S183: PHASE III RANDOMIZED, MULTICENTER, OPEN-LABEL COMMODORE 1 TRIAL: COMPARISON OF CROVALIMAB VS ECULIZUMAB IN COMPLEMENT INHIBITOR-EXPERIENCED PATIENTS WITH PAROXYSMAL NOCTURNAL... by Phillip Scheinberg, Diego Cle, John Edwards, Valentina Giai, Marek Hus, Jin Seok Kim, Cristina Barrenetxea Lekue, Zsolt Nagy, Erfan Nur, Jens Panse, Yasutaka Ueda, Mustafa Nuri Yenerel, Anita Appius, Nadiesh Balachandran, Sammy Chebon, Brittany Gentile, Simon Buatois, Austin Kulasekararaj

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Formulation mitigations for particle formation induced by enzymatic hydrolysis of polysorbate 20 in protein-based drug products: insights from a full-factorial longitudinal study by Inn H. Yuk, Theo Koulis, Nidhi Doshi, Kathrin Gregoritza, Constanze Hediger, Vanessa Lebouc-Haefliger, Jamie Giddings, Tarik A. Khan

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Effective engineering of a ketoreductase for the biocatalytic synthesis of an ipatasertib precursor by Sumire Honda Malca, Nadine Duss, Jasmin Meierhofer, David Patsch, Michael Niklaus, Stefanie Reiter, Steven Paul Hanlon, Dennis Wetzl, Bernd Kuhn, Hans Iding, Rebecca Buller

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Outcome measures based on digital health technology sensor data: data- and patient-centric approaches by Kirsten I. Taylor, Hannah Staunton, Florian Lipsmeier, David Nobbs, Michael Lindemann

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Physiologically Based Biopharmaceutics Modeling of Food Effect for Basmisanil: A Retrospective Case Study of the Utility for Formulation Bridging by Tejashree Belubbi, Davide Bassani, Cordula Stillhart, Neil Parrott

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Small molecule inhibitors for cancer immunotherapy and associated biomarkers – the current status by Lisa Schlicher, Luke G. Green, Andrea Romagnani, Florian Renner

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Changes in Spinal-Reflex Excitability during Static Stretch and/or Explosive Contraction by Kyeong Eun Min, YongSuk Lee, Jihong Park

“…To examine individual or combined effects of static stretch and explosive contraction on quadriceps spinal-reflex excitability (the peak Hoffmann’s reflex normalized by the peak motor-response) and the latency times of the Hoffmann’s reflex and motor-response. …”
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P1129: GLOFITAMAB MONOTHERAPY IN PATIENTS WITH RELAPSED/REFRACTORY (R/R) LARGE B-CELL LYMPHOMA (LBCL): EXTENDED FOLLOW-UP AND LANDMARK ANALYSES FROM A PIVOTAL PHASE II STUDY by Martin Hutchings, Carmelo Carlo-Stella, Franck Morschhauser, Michael Dickinson, Emmanuel Bachy, Guillaume Cartron, Cyrus Khan, Monica Tani, Joaquín Martinez-Lopez, Nancy L. Bartlett, Antonio Salar, Joshua Brody, Sirpa Leppa, Pauline Baumlin, Linda Lundberg, James Relf, Yuying Xie, Alessia Bottos, Kathryn Humphrey, Lorenzo Falchi

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CONHECIMENTO, COOPERAÇÃO, INSTITUIÇÕES E REPUTAÇÃO: RECURSOS RELEVANTES PARA LOCALIZAÇÃO DE EMPRESAS EM UM PARQUE TECNOLÓGICO? by Paula Karina Salume, Liliane Oliveira Guimaraes, Ângela França Versiani

“…O instrumento de coleta de dados utilizado foi o do estudo de Neckel, Hoffmann e Schoreder (2010), que adaptaram o instrumento inicialmente construído por Hoffmann (2002). …”
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Sky islands of the Cameroon Volcanic Line support the westernmost clade of five new Typoderus weevils (Coleoptera: Curculionidae: Molytinae) by Vasily V. Grebennikov

