-
21
Non-glycosidic compounds can stimulate both human and mouse iNKT cells.
Published 2016“…Invariant natural killer T (iNKT) cells recognize CD1d/glycolipid complexes and upon activation with synthetic agonists display immunostimulatory properties. …”
Journal article -
22
Melanoma Cells Inhibit iNKT Cell Functions via PGE2 and IDO1
Published 2023-07-01Subjects: “…iNKT cells…”
Get full text
Article -
23
Towards a better understanding of human iNKT cell subpopulations for improved clinical outcomes
Published 2023-04-01Subjects: “…iNKT cell…”
Get full text
Article -
24
EARLY TREATMENT-NAIVE RHEUMATOID ARTHRITIS IS CHARACTERIZED BY QUALITATIVE CHANGES OF THE INKT REGULATORY CELL REPERTOIRE
Published 2013Conference item -
25
Parallel Session 8: Molecular and clinical interfaces of invariant natural killer T cells (iNKT)
Published 2011Conference item -
26
Lack of PD-L1 expression by iNKT cells improves the course of influenza A infection.
Published 2013-01-01“…There is evidence indicating that invariant Natural Killer T (iNKT) cells play an important role in defense against influenza A virus (IAV). …”
Get full text
Article -
27
Uhrf1 Controls iNKT Cell Survival and Differentiation through the Akt-mTOR Axis
Published 2016-04-01“…Here, we report that Uhrf1 is essential for invariant natural killer T (iNKT) cell development. We found that Uhrf1 was significantly upregulated in stage 1 iNKT cells. …”
Get full text
Article -
28
Tissue-specific metabolic profile drives iNKT cell function during obesity and liver injury
Published 2023-01-01“…Summary: Invariant natural killer T (iNKT) cells are a distinct population of lymphocytes characterized by their reactivity to glycolipids presented by CD1d. iNKT cells are found throughout the body, and little is known about their tissue-specific metabolic regulation. …”
Get full text
Article -
29
iNKT cells from patients with secondary progressive multiple sclerosis display pro-inflammatory profiles
Published 2016-11-01Subjects: Get full text
Article -
30
Insights into the heterogeneity of iNKT cells: tissue-resident and circulating subsets shaped by local microenvironmental cues
Published 2024-02-01Subjects: “…iNKT cell…”
Get full text
Article -
31
Amide analogues of CD1d agonists modulate iNKT-cell-mediated cytokine production.
Published 2012“…The prototypical iNKT cell agonist is α-galactosyl ceramide (α-GalCer). …”
Journal article -
32
Role for lysosomal phospholipase A2 in iNKT cell-mediated CD1d recognition
Published 2014“…Invariant natural killer T (iNKT) cells recognize self lipid antigens presented by CD1d molecules. …”
Journal article -
33
Differential iNKT and T Cells Activation in Non-Alcoholic Fatty Liver Disease and Drug-Induced Liver Injury
Published 2021-12-01“…Results: There was an increase in iNKT cells in NAFLD patients compared to DILI or control subjects. …”
Get full text
Article -
34
RIPK1 deficiency prevents thymic NK1.1 expression and subsequent iNKT cell development
Published 2023-10-01Subjects: Get full text
Article -
35
Vam6 reduces iNKT cell function in tumor via modulating AMPK/mTOR pathways
Published 2023-01-01Subjects: Get full text
Article -
36
CD169(+) macrophages present lipid antigens to mediate early activation of iNKT cells in lymph nodes.
Published 2010“…Invariant natural killer T cells (iNKT cells) are involved in the host defense against microbial infection. …”
Journal article -
37
Synthesis of truncated analogues of the iNKT cell agonist, α-galactosyl ceramide (KRN7000), and their biological evaluation
Published 2011“…Stimulation of iNKT cells by α-galactosyl ceramide (α-GalCer), also known as KRN7000, and its truncated analogue OCH induces both Th1- and Th2-cytokines, with OCH inducing a Th2-cytokine bias. …”
Journal article -
38
Synthesis of truncated analogues of the iNKT cell agonist, α-galactosyl ceramide (KRN7000), and their biological evaluation.
Published 2011“…Stimulation of iNKT cells by α-galactosyl ceramide (α-GalCer), also known as KRN7000, and its truncated analogue OCH induces both Th1- and Th2-cytokines, with OCH inducing a Th2-cytokine bias. …”
Journal article -
39
Commitment toward the natural T (iNKT) cell lineage occurs at the CD4+8+ stage of thymic ontogeny
Published 2005“…Similarly, introgression of a rearranged Vα14Jα18 transgene into RORγ0/0 mice results in functional iNKT cells. Thus, our data support the “T cell receptor-instructive (mainstream precursor) model” of iNKT cell lineage specification where Vα14-to-Jα18 rearrangement, positive selection, and iNKT cell lineage commitment occur at or after the DP stage of ontogeny.…”
Journal article -
40
Tnpo3 controls splicing of the pre-mRNA encoding the canonical TCR α chain of iNKT cells
Published 2023-06-01“…Abstract Unconventional T cells, such as innate natural killer T cells (iNKT) cells, are an important part of vertebrate immune defences. iNKT recognise glycolipids through a T cell receptor (TCR) that is composed of a semi-invariant TCR α chain, paired with a restricted set of TCR β chains. …”
Get full text
Article