markus G Rudolph

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PB2377: PREDICTING CELL OF ORIGIN FROM DIGITIZED IMAGES OF HEMATOXYLIN AND EOSIN-STAINED SLIDES OF DIFFUSE LARGE B-CELL LYMPHOMAS USING A CELL-BASED DEEP-LEARNING MODEL by Anil Yuce, Jacob Gildenblat, Samaneh Abbasi-Sureshjani, Camille Laurent, Konstanty Korski

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Details Matter in Structure-based Drug Design by Bernd Kuhn, Jens-Uwe Peters, Markus G. Rudolph, Peter Mohr, Martin Stahl, Andreas Tosstorff

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Selective oxytocin receptor activation prevents prefrontal circuit dysfunction and social behavioral alterations in response to chronic prefrontal cortex activation in male rats by Philipp Janz, Frederic Knoflach, Konrad Bleicher, Sara Belli, Barbara Biemans, Patrick Schnider, Martin Ebeling, Christophe Grundschober, Madhurima Benekareddy, Madhurima Benekareddy

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445 The relationship between immune-related adverse events (irAEs) and ctDNA status: exploratory analysis from IMvigor010 by Thomas Powles, Sanjeev Mariathasan, Rajat Mohindra, G Scott Chandler, Corey Carter, Katrin Madjar, Bogdana I Balas, Laurent Essioux, Viraj Degaonkar

Architecting Nanostructured Co-BTC@GO Composites for Supercapacitor Electrode Application by Tianen Chen, Allen Yang, Wei Zhang, Jinhui Nie, Tingting Wang, Jianchao Gong, Yuanhao Wang, Yaxiong Ji

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TGFβ1 Induces Senescence and Attenuated VEGF Production in Retinal Pericytes by Dragana Avramovic, Sébastien A. Archaimbault, Alicia M. Kemble, Sabine Gruener, Mirjana Lazendic, Peter D. Westenskow

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Evolving regulatory perspectives on digital health technologies for medicinal product development by Seya Colloud, Thomas Metcalfe, Scott Askin, Shibeshih Belachew, Johannes Ammann, Ernst Bos, Timothy Kilchenmann, Paul Strijbos, Damien Eggenspieler, Laurent Servais, Chloé Garay, Athanasios Konstantakopoulos, Armin Ritzhaupt, Thorsten Vetter, Claudia Vincenzi, Francesca Cerreta

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Identifying opportunities for late-stage C-H alkylation with high-throughput experimentation and in silico reaction screening by David F. Nippa, Kenneth Atz, Alex T. Müller, Jens Wolfard, Clemens Isert, Martin Binder, Oliver Scheidegger, David B. Konrad, Uwe Grether, Rainer E. Martin, Gisbert Schneider

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Ionic Liquid Additives for Efficient and Durable Two-Step Perovskite Photovoltaic Devices by Fei Wang, Yonggui Sun, Taomiao Wang, Guo Yang, Qiannan Li, Yongjun Li, Haoran Lin, Xuejuan Wan, Gang Li, Hanlin Hu

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