Regeneration of invariant natural killer T (iNKT) cells: application of iPSC technology for iNKT cell-targeted tumor immunotherapy by Takahiro Aoki, Shinichiro Motohashi, Haruhiko Koseki

Subjects: “…iNKT cells…”
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The iNKT Cell–Macrophage Axis in Homeostasis and Disease by Mariana S. Cruz, José Pedro Loureiro, Maria J. Oliveira, Maria Fatima Macedo

“…Invariant natural killer T (iNKT) cells are CD1d-restricted, lipid-reactive T cells that exhibit preponderant immunomodulatory properties. …”
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New insights into iNKT cells and their roles in liver diseases by Xinyu Gu, Qingfei Chu, Xiao Ma, Jing Wang, Chao Chen, Jun Guan, Yanli Ren, Shanshan Wu, Haihong Zhu

“…Type I NKT cells are also named iNKT cells as they express a semi-invariant T cell-receptor (TCR) α chain. …”
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Modulation of Tregs and iNKT by Fingolimod in Multiple Sclerosis Patients by Diana Ferraro, Sara De Biasi, Anna Maria Simone, Riccardo Orlandi, Milena Nasi, Francesca Vitetta, Marcello Pinti, Marco Fogliani, Stefano Meletti, Andrea Cossarizza, Patrizia Sola

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Human iNKT Cells Modulate Macrophage Survival and Phenotype by J. Pedro Loureiro, Mariana S. Cruz, Ana P. Cardoso, Maria J. Oliveira, M. Fátima Macedo

Subjects: “…iNKT cells…”
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CD8+ T-cell immunity orchestrated by iNKT cells by Yingyu Qin, Xueyang Bao, Mingzhu Zheng

Subjects: “…invariant NKT (iNKT) cell…”
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iNKT cell production of GM-CSF controls Mycobacterium tuberculosis. by Alissa C Rothchild, Pushpa Jayaraman, Cláudio Nunes-Alves, Samuel M Behar

“…Invariant natural killer T (iNKT) cells are activated during infection, but how they limit microbial growth is unknown in most cases. …”
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Exploring the Therapeutic Potentials of iNKT Cells for Anti-HBV Treatment by Agnieszka Lawrenczyk, Seil Kim, Xiangshu Wen, Ran Xiong, Weiming Yuan

“…CD1d-restricted invariant NKT (iNKT) cells are a group of innate-like regulatory T cells that recognize lipid antigens. …”
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Synthetic iNKT cell-agonists as vaccine adjuvants--finding the balance. by Cerundolo, V, Barral, P, Batista, F

“…Several synthetic iNKT-cell agonists that have potential as vaccine adjuvants have been identified, but these are not without their limitations-strong agonists can lead to the undesirable effects associated with overstimulation of the immune system, whereas too weak agonists may provide insufficient iNKT cell help to stimulate maturation of dendritic cells and differentiation of B cells. …”

Characterization and Functional Analysis of Mouse Invariant Natural T (iNKT) Cells by Bezbradica, J, Stanic, A, Joyce, S

“…Invariant natural T (iNKT) cells are innate lymphocytes that recognize CD1d‐restricted lipid antigens and have immunoregulatory properties. …”

The complement system and invariant natural killer T (iNKT) cell responses by Malik, N

“…Modulation of DC effector function may in turn influence iNKT activation at the iNKT-APC interface.…”

22511 Glycolipid-loaded nanoparticles harness iNKT cells for tumor immunotherapy by Travis Shute, Elizabeth Dudley, Andrew Lai, Briana Salas, Brandy Vincent, Daniel Angel, Kelly Nash, Elizabeth Leadbetter

“…ABSTRACT IMPACT: My work is on the development of a novel tumor immunotherapy to treat various types of cancer OBJECTIVES/GOALS: As iNKT cells can have direct and indirect killing effects on tumor cells, we propose a novel strategy for activating iNKT cells, via a PLGA nanoparticle delivery platform, to promote anti-tumor immune responses. …”
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Role of CD1d and iNKT cells in regulating intestinal inflammation by Sung Won Lee, Hyun Jung Park, Luc Van Kaer, Seokmann Hong

“…Invariant natural killer T (iNKT) cells, a subset of unconventional T cells that recognize glycolipid antigens in a CD1d-dependent manner, are crucial in regulating diverse immune responses such as autoimmunity. …”
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License to Kill: When iNKT Cells Are Granted the Use of Lethal Cytotoxicity by Angélica Díaz-Basabe, Francesco Strati, Federica Facciotti

Subjects: “…iNKT…”
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Bystander activation of iNKT cells occurs during conventional T-cell alloresponses. by Jukes, J, Wood, K, Jones, N

“…It is well established that iNKT cells can be activated by both exogenous and a limited number of endogenous glycolipids. …”

Bystander activation of iNKT cells occurs during conventional T-cell alloresponses by Jukes, J, Wood, K, Jones, N

“…It is well established that iNKT cells can be activated by both exogenous and a limited number of endogenous glycolipids. …”

Perturbation of mucosal-associated invariant T cells and iNKT cells in HIV infection by Juno, J, Phetsouphanh, C, Klenerman, P, Kent, S

“…<strong>Purpose of review</strong> To analyze the possible role that the ‘unconventional’ T-cell populations mucosal-associated invariant T cell (MAIT) and iNKT cells play during HIV infection and following antiretroviral therapy (ART) treatment. …”

3502 Stimulating iNKT Cell-Mediated Neuroblastoma Cytotoxicity in a Mouse Model by Kevin Owen McNerney, Hamid Bassiri, Spyridon Karageorgos, Priya Khurana

“…OBJECTIVES/SPECIFIC AIMS: Overall Research Aim: To develop an iNKT-cell engaging reagent (“CAb”)to induce neuroblastoma-directed cytotoxicity in vitro and in a mouse model of neuroblastoma. …”
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Correction: Tissue-specific shaping of the TCR repertoire and antigen specificity of iNKT cells by Rebeca Jimeno, Marta Lebrusant-Fernandez, Christian Margreitter, Beth Lucas, Natacha Veerapen, Gurdyal S Besra, Franca Fraternali, Jo Spencer, Graham Anderson, Patricia Barral

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Expansion of highly activated iNKT cells with altered phenotype in acute dengue infection. by Kamaladasa, A, Wickramasinghe, N, Adikari, T, Gomes, L, Shyamali, N, Salio, M, Cerundolo, V, Ogg, G, Neelika Malavige, G

“…<p>Invariant natural killer T cells (iNKTs) are capable of rapid activation and production of cytokines upon recognition of antigenic lipids presented by CD1d molecules. …”