Cyclothymia, bipolar disorder and multiple sclerosis: A case report by M. D. P. Paz Otero, E. Lozano Bori, J. Sánchez Rodríguez, S. Puyal González, M. Fernández Fariña, F. Mayor Sanabria, A. Francos Ajona

“…This condition, for which she has been followed by psychiatry and psychology for more than ten years, consists of alternating periods of hypomania lasting weeks and phases in which frank depressive symptomatology predominates, with no phases of euthymia in between and with a predominance of severe deterioration of her functionality at both poles. …”
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Lurasidone for the treatment of bipolar depression: an evidence-based review by Deckersbach, Thilo, Widge, Alik, Franklin, Rachel, Zorowitz, Sam, Corse, Andrew

“…The essential diagnostic criterion for BD is episodes of mania or hypomania; however, the patients report that the majority of their time is spent in a depressive phase. …”
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A Brazilian version of the "Children's Interview for Psychiatric Syndromes" (ChIPS) A versão brasileira do "Children's Interview for Psychiatric Syndromes" (ChIPS) by Isabella G. S. de Souza, Maria Antonia Serra-Pinheiro, Renata Mousinho, Paulo Mattos

“…In this article, the sections of P-ChIPS referring to attention-deficit hyperactivity disorder, oppositional-defiant disorder, conduct disorder, mania/hypomania, anorexia nervosa, bulimia nervosa and psychotic disorders were translated to Brazilian Portuguese. …”
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Decreased dynamic variability of the cerebellum in the euthymic patients with bipolar disorder by Zhenzhu Chen, Zhifang Zhang, Feng Li, Lei Zhao, Qijing Bo, Yuan Zhou, Chuanyue Wang

“…Abstract Background Bipolar disorder (BD) is a complex mental illness characterized by different mood states, including depression, mania/hypomania, and euthymia. This study aimed to comprehensively evaluate dynamic changes in intrinsic brain activity by using dynamic fractional amplitude of low-frequency fluctuations (dfALFF) and dynamic degree centrality (dDC) in patients with BD euthymia or depression and healthy individuals. …”
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Reliability and validity of clinically useful depression outcome scale identifying mixed features in patients with manic episode by Xujuan Li, Yue Fei, Haichen Yang, Wenfei Li, Zhenghui Yi, Bixiu Yang, Leping Huang, Yu Wang, Binxun Jiang, Zuowei Wang

“…Spearman correlation coefficient was used to analyze the validity by comparing the correlation between CUDOS‐C and Patient Health Questionnaire‐9 (PHQ‐9), 32‐item Hypomania Checklist (HCL‐32). The score of MINI (hypo‐) manic episode with mixed features—DSM‐5 Module—Chinese version(MINI‐M‐C) ≥ 2 was considered as the gold standard of mixed features, and the receiver operating characteristic (ROC) curve analysis was used to calculate the optimal cut‐off values of CUDOS‐C score. …”
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Fluctuations in Parkinson’s disease and personalized medicine: bridging the gap with the neuropsychiatric fluctuation scale by Emmanuelle Schmitt, Bettina Debu, Anna Castrioto, Andrea Kistner, Valerie Fraix, Martine Bouvard, Elena Moro

“…In ON-medication, NpsyF consist in plus NPS, such as high mood, hypomania, and hyperactivity. Accurate identification of these NpsyF is essential to optimize the overall PD management. …”
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Sleep spindles in people with schizophrenia, schizoaffective disorders or bipolar disorders: a pilot study in a general population-based cohort by Jean-Marie Petit, Marie-Pierre F. Strippoli, Aurélie Stephan, Serateh Ranjbar, José Haba-Rubio, Geoffroy Solelhac, Raphaël Heinzer, Martin Preisig, Francesca Siclari, Kim Q. Do

“…In addition, while we could expect a gradual change in intensity of the same sleep spindle parameters through psychotic diagnoses, our results seem to indicate a more complex situation in which the frequency of sleep spindles might be more impacted by diagnoses including a history of mania or hypomania. Further studies with a larger number of participants are required to confirm these effects.…”
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ATYPICAL DEBUT OF BIPOLAR DISORDER IN AN ADOLESCENT: POST-COVID SYNDROME, PARANEOPLASTIC SYNDROME, OR SOMETHING ELSE? by I. Ezquiaga Bravo, R. M. Cámara, I. Gómez, A. Vilar, A. Rodríguez, M. T. Nascimento, S. Batlle, L. M. Martín

“…He presents repeated and self-limited episodes (maximum 3 weeks) of major depressive symptoms: autolytic ideation, hypothymia, asthenia, clinophilia, isolation, anhedonia, mutism, psychomotor retardation, lack of hygiene, hyporexia, hypersomnia; that alternates with periods of stability and with others of symptoms of hypomania (sudden improvement in mood, increased activity and plans), also lasting a few days. …”
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A diet rich in polyunsaturated fatty acids as supportive therapy in the treatment and prevention of psychotic disorders by R. Sitarz, D. Juchnowicz, K. Karakuła, A. Forma, J. Baj, J. Rog, R. Karpiński, A. Machrowska, H. Karakuła-Juchnowicz

