Autonomous and Assisted Control for Synthetic Microbiology by Alvaro Banderas, Matthias Le Bec, Céline Cordier, Pascal Hersen

“…We propose that harnessing natural intercellular circuit topologies with robust evolved functions can help to achieve similar robust control in synthetic intercellular circuits. A “hybrid biology” approach, where robust synthetic microbes interact with natural consortia and—additionally—with external computers, could become a useful tool for health and environmental applications.…”
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Rational Design of Transcranial Current Stimulation (TCS) through Mechanistic Insights into Cortical Network Dynamics by Flavio eFrohlich, Flavio eFrohlich, Flavio eFrohlich, Flavio eFrohlich, Stephen L Schmidt, Stephen L Schmidt

“…We discuss the use of (1) hybrid biological-electronic experimental approaches to disentangle feedback interactions, (2) large-scale computer simulations for the study of weak global perturbations imposed by TCS, and (3) optogenetic manipulations informed by dynamics systems theory to probe network dynamics. …”
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Plant-Derived Type I Ribosome Inactivating Protein-Based Targeted Toxins: A Review of the Clinical Experience by David J. Flavell, Sopsamorn U. Flavell

“…Targeted toxins (TT) for cancer treatment are a class of hybrid biologic comprised of a targeting domain coupled chemically or genetically to a proteinaceous toxin payload. …”
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Assessing Phase-Change Materials as Effective Long-Term Biosensors in Limb Prosthetics by Robert Johnston, Danielle Sell, Goeran Fiedler, Anita Singh

“…Phase-change materials (PCMs) represent a promising biosensor technology that holds the potential to both detect and alter (i.e., stabilize) changes in the temperature of a hybrid biological/mechanical system, such as a prosthesis. …”
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Biological Removal of Nitrate from Drinking Water in Anoxic Bioreactor – Membrane Bioreactor Hybrid System by Faeze Yadegari, Elham Abdollahzadeh Sharghi, Merdad Adl

“…The results of this research show that hybrid biological system of anoxic bioreactor-MBR has a very good potential for removing nitrate from drinking water.…”
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Analyzing the Explanatory Power of Bionic Systems With the Minimal Cognitive Grid by Antonio Lieto, Antonio Lieto

“…In particular, the artificial replacement of part(s) of a biological system can provide i) a local functional account of that part(s) in the context of the overall functioning of the hybrid biological–artificial system and ii) global insights about the structural mechanisms of the biological elements connected to such artificial devices.…”
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Environmental remediation and biofuel production through nanoparticle stimulation of yeast by Pandit, Shalmalee(Shalmalee Dhananjay)

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Genome-wide profiling of yeast DNA:RNA hybrid prone sites with DRIP-chip. by Yujia A Chan, Maria J Aristizabal, Phoebe Y T Lu, Zongli Luo, Akil Hamza, Michael S Kobor, Peter C Stirling, Philip Hieter

“…Finally, we uncover mutant-specific differences in the DRIP profiles of a Sen1 helicase mutant, RNase H deletion mutant and Hpr1 THO complex mutant compared to wild type, suggesting different roles for these proteins in DNA:RNA hybrid biology. Our profiles of DNA:RNA hybrid prone loci provide a resource for understanding the properties of hybrid-forming regions in vivo, extend our knowledge of hybrid-mitigating enzymes, and contribute to models of antisense-mediated gene regulation. …”
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Antigen delivery format variation and formulation stability through use of a hybrid vector by Marie Beitelshees, Andrew Hill, Yi Li, Mingfu Chen, Mahmoud Kamal Ahmadi, Randall J. Smith, Jr, Stelios T. Andreadis, Pooya Rostami, Charles H. Jones, Blaine A. Pfeifer

“…A hybrid biological-biomaterial antigen delivery vector comprised of a polymeric shell encapsulating an Escherichia coli core was previously developed for in situ antigen production and subsequent delivery. …”
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Testing 3D printed biological platform for advancing simulated microgravity and space mechanobiology research by Giulia Silvani, Peta Bradbury, Carin Basirun, Christine Mehner, Detina Zalli, Kate Poole, Joshua Chou

“…Here, we developed an easy-to-use hybrid biological platform designed with the precision of 3D printing technologies combined with PDMS microfluidic fabrication processes to facilitate reliable and reproducible microgravity cellular experiments. …”
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Electrode material studies and cell voltage characteristics of the in situ water electrolysis performed in a pH-neutral electrolyte in bioelectrochemical systems by Georgy Givirovskiy, Vesa Ruuskanen, Leo S. Ojala, Michael Lienemann, Petteri Kokkonen, Jero Ahola

