A bispecific anti-PD-1 and PD-L1 antibody induces PD-1 cleavage and provides enhanced anti-tumor activity Tekijä Diana I. Albu, Benjamin J. Wolf, Yan Qin, Xianzhe Wang, Amy Daniel Ulumben, Mei Su, Vivian Li, Eirene Ding, Jose Angel Gonzalo, Jason Kong, Ruturaj Jadhav, Nelly Kuklin, Alberto Visintin, Bing Gong, Thomas J. Schuetz

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Immuno-oncological treatment of Non-Small-Cell Lung Cancer (NSCLC) in advanced stage with Nivolumab Tekijä Fabio Venturella, Giulia Cancellieri, Marco Giammanco, Anna Maria Almerico, Igor Daniele Aleo, Anastasia Valentina Liga, Francesca Mortillaro, Irene Mistretta

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Future prospects for breast cancer immunotherapy Tekijä V. F. Semiglazov, A. I. Tseluiko, R. V. Donskikh, P. V. Krivorotko, G. A. Dashyan, V. V. Semiglazov, A. V. Komyakhov

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Deep phenotyping of surface stimulatory and inhibitory co-receptors on cancer-resident T and NK cells reveals cell subsets within the tumor-reactive CTL population that are uniquel... Tekijä James Hair, Matthew J Robinson, Robert W Wilkinson, Simon J Dovedi

Aiheet: “…Immuno-oncology…”
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A cell-engineered system to assess tumor cell sensitivity to CD8+ T cell-mediated cytotoxicity Tekijä Nadine Nelson, Marta Lopez-Pelaez, Asis Palazon, Edmund Poon, Maike De La Roche, Simon Barry, Viia Valge-Archer, Robert W. Wilkinson, Simon J. Dovedi, Paul D. Smith

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Characterising CD8+ T cell transcriptomic and clonal consequences of immune checkpoint blockade for the treatment of cancer Tekijä Watson, RA

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CYFIP2 serves as a prognostic biomarker and correlates with tumor immune microenvironment in human cancers Tekijä Qiliang Peng, Bixin Ren, Kedao Xin, Weihui Liu, Md Shahin Alam, Yinyin Yang, Xuhao Gu, Yaqun Zhu, Ye Tian

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Should We Design Clinical Trials Differently in the Era of Cancer Immunotherapy? Tekijä Chia-Chi Lin

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Thromboembolic Events Related to Treatment with Checkpoint Inhibitors: Report of Two Cases Tekijä Jessica Tsukamoto, Mariana Monteiro, Silvana Vale, Cynthia Lