Age-adjusted association of homologous recombination genes with ovarian cancer using clinical exomes as controls by Kevin J. Arvai, Maegan E. Roberts, Rebecca I. Torene, Lisa R. Susswein, Megan L. Marshall, Zhancheng Zhang, Natalie J. Carter, Lauren Yackowski, Erica S. Rinella, Rachel T. Klein, Kathleen S. Hruska, Kyle Retterer

“…Abstract Background Genes in the homologous recombination pathway have shown varying results in the literature regarding ovarian cancer (OC) association. …”
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An Efficient Homologous Recombination-Based In Situ Protein-Labeling Method in <i>Verticillium dahliae</i> by Jie Yang, Mengran Liu, Yue Jiao, Hui-Shan Guo, Chun-Min Shan, Haiting Wang

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OsRAD51 Plays a Vital Role in Promoting Homologous Recombination in Rice Meiosis by Xiaofei Liu, Yiwei Cao, Guijie Du, Chao Zhang, Meng Xu, Zhukuan Cheng, Yi Shen, Hengxiu Yu

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Next-generation sequencing-based analysis of homologous recombination repair gene variant in ovarian cancer by Yaolin Song, Wenwen Ran, Huiqing Jia, Qin Yao, Guangqi Li, Yang Chen, Xiaonan Wang, Yujing Xiao, Mengqi Sun, Xiao Lu, Xiaoming Xing

Subjects: “…Homologous recombination repair…”
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Optical Genome Mapping: Integrating Structural Variations for Precise Homologous Recombination Deficiency Score Calculation by Nikhil Shri Sahajpal, Ashis K. Mondal, Ashutosh Vashisht, Harmanpreet Singh, Andy Wing Chun Pang, Daniel Saul, Omar Nivin, Benjamin Hilton, Barbara R. DuPont, Vamsi Kota, Natasha M. Savage, Alex R. Hastie, Alka Chaubey, Ravindra Kolhe

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Homologous recombination-mediated cloning and manipulation of genomic DNA regions using Gateway and recombineering systems by Kagale Sateesh, Yang Wen, Rozwadowski Kevin

“…</p> <p>Results</p> <p>To enable efficient cloning and manipulation of genomic DNA fragments for the purposes of gene expression and reporter-gene studies we have combined aspects of the Gateway system and a bacteriophage-based homologous recombination (i.e. recombineering) system. To apply the method for characterising plant genes we developed novel Gateway and plant transformation vectors that are of small size and incorporate selectable markers which enable efficient identification of recombinant clones. …”
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Different Patterns of Platinum Resistance in Ovarian Cancer Cells with Homologous Recombination Proficient and Deficient Background by Michela Chiappa, Federica Guffanti, Chiara Grasselli, Nicolò Panini, Alessandro Corbelli, Fabio Fiordaliso, Giovanna Damia

“…However, there are no data in the same isogenic cell system proficient and deficient in homologous recombination (HR) on platinum-acquired resistance that might unequivocally clarify the most important mechanism associated with resistance. …”
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The BRCA1/BARD1 complex recognizes pre-ribosomal RNA to facilitate homologous recombination by Duo Wu, Huang Huang, Tenglong Chen, Xiaochen Gai, Qilin Li, Chunhui Wang, Jia Yao, Yu Liu, Shang Cai, Xiaochun Yu

“…Pre-rRNA also mediates BRCA1-dependent homologous recombination, and suppression of pre-rRNA biogenesis sensitizes cells to PARP inhibitor treatment. …”
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The Elephant and the Blind Men: Making Sense of PARP Inhibitors in Homologous Recombination Deficient Tumor Cells by Silvana eDe Lorenzo, Anand ePatel, Rachel eHurley, Scott H. Kaufmann

Subjects: “…Homologous Recombination…”
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Inducing multiple nicks promotes interhomolog homologous recombination to correct heterozygous mutations in somatic cells by Akiko Tomita, Hiroyuki Sasanuma, Tomoo Owa, Yuka Nakazawa, Mayuko Shimada, Takahiro Fukuoka, Tomoo Ogi, Shinichiro Nakada

“…Although a single nick near the mutation site rarely leads to successful gene correction, additional nicks on homologous chromosomes strongly enhance gene correction efficiency via interhomolog homologous recombination (IH-HR). This process partially depends on BRCA1 and BRCA2, suggesting the existence of several distinct pathways for MN-induced IH-HR. …”
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Fluorescent detection of homologous recombination reveals the impact of genetic, physiological, and environmental factors on genomic stability by Sukup Jackson, Michelle R

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BARD1 reads H2A lysine 15 ubiquitination to direct homologous recombination by Becker, JR, Clifford, G, Bonnet, C, Groth, A, Wilson, MD, Chapman, JR

“…Protein ubiquitination at sites of DNA double-strand breaks (DSBs) by RNF168 recruits BRCA1 and 53BP11,2, which are mediators of the homologous recombination and non-homologous end joining DSB repair pathways, respectively3. …”

Ku80 plays a role in non-homologous recombination but is not required for T-DNA integration in Arabidopsis. by Gallego, M, Bleuyard, J, Daoudal-Cotterell, S, Jallut, N, White, C

“…Chromosomal breaks are repaired by homologous recombination (HR) or non-homologous end joining (NHEJ) mechanisms. …”

Homologous recombination deficiency status predicts response to platinum-based chemotherapy in Chinese patients with high-grade serous ovarian carcinoma by Zheng Feng, Di Shao, Yuhang Cai, Rui Bi, Xingzhu Ju, Dongju Chen, Chengcheng Song, Xiaojun Chen, Jin Li, Na An, Yunjin Li, Qing Zhou, Zhihui Xiu, Shida Zhu, Xiaohua Wu, Hao Wen

Subjects: “…Homologous Recombination Deficiency…”
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High-Throughput Screening of Mouse Gene Knockouts Identifies Established and Novel High Body Fat Phenotypes by Powell DR, Revelli JP, Doree DD, DaCosta CM, Desai U, Shadoan MK, Rodriguez L, Mullens M, Yang QM, Ding ZM, Kirkpatrick LL, Vogel P, Zambrowicz B, Sands AT, Platt KA, Hansen GM, Brommage R

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The Remarkable Genetics of Helicobacter pylori by Daniel Falush

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Conserved architecture of RAD51 recombinase in ruminants revealed through molecular cloning and characterization by SONIKA AHLAWAT, REKHA SHARMA, REENA ARORA, LATIKA JAISWAL, MEENU CHOPRA, PRIYANKA SHARMA, SACHINANDAN DE

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Construction of a bacteriophage-derived recombinase system in Bacillus licheniformis for gene deletion by Fang Xue, Xufan Ma, Cheng Luo, Dongliang Li, Guiyang Shi, Youran Li

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Full-length infectious clone of a low passage dengue virus serotype 2 from Brazil by Jefferson José da Silva Santos, Tereza Magalhães, José Valter Joaquim Silva Junior, Andréa Nazaré Monteiro Rangel da Silva, Marli Tenório Cordeiro, Laura Helena Vega Gonzales Gil

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Full-length infectious clone of a low passage dengue virus serotype 2 from Brazil by Jefferson José da Silva Santos, Tereza Magalhães, José Valter Joaquim Silva Junior, Andréa Nazaré Monteiro Rangel da Silva, Marli Tenório Cordeiro, Laura Helena Vega Gonzales Gil

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