“…Hydrogen-oxidizing bacteria (HOB) have been shown to be promising micro-organisms for the reduction of carbon dioxide to a wide range of value-added products in bioelectrochemical systems with in situ water electrolysis of the cultivation medium, also known as a hybrid biological-inorganic systems (HBI). However, scaling up of this process requires overcoming the inherent constraints of the low energy efficiency partly associated with the pH-neutral electrolyte with low conductivity. …”
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Demineralization–remineralization dynamics in teeth and bone by Abou Neel EA, Aljabo A, Strange A, Ibrahim S, Coathup M, Young AM, Bozec L, Mudera V

“…Ensanya Ali Abou Neel,1–3 Anas Aljabo,3 Adam Strange,3 Salwa Ibrahim,3 Melanie Coathup,4 Anne M Young,3 Laurent Bozec,3 Vivek Mudera4 1Division of Biomaterials, Operative Dentistry Department, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia; 2Biomaterials Department, Faculty of Dentistry, Tanta University, Tanta, Egypt; 3Department of Biomaterials and Tissue Engineering, UCL Eastman Dental Institute, London, UK; 4UCL Institute of Orthopaedics and Musculoskeletal Sciences, Royal National Orthopaedic Hospital, Stanmore, London, UK Abstract: Biomineralization is a dynamic, complex, lifelong process by which living organisms control precipitations of inorganic nanocrystals within organic matrices to form unique hybrid biological tissues, for example, enamel, dentin, cementum, and bone. …”
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On the Logical Design of a Prototypical Data Lake System for Biological Resources by Haoyang Che, Yucong Duan

“…Due to their intrinsic traits, data lakes are thought to be ideal technologies for processing of hybrid biological resources in the format of text, image, audio, video, and structured tabular data. …”
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Harmonising metalworking fluid formulations with end-of-life biological treatment by Uapipatanakul, B

“…Here, Syntilo 9913 was used as a case study to develop a cradle-to-grave product that was biologically stable in use but amenable to sustainable hybrid biological treatment at end-of-life. The product was reverse engineered employing factorial design approach based on <em>a priori</em> knowledge of the product components. …”

RetSynth: determining all optimal and sub-optimal synthetic pathways that facilitate synthesis of target compounds in chassis organisms by Leanne S. Whitmore, Bernard Nguyen, Ali Pinar, Anthe George, Corey M. Hudson

“…Many current methods provide a single solution to this problem, but fail to provide all optimal pathways, optional sub-optimal solutions or hybrid biological/non-biological solutions. Results Here we present RetSynth, software with a novel algorithm for determining all optimal biological pathways given a starting biological chassis and target chemical. …”
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Novel 1,2,3-Triazole-sulphadiazine-ZnO Hybrids as Potent Antimicrobial Agents against Carbapenem Resistant Bacteria by Faizah S. Aljohani, Nadjet Rezki, Mohamed R. Aouad, Mohamed Hagar, Basant A. Bakr, Marwa M. Shaaban, Bassma H. Elwakil

“…Sulphadiazine-ZnO hybrids biological activity was explored in vitro and in vivo against metallo-β-lactamases (MBLs) producing <i>Klebsiella pneumoniae</i>. …”
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Impact of operational conditions on methane yield and microbial community composition during biological methanation in in situ and hybrid reactor systems by Radziah Wahid, Svein Jarle Horn

“…Results In this study, the efficiency of in situ and hybrid biological methanation (BM) for upgrading raw biogas was investigated. …”
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Remineralising Potential of Marine Skeletal Species-Perna viridis Powder Extract on Human Teeth Enamel: An In-vitro Study by Vanita Dattatraya Revankar, R Saranyan, Yadav Chakravarthy, E Manivannan, M Rajmohan

“…Introduction: Biomineralisation is a dynamic, complex, constant mechanism by which living organisms manage precipitations of inorganic nanocrystals within organic matrices to form unique hybrid biological tissues, for example, enamel, dentin, cementum, and bone. …”
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Impact of Cleaning on Membrane Performance during Surface Water Treatment: A Hybrid Process with Biological Ion Exchange and Gravity-Driven Membranes by Yaser Rasouli, Benoit Barbeau, Raphaël Maltais-Tariant, Caroline Boudoux, Dominique Claveau-Mallet

“…In this study, the hybrid biological ion exchange (BIEX) resin and gravity-driven membrane (GDM) process was employed for the treatment of coloured and turbid river water. …”
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