Redox regulation of RAD51 Cys319 and homologous recombination by peroxiredoxin 1 by John J. Skoko, Juxiang Cao, David Gaboriau, Myriam Attar, Alparslan Asan, Lisa Hong, Candice E. Paulsen, Hongqiang Ma, Yang Liu, Hanzhi Wu, Trey Harkness, Cristina M. Furdui, Yefim Manevich, Ciaran G. Morrison, Erika T. Brown, Daniel Normolle, Maria Spies, Michael Ashley Spies, Kate Carroll, Carola A. Neumann

Subjects: “…Homologous recombination…”
Get full text

The RECAP Test Rapidly and Reliably Identifies Homologous Recombination-Deficient Ovarian Carcinomas by Lise M. van Wijk, Sylvia Vermeulen, Matty Meijers, Manuela F. van Diest, Natalja T. ter Haar, Marthe M. de Jonge, Nienke Solleveld-Westerink, Tom van Wezel, Dik C. van Gent, Judith R. Kroep, Tjalling Bosse, Katja N. Gaarenstroom, Harry Vrieling, Maaike P. G. Vreeswijk

Subjects: Get full text

Accurate tumor purity determination is critical for the analysis of homologous recombination deficiency (HRD) by Michael Menzel, Volker Endris, Constantin Schwab, Klaus Kluck, Olaf Neumann, Susanne Beck, Markus Ball, Christian Schaaf, Stefan Fröhling, Peter Lichtner, Peter Schirmacher, Daniel Kazdal, Albrecht Stenzinger, Jan Budczies

Subjects: “…Homologous recombination deficiency…”
Get full text

Homologous Recombination Deficiency Testing for BRCA-Like Tumors: The Road to Clinical Validation by Marjolijn M. Ladan, Dik C. van Gent, Agnes Jager

“…Germline <i>BRCA</i> mutations result in homologous recombination deficiency (HRD) in hereditary breast and ovarian cancer, as well as several types of sporadic tumors. …”
Get full text

Correction: Constructing founder sets under allelic and non-allelic homologous recombination by Konstantinn Bonnet, Tobias Marschall, Daniel Doerr

Get full text

X-rays Activate Telomeric Homologous Recombination Mediated Repair in Primary Cells by Marco De Vitis, Francesco Berardinelli, Elisa Coluzzi, Jessica Marinaccio, Roderick J. O’Sullivan, Antonella Sgura

Subjects: Get full text

Exploring the Frequency of Homologous Recombination DNA Repair Dysfunction in Multiple Cancer Types by Lucy Gentles, Bojidar Goranov, Elizabeth Matheson, Ashleigh Herriott, Angelika Kaufmann, Sally Hall, Asima Mukhopadhyay, Yvette Drew, Nicola J. Curtin, Rachel L O’Donnell

Subjects: “…homologous recombination DNA repair…”
Get full text

The Great Majority of Homologous Recombination Repair-Deficient Tumors Are Accounted for by Established Causes by Paula Štancl, Nancy Hamel, Keith M. Sigel, William D. Foulkes, William D. Foulkes, William D. Foulkes, Rosa Karlić, Paz Polak

Subjects: “…homologous recombination deficiency…”
Get full text

Homologous Recombination as a Fundamental Genome Surveillance Mechanism during DNA Replication by Julian Spies, Hana Polasek-Sedlackova, Jiri Lukas, Kumar Somyajit

Subjects: Get full text

The progress and prospect of homologous recombination deficiency detection in clinical diagnosis and treatment of cancer by YU Li , SHEN Minna , JIANG Huiqin , WANG Beili , GUO Wei

Subjects: “…cancer| homologous recombination deficiency| poly (adp-ribose) polymerase inhibitor|precision therapy…”
Get full text

Homologous recombination repair deficient prostate cancer represents an immunologically distinct subtype by Sandra van Wilpe, Donjetë Simnica, Peter Slootbeek, Thomas van Ee, Samhita Pamidimarri Naga, Mark A. J. Gorris, Lieke L. van der Woude, Shabaz Sultan, Rutger H. T. Koornstra, Inge M. van Oort, Winald R. Gerritsen, Leonie I. Kroeze, Michiel Simons, Geert J. L. H. van Leenders, Mascha Binder, I. Jolanda M. de Vries, Niven Mehra

Subjects: Get full text

HEHR: Homing Endonuclease-Mediated Homologous Recombination for Efficient Adenovirus Genome Engineering by Katrin Schröer, Fatima Arakrak, Annika Bremke, Anja Ehrhardt, Wenli Zhang

Subjects: Get full text

A direct role of RNA polymerase III and RNA in DNA homologous recombination by Sijie Liu, Daochun Kong

Subjects: Get full text

A novel role for TTK in homologous recombination: implications for breast cancer radiosensitivity by Benjamin C. Chandler, Corey Speers

Subjects: Get full text

Genomic Features of Homologous Recombination Deficiency in Breast Cancer: Impact on Testing and Immunotherapy by Umer Ali, Sunitha Vungarala, Venkataswarup Tiriveedhi

Subjects: Get full text

Mutational landscape of homologous recombination‐related genes in small‐cell lung cancer by Shuo Wu, Yao Zhang, Yan Zhang, Liz‐han Chen, Hai‐feng Ouyang, Xi Xu, Ying Du, Xin‐yu Ti

Subjects: Get full text

Intrachromosomal homologous recombination between inverted amplicons on opposing Y-chromosome arms by Noordam, Michiel J., van Daalen, Saskia K. M., Skaletsky, Helen, Clark, Brian A., Macville, Merryn V., Repping, Sjoerd, Lange, Julian, Page, David C

“…Amplicons – large, nearly identical repeats in direct or inverted orientation – are abundant in the male-specific region of the human Y chromosome (MSY) and provide targets for intrachromosomal non-allelic homologous recombination (NAHR). Thus far, NAHR events resulting in deletions, duplications, inversions, or isodicentric chromosomes have been reported only for amplicon pairs located exclusively on the short arm (Yp) or the long arm (Yq). …”
Get full text
Get full text

Integrated Mimicry of B Cell Antibody Mutagenesis Using Yeast Homologous Recombination by Swers, Jeffrey Seth, Yeung, Yik Andy, Wittrup, Karl Dane

“…Keywords: east display; Affinity maturation; Homologous recombination; Receptor editing; Receptor revision; Chain shuffling; Antibody engineering; Library design…”
Get full text

The impact of age, exposure and genetics on homologous recombination at the engineered repeat sequence in mice by Wiktor-Brown, Dominika M

Get full text

Isodicentric Y Chromosomes and Sex Disorders as Byproducts of Homologous Recombination that Maintains Palindromes by Lange, Julian, Skaletsky, Helen, van Daalen, Saskia K.M., Embry, Stephanie L., Korver, Cindy M., Brown, Laura G., Oates, Robert D., Silber, Sherman, Repping, Sjoerd, Page, David C

“…Based on our findings, we propose that intrapalindrome sequence identity is maintained via noncrossover pathways of homologous recombination. DNA double-strand breaks that initiate these pathways can be alternatively resolved by crossing over between sister chromatids to form idicY chromosomes, with clinical consequences ranging from spermatogenic failure to sex reversal and Turner syndrome. …”
Get full text
Get full text