Homologous Recombination: A GRAS Yeast Genome Editing Tool by Beatrice Bernardi, Jürgen Wendland

Subjects: “…homologous recombination…”
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No observed effect of homologous recombination on influenza C virus evolution. by Han, G, Boni, M, Li, S

“…The occurrence of homologous recombination in influenza viruses has been under some debate recently. …”

Analysis of nucleotide synthesis and homologous recombination repair in Schizosaccharomyces pombe by Blaikley, E

“…<p>Nucleotide synthesis is a conserved and highly regulated response to DNA damage, required for the efficient repair of DNA double strand breaks (DSB) by homologous recombination (HR). This is essential to prevent loss of heterozygosity (LOH) and maintain genome stability. …”

Inference of homologous recombination in bacteria using whole-genome sequences. by Didelot, X, Lawson, D, Darling, A, Falush, D

SimBac: simulation of whole bacterial genomes with homologous recombination by Didelot, X, De Maio, N, Brown, T, Wilson, D

“…We present SimBac, a whole-genome bacterial evolution simulator that is roughly two orders of magnitude faster than previous software and includes a more general model of bacterial evolution, allowing both within- and between-species homologous recombination. Since methods modeling bacterial recombination generally focus on only one of these two modes of recombination, the possibility to simulate both allows for a general and fair benchmarking. …”

Frequent homologous recombination deficiency in high-grade endometrial carcinomas by Jonge, D, Auguste, A, Van Wijk, L, Schouten, P, Meijers, M, Ter Haar, N, Smit, V, Nout, R, Glaire, M, Church, D, Vrieling, H, Job, B, Boursin, Y, De Kroon, C, Rouleau, E, Leary, A, Vreeswijk, M, Bosse, T

“…We sought to assess the prevalence of homologous recombination deficiency (HRD) in EC and its association with histopathological and molecular characteristics.…”

Guidelines for identifying homologous recombination events in influenza A virus by Boni, M, Jong, d, van Doorn, H, Holmes, E

“…Here, we review the necessary criteria related to laboratory procedures and sample handling, bioinformatic analysis, and the known ecology and evolution of influenza viruses that need to be met in order to confirm that a homologous recombination event occurred in the history of a set of sequences. …”

Guidelines for identifying homologous recombination events in influenza A virus. by Boni, M, Jong, d, van Doorn, H, Holmes, E

“…We conclude that the presence of false positive signals in the non-IGSP data is more likely than false negatives in the IGSP data, and that given the evidence to date, homologous recombination seems to play little or no role in the evolution of influenza A viruses.…”

Characteristics of homologous recombination repair pathway genes mutation in ovarian cancers by Zongbi Yi, Min Chen, Shaoxing Sun, Chunxu Yang, Zijie Mei, Hui Yang, Qingming Xiang, Hui Qiu

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Unveiling novel RecO distant orthologues involved in homologous recombination. by Stéphanie Marsin, Aurélie Mathieu, Thierry Kortulewski, Raphaël Guérois, J Pablo Radicella

“…The generation of a RecA filament on single-stranded DNA is a critical step in homologous recombination. Two main pathways leading to the formation of the nucleofilament have been identified in bacteria, based on the protein complexes mediating RecA loading: RecBCD (AddAB) and RecFOR. …”
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Constructing founder sets under allelic and non-allelic homologous recombination by Konstantinn Bonnet, Tobias Marschall, Daniel Doerr

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Study of the homologous recombination genetic system to improve genetic transformation of wheat by A. De Bustos, R. Pérez, N. Jouve

Subjects: “…homologous recombination…”
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Homologous Recombination and Repair Functions Required for Mutagenicity during Yeast Meiosis by Liat Morciano, Renana M. Elgrabli, Drora Zenvirth, Ayelet Arbel-Eden

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Prediction of homologous recombination deficiency from cancer gene expression data by Jun Kang, Jieun Lee, Ahwon Lee, Youn Soo Lee

“…Objective Homologous recombination deficiency (HRD) is the main mechanism of tumorigenesis in some cancers. …”
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Race-Specific Genetic Profiles of Homologous Recombination Deficiency in Multiple Cancers by Yi-Wen Hsiao, Tzu-Pin Lu

Subjects: “…homologous recombination deficiency…”
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Fusing an exonuclease with Cas9 enhances homologous recombination in Pichia pastoris by Kun Zhang, Xingpeng Duan, Peng Cai, Linhui Gao, Xiaoyan Wu, Lun Yao, Yongjin J. Zhou

“…However, low homologous recombination (HR) efficiency hinders its precise and extensive genetic manipulation. …”
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Patient Assessment and Therapy Planning Based on Homologous Recombination Repair Deficiency by Wenbin Li, Lin Gao, Xin Yi, Shuangfeng Shi, Jie Huang, Leming Shi, Xiaoyan Zhou, Lingying Wu, Jianming Ying

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New RAD51 Inhibitors to Target Homologous Recombination in Human Cells by Irina S. Shkundina, Alexander A. Gall, Alexej Dick, Simon Cocklin, Alexander V. Mazin

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WIP1 Promotes Homologous Recombination and Modulates Sensitivity to PARP Inhibitors by Kamila Burdova, Radka Storchova, Matous Palek, Libor Macurek

“…Here we show that WIP1 promotes DNA repair through homologous recombination. Loss or inhibition of WIP1 delayed disappearance of the ionizing radiation-induced 53BP1 foci in S/G2 cells and promoted cell death. …”
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PCNA Unloading Is Crucial for the Bypass of DNA Lesions Using Homologous Recombination by Matan Arbel-Groissman, Batia Liefshitz, Nir Katz, Maxim Kuryachiy, Martin Kupiec

“…In contrast, SUMOylation recruits the Srs2 helicase, which prevents local homologous recombination. The Elg1 RFC-like complex plays an important role in unloading PCNA from the chromatin. …”
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