“…(the only non-nominative subgenus of Typoderus), Neoanchonidium Hoffmann, 1968 syn. nov. (subgenus of Anchonidium) and Subanchonidium Hoffmann, 1968 syn. nov. …”
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P1125: CELESTIMO: A PHASE III TRIAL EVALUATING THE EFFICACY AND SAFETY OF MOSUNETUZUMAB PLUS LENALIDOMIDE VERSUS RITUXIMAB PLUS LENALIDOMIDE IN PATIENTS WITH RELAPSED OR REFRACTORY... by L. Nastoupil, F. Morschhauser, C. W. Scholz, M. Bishton, S.-S. Yoon, P. Giri, M. C. Wei, A. Knapp, C.-C. Li, A. Bottos, H. Li, E. Purev, N. L. Bartlett

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Hybrid-control arm construction using historical trial data for an early-phase, randomized controlled trial in metastatic colorectal cancer by Chen Li, Ana Ferro, Shivani K. Mhatre, Danny Lu, Marcus Lawrance, Xiao Li, Shi Li, Simon Allen, Jayesh Desai, Marwan Fakih, Michael Cecchini, Katrina S. Pedersen, Tae You Kim, Irmarie Reyes-Rivera, Neil H. Segal, Christelle Lenain

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Disease Burden, Clinical Outcomes, and Quality of Life in People with Hemophilia A without Inhibitors in Europe: Analyses from CHESS II/CHESS PAEDs by Pratima Chowdary, Richard Ofori-Asenso, Francis Nissen, Enrico F. Grazzi, Martynas Aizenas, Katya Moreno, Tom Burke, Beatrice Nolan, Jamie O'Hara, Kate Khair

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Obinutuzumab Can Be Administered as a 90-minute Short Duration Infusion in Patients With Previously Untreated Follicular Lymphoma: GAZELLE End of Induction Analysis by Miguel A. Canales, Thomas A. Buchholz, Jaisson A.P. Bortolini, Laura M. Fogliatto, Takayuki Ishikawa, Koji Izutsu, Antonio Salar, Jeff P. Sharman, Dirk Klingbiel, Sunny Pokala, Ekaterina Vorozheikina, Peter Trask, Joana Parreira, Kai Hübel

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Editorial: Biomarkers in the era of cancer immunotherapy: zooming in from the periphery to the tumor microenvironment by Jehad Charo, Bruno Gomes, Kristian Pietras, Arne Östman

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The Clinical Development of Taldefgrobep Alfa: An Anti-Myostatin Adnectin for the Treatment of Duchenne Muscular Dystrophy by Francesco Muntoni, Barry J. Byrne, Hugh J. McMillan, Monique M. Ryan, Brenda L. Wong, Juergen Dukart, Amita Bansal, Valerie Cosson, Roxana Dreghici, Maitea Guridi, Michael Rabbia, Hannah Staunton, Giridhar S. Tirucherai, Karl Yen, Xiling Yuan, Kathryn R. Wagner, the Taldefgrobep Alfa Study Group

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Natural history of Type 1 spinal muscular atrophy: a retrospective, global, multicenter study by Claude Cances, Dmitry Vlodavets, Giacomo Pietro Comi, Riccardo Masson, Maria Mazurkiewicz-Bełdzińska, Kayoko Saito, Edmar Zanoteli, Angela Dodman, Muna El-Khairi, Ksenija Gorni, Isaac Gravestock, Janine Hoffart, Renata S. Scalco, Basil T. Darras, the ANCHOVY Working Group

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Wenn die Versorgungsforschung bedeutsam wird by Peter Stegmaier

“…„Liebe Versorgungsforscherinnen und Versorgungsforscher, endlich sind wir da, wofür wir gearbeitet haben.“ Mit diesen begeisterten Worten eröffnete Prof. Dr. Wolfgang Hoffmann, Vorsitzender des Netzwerks Versorgungsforschung (DNVF), den 22. …”
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R WE ready for reimbursement? A round up of developments in real-world evidence relating to health technology assessment: part 10 by Alex Simpson, Sreeram V Ramagopalan

Dimethylammonium Cation-Induced 1D/3D Heterostructure for Efficient and Stable Perovskite Solar Cells by Xianfang Zhou, Chuangye Ge, Xiao Liang, Fei Wang, Dawei Duan, Haoran Lin, Quanyao Zhu, Hanlin Hu

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