“…Methods Literature review in PubMed, Google Scholar, and Web of Science using the keywords [psychosis] OR [psychotic] OR [schizophrenia] OR [unipolar] OR [bipolar] OR [schizoaffective] OR [depression] OR [manic] OR [hypomanic] OR [mania] OR [hypomania] OR [first episode psychosis] OR [ultra-high risk] OR [UHR] AND [polyunsaturated fatty acids] OR [PUFA] OR [prostaglandin] OR [phospholipid] OR [phospholipase A2] OR [arachidonic acid] OR [linoleic acid] OR [alpha-linolenic acid] OR [omega-3] OR [omega-6] OR [nutrition] OR [diet]. …”
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Clinicodemographic correlates of psychotic features in bipolar disorder – a multicenter study in China by Zhi-Fang Zhang, Juan Huang, Xue-Quan Zhu, Xin Yu, Hai-Chen Yang, Xiu-Feng Xu, Yi-Ru Fang, Qing-Rong Tan, Hui-Chun Li, Gang Wang, Ling Zhang

“…Compared with patients with BD P-, those with BD P + were more likely to be diagnosed with BD I and mania/hypomania/mixed polarity in the first mood episode. …”
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A single case report of STN-DBS for severe crack-cocaine dependence: double-blind ON vs. SHAM randomized controlled assessment by Florence Vorspan, Florence Vorspan, Philippe Domenech, Philippe Domenech, David Grabli, David Grabli, Jérôme Yelnik, Marine Delavest, Charles Dauré, Frank Bellivier, Frank Bellivier, Antoine Pelissolo, Antoine Pelissolo, Hayat Belaid, Christelle Baunez, Carine Karachi, Carine Karachi, Luc Mallet, Luc Mallet, Luc Mallet

“…An episode of DBS-induced hypomania occurred after several weeks of cocaine intake at stimulation parameters previously well tolerated. …”
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Machine Learning Prediction of Comorbid Substance Use Disorders among People with Bipolar Disorder by Vincenzo Oliva, Michele De Prisco, Maria Teresa Pons-Cabrera, Pablo Guzmán, Gerard Anmella, Diego Hidalgo-Mazzei, Iria Grande, Giuseppe Fanelli, Chiara Fabbri, Alessandro Serretti, Michele Fornaro, Felice Iasevoli, Andrea de Bartolomeis, Andrea Murru, Eduard Vieta, Giovanna Fico

“…The presence of AUD+SUD was positively associated with having hypomania as the first affective episode (OR = 4.34 95% CI = 1.42–13.31), and the presence of hetero-aggressive behavior (OR = 3.15 95% CI = 1.48–6.74). …”
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The broad bipolar phenotype: sampling the experience of mood, stress and mental imagery by Malik, A

“…<p>The overarching aim of this thesis was to use an experimental psychopathology approach to investigate mood, stress and mental imagery in the Broad Bipolar Phenotype (BPP), defined by the experience of elevated lifetime hypomania. Daily mood reactions to stress have been well explored in psychosis, but the limited research in BD has produced mixed findings. …”

Study of prefrontal cortex activation characteristics of patients with psychiatric disorders in verbal fluency task using functional near-infrared spectroscopy by Yang Yulu, Sun Yunyi, Xiao Hongqi, Zheng Yaozong, Wang Mei, Shen Danlin, Li Qing, Wang Daifa, Qiu Changjian, Meng Yajing

“…However， whether the patterns of prefrontal cortex activation observed by fNIRS are specific for different psychiatric disorders remains to be explored.ObjectiveTo investigate the characteristics of prefrontal cortex activation in patients with depression， anxiety disorder， bipolar disorder and schizophrenia in verbal fluency task （VFT） using fNIRS.MethodsFrom September to December 2021， 39 patients with schizophrenia， 205 patients with depressive disorder， 212 patients with anxiety disorder and 77 patients with bipolar disorder meeting the diagnostic criteria of the Diagnostic and Statistical Manual of Mental Disorders， fifth edition （DSM-5） were recruited in the outpatient and inpatient department of West China Hospital， Sichuan University. fNIRS was used to monitor the prefrontal cortex hemodynamic changes of patients under VFT， and the clinical symptoms of patients were assessed by Symptom Checklist 90 （SCL-90） and Hypomania Checklist-32 items（HCL-32）. Differences in mean oxyhemoglobin （HbO2） concentration and the initial slope from 2 to 7 second during VFT were compared among patients with different diseases， and the correlation between mean HbO2 concentration/initial slope and clinical symptoms was analyzed by partial correlation analysis.ResultsThe concentration of HbO2 in channel 4 （Z=2.828， P=0.028） and channel 6 （Z=2.912， P=0.022） in patients with depression were significantly higher than those in patients with schizophrenia. …”
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Mental health in UK Biobank – development, implementation and results from an online questionnaire completed by 157 366 participants: a reanalysis by Katrina A. S. Davis, Jonathan R. I. Coleman, Mark Adams, Naomi Allen, Gerome Breen, Breda Cullen, Chris Dickens, Elaine Fox, Nick Graham, Jo Holliday, Louise M. Howard, Ann John, William Lee, Rose McCabe, Andrew McIntosh, Robert Pearsall, Daniel J. Smith, Cathie Sudlow, Joey Ward, Stan Zammit, Matthew Hotopf

“…Operational criteria were agreed for defining likely disorder and risk states, including lifetime depression, mania/hypomania, generalised anxiety disorder, unusual experiences and self-harm, and current post-traumatic stress and hazardous/harmful alcohol use.ResultsA total of 157 366 completed online questionnaires were available by August 2017. …”
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