Carboplatin in Patients With Metastatic Castration-Resistant Prostate Cancer Harboring Somatic or Germline Homologous Recombination Repair Gene Mutations: Phase II Single-Arm Trial by Rishabh Jain, Akash Kumar, Atul Sharma, Ranjit Kumar Sahoo, Aparna Sharma, Amlesh Seth, Brusabhanu Nayak, Shamim A Shamim, Seema Kaushal, Haresh KP, Chandan J Das, Atul Batra

“… BackgroundApproximately 20%-25% of patients with metastatic castration-resistant prostate cancer (mCRPC) harbor a deleterious germline or somatic mutation in the homologous recombination repair (HRR) pathway genes, which is involved in the repair of double-stranded DNA damage. …”
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The archaeal KEOPS complex possesses a functional Gon7 homolog and has an essential function independent of the cellular t6A modification level by Pengju Wu, Qi Gan, Xuemei Zhang, Yunfeng Yang, Yuanxi Xiao, Qunxin She, Jinfeng Ni, Qihong Huang, Yulong Shen

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Genomic and metabolic instability during long-term fermentation of an industrial Saccharomyces cerevisiae strain engineered for C5 sugar utilization by Maëlle Duperray, Mathéo Delvenne, Jean Marie François, Jean Marie François, Frank Delvigne, Jean-Pascal Capp

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Genetic Manipulation in Mucorales and New Developments to Study Mucormycosis by Carlos Lax, José Tomás Cánovas-Márquez, Ghizlane Tahiri, Eusebio Navarro, Victoriano Garre, Francisco Esteban Nicolás

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Mechanism of PARP inhibitor resistance and potential overcoming strategies by Xiaoyu Fu, Ping Li, Qi Zhou, Ruyuan He, Guannan Wang, Shiya Zhu, Amir Bagheri, Gary Kupfer, Huadong Pei, Juanjuan Li

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Male breast cancer: No evidence for mosaic BRCA1 promoter methylation involvement by Mathias Schwartz, Sabrina Ibadioune, Sophie Vacher, Marie-Charlotte Villy, Olfa Trabelsi-Grati, Jessica Le Gall, Sandrine M. Caputo, Hélène Delhomelle, Mathilde Warcoin, Virginie Moncoutier, Christine Bourneix, Nadia Boutry-Kryza, Antoine De Pauw, Marc-Henri Stern, Bruno Buecher, Emmanuelle Mouret-Fourme, Chrystelle Colas, Dominique Stoppa-Lyonnet, Julien Masliah-Planchon, Lisa Golmard, Ivan Bieche

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Relevance of the MicroRNA (Mirna) Processor DICER Expression in the Biological Behaviour and Pathological Response of Nigerian Breast Cancer Tissues by Agboola A, Ebili H, Iyawe V, Banjo A, Salami B, Rakha E, Nolan C, Ellis I, Green A

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Optimized electroporation-induced transformation in Microcystis aeruginosa PCC7806 by El Semary, A.

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Neoadjuvant afatinib with paclitaxel for triple-negative breast cancer and the molecular characteristics in responders and non-responders by Po-Han Lin, Ling-Ming Tseng, Yi-Hsuan Lee, Shou-Tung Chen, Dah-Cherng Yeh, Ming-Shen Dai, Liang-Chih Liu, Ming-Yang Wang, Chiao Lo, Stanley Chang, Kien Thiam Tan, Shu-Jen Chen, Sung-Hsin Kuo, Chiun-Sheng Huang

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BRCA Mutations in Ovarian and Prostate Cancer: Bench to Bedside by Stergios Boussios, Elie Rassy, Michele Moschetta, Aruni Ghose, Sola Adeleke, Elisabet Sanchez, Matin Sheriff, Cyrus Chargari, Nicholas Pavlidis

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PARP Inhibitors in Melanoma—An Expanding Therapeutic Option? by Wei Yen Chan, Lauren J. Brown, Lee Reid, Anthony M. Joshua

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Unravelling the Role of PARP1 in Homeostasis and Tumorigenesis: Implications for Anti-Cancer Therapies and Overcoming Resistance by Taylor Lovsund, Fatemeh Mashayekhi, Amira Fitieh, James Stafford, Ismail Hassan Ismail

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Non-Recombinogenic Functions of Rad51, BRCA2, and Rad52 in DNA Damage Tolerance by Félix Prado

Subjects: “…homologous recombination…”
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FOXM1 Inhibition in Ovarian Cancer Tissue Cultures Affects Individual Treatment Susceptibility Ex Vivo by Luzie Brückner, Annika Reinshagen, Ngoc Anh Hoang, Anne Kathrin Höhn, Florian Lordick, Ingo Bechmann, Bahriye Aktas, Ivonne Nel, Sonja Kallendrusch

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Successes and challenges of PARP inhibitors in cancer therapy by Tiffany K Ricks, Haw-Jyh eChiu, Gwynn eIson, Geoffrey eKim, Amy E McKee, Paul eKluetz, Richard ePazdur

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Genetic diversity of Coffea arabica L. mitochondrial genomes caused by repeat- mediated recombination and RNA editing by Yang Ni, Xinyi Zhang, Jingling Li, Qianqi Lu, Haimei Chen, Binxin Ma, Chang Liu

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PARP Inhibitors in Advanced Prostate Cancer in Tumors with DNA Damage Signatures by Ciara S. McNevin, Karen Cadoo, Anne-Marie Baird, Stephen P. Finn, Ray McDermott

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Heterologous RNA Recombination in the Cystoviruses φ6 and φ8: A Mechanism of Viral Variation and Genome Repair by Paul Gottlieb, Aleksandra Alimova

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Lumpy Skin Disease Virus with Four Knocked Out Genes Was Attenuated In Vivo and Protects Cattle from Infection by Olga Chervyakova, Aisha Issabek, Kulyaisan Sultankulova, Arailym Bopi, Nurlan Kozhabergenov, Zamira Omarova, Ali Tulendibayev, Nurdos Aubakir, Mukhit Orynbayev

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<i>De Novo</i> Assembly and Comparative Analysis of the Complete Mitochondrial Genome of <i>Chaenomeles speciosa</i> (Sweet) Nakai Revealed the Existence of Two Structural Isomers by Pei Cao, Yuan Huang, Mei Zong, Zilong Xu

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