Molecular Characterization of Membrane Steroid Receptors in Hormone-Sensitive Cancers by Mirco Masi, Marco Racchi, Cristina Travelli, Emanuela Corsini, Erica Buoso

“…Cancer is one of the most common causes of death worldwide, and its development is a result of the complex interaction of genetic factors, environmental cues, and aging. Hormone-sensitive cancers depend on the action of one or more hormones for their development and progression. …”
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Considering hormone-sensitive cancers as a single disease in the UK biobank reveals shared aetiology by Muktar Ahmed, Ville-Petteri Mäkinen, Anwar Mulugeta, Jisu Shin, Terry Boyle, Elina Hyppönen, Sang Hong Lee

“…Analysis of data from the UK Biobank considering multiple hormone-sensitive cancers as a single disease suggests substantial SNP-based heritability, identifying 55 variants with genome-wide significance.…”
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Use of personal care product mixtures and incident hormone-sensitive cancers in the Sister Study: A U.S.-wide prospective cohort by Che-Jung Chang, Katie M. O'Brien, Alexander P. Keil, Mandy Goldberg, Kyla W. Taylor, Dale P. Sandler, Alexandra J. White

“…Background: Personal care products (PCPs), a source of endocrine-disrupting chemical exposure, may be associated with the risk of hormone-sensitive cancers. Few studies have investigated associations for PCP use with the incidence of hormone-sensitive cancers or considered the joint effect of multiple correlated PCPs. …”
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Natural Kinase Inhibitors for the Treatment and Management of Endometrial/Uterine Cancer: Preclinical to Clinical Studies by Rajeev K. Singla, Rajeev K. Singla, Sahar Behzad, Sahar Behzad, Johra Khan, Johra Khan, Christos Tsagkaris, Rupesh K. Gautam, Rajat Goyal, Hitesh Chopra, Bairong Shen

Subjects: “…hormone-sensitive cancer…”
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Choice of treatment options for metastatic hormone-sensitive prostate cancer by R. A. Gafanov, A. G. Dzidzaria, I. B. Kravtsov, S. V. Fastovets

Subjects: “…metastatic hormone-sensitive cancer…”
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Natural Products for the Management of Castration-Resistant Prostate Cancer: Special Focus on Nanoparticles Based Studies by Rajeev K. Singla, Rajeev K. Singla, Chandragiri Siva Sai, Hitesh Chopra, Sahar Behzad, Sahar Behzad, Himangini Bansal, Rajat Goyal, Rupesh K. Gautam, Christos Tsagkaris, Shikha Joon, Shikha Joon, Shailja Singla, Bairong Shen

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Genomic Profiling of the Steroidogenic Acute Regulatory Protein in Breast Cancer: In Silico Assessments and a Mechanistic Perspective by Pulak R. Manna, Ahsen U. Ahmed, Shengping Yang, Madhusudhanan Narasimhan, Joëlle Cohen-Tannoudji, Andrzej T. Slominski, Kevin Pruitt

Subjects: “…hormone sensitive cancers…”
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Natural Product-Based Studies for the Management of Castration-Resistant Prostate Cancer: Computational to Clinical Studies by Rajeev K. Singla, Rajeev K. Singla, Pooja Sharma, Pooja Sharma, Ankit Kumar Dubey, Rohit Gundamaraju, Dinesh Kumar, Suresh Kumar, Reecha Madaan, Richa Shri, Christos Tsagkaris, Salvatore Parisi, Shikha Joon, Shikha Joon, Shailja Singla, Mohammad Amjad Kamal, Mohammad Amjad Kamal, Mohammad Amjad Kamal, Bairong Shen

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Effect of proprotein convertase subtilisin/kexin type 9 inhibition on cancer events: A pooled, post hoc, competing risk analysis of alirocumab clinical trials by Kusha A. Mohammadi, Taylor Brackin, Gregory G. Schwartz, Philippe Gabriel Steg, Michael Szarek, Garen Manvelian, Robert Pordy, Sergio Fazio, Gregory P. Geba

“…Four outcomes were evaluated: any‐neoplasm, malignant neoplasms, broad definition of hormone‐sensitive cancers, and stricter definition of hormone‐sensitive cancers. …”
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Potential role of gabapentin and extended- release gabapentin in the management of menopausal hot flashes by Yadav M, Volkar J

“…Keywords: Hot flushes, vasomotor symptoms, postmenopausal, hormone-sensitive cancer, non-hormonal therapy, gastric-retentive, Breeze…”
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Mammary epithelial cell phenotype disruption in vitro and in vivo through ERalpha36 overexpression. by Charlène Thiebaut, Clémence Chamard-Jovenin, Amand Chesnel, Chloé Morel, El-Hadi Djermoune, Taha Boukhobza, Hélène Dumond

“…Estrogen receptor alpha 36 (ERα36) is a variant of the canonical estrogen receptor alpha (ERα66), widely expressed in hormone sensitive cancer cells and whose high expression level correlates with a poor survival prognosis for breast cancer patients. …”
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Estrogen Receptors and Melanoma: A Review by Emi Dika, Annalisa Patrizi, Martina Lambertini, Nicholas Manuelpillai, Michelangelo Fiorentino, Annalisa Altimari, Manuela Ferracin, Mattia Lauriola, Enrica Fabbri, Elena Campione, Giulia Veronesi, Federica Scarfì

“…In the last three decades cutaneous melanoma has been widely investigated as a steroid hormone-sensitive cancer. Following this hypothesis, many epidemiological studies have investigated the relationship between estrogens and melanoma. …”
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Ospemifene in the Management of Vulvar and Vaginal Atrophy: Focus on the Assessment of Patient Acceptability and Ease of Use by Cagnacci A, Xholli A, Venier M

“…Hormones are mostly contraindicated in women with a history of hormone-sensitive cancer and are frequently not accepted even by women without contraindications. …”
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Identification by Molecular Docking of Homoisoflavones from Leopoldia comosa as Ligands of Estrogen Receptors by Fedora Grande, Bruno Rizzuti, Maria A. Occhiuzzi, Giuseppina Ioele, Teresa Casacchia, Fabrizio Gelmini, Rita Guzzi, Antonio Garofalo, Giancarlo Statti

“…The majority of these compounds belongs to the isoflavones family and the most representative one, genistein, shows anti-proliferative effects on various hormone-sensitive cancer cells, including breast, ovarian and prostate cancer. …”
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Hormone-Related Cancer and Autoimmune Diseases: A Complex Interplay to be Discovered by A Losada-García, SA Cortés-Ramírez, M Cruz-Burgos, M Morales-Pacheco, M Morales-Pacheco, Carlos D Cruz-Hernández, Vanessa Gonzalez-Covarrubias, Carlos Perez-Plascencia, MA Cerbón, M Rodríguez-Dorantes

“…As a result, future research should clarify the molecular pathways involved, including any causal relationships, in order to eventually allocate information that will aid in the treatment of hormone-sensitive cancer and autoimmune illness.…”
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Sex-specific outcomes in cancer therapy: the central role of hormones by Parisa Bakhshi, Jim Q. Ho, Steven Zanganeh

“…However, disparities in treatment outcomes between males and females in hormone-sensitive cancers necessitate further exploration. …”
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Efficacy and Safety of Controlled Ovarian Stimulation With or Without Letrozole Co-administration for Fertility Preservation: A Systematic Review and Meta-Analysis by Benedetta Bonardi, Benedetta Bonardi, Claudia Massarotti, Marco Bruzzone, Oranite Goldrat, Giorgia Mangili, Paola Anserini, Stefano Spinaci, Luca Arecco, Luca Arecco, Lucia Del Mastro, Lucia Del Mastro, Marcello Ceppi, Isabelle Demeestere, Isabelle Demeestere, Matteo Lambertini, Matteo Lambertini

“…Similar results were observed in the secondary analysis including only breast cancer patients.Conclusions: These findings are reassuring on the efficacy and safety of COS with gonadotropins and letrozole and are particularly important for fertility preservation in women with hormone-sensitive cancers.…”
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Estrogen Receptor Signaling in Breast Cancer by Paulina Miziak, Marzena Baran, Ewa Błaszczak, Alicja Przybyszewska-Podstawka, Joanna Kałafut, Jolanta Smok-Kalwat, Magdalena Dmoszyńska-Graniczka, Michał Kiełbus, Andrzej Stepulak

“…Estrogen receptor (ER) signaling is a critical regulator of cell proliferation, differentiation, and survival in breast cancer (BC) and other hormone-sensitive cancers. In this review, we explore the mechanism of ER-dependent downstream signaling in BC and the role of estrogens as growth factors necessary for cancer invasion and dissemination. …”
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Gender-affirming hormone therapy, mental health, and surgical considerations for aging transgender and gender diverse adults by Sean J. Iwamoto, Justine Defreyne, Christodoulos Kaoutzanis, Robert D. Davies, Kerrie L. Moreau, Micol S. Rothman

“…In this perspective review, we acknowledge the lack of data in older TGD adults and discuss considerations for evaluating cardiovascular disease, hormone-sensitive cancers, bone health and cognitive health, gender-affirming surgery, and mental health in the older TGD population on GAHT.…”
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Parity: A key measure of confounding in data-linkage studies of outcomes after medically assisted reproduction by Georgina M Chambers, Associate Professor, Christos A Venetis, Dr, Louisa R Jorm, Professor, Claire M Vajdic, Associate Professor

“…Parity is a confounder in this setting because it is associated with MAR and hormone-sensitive cancers.…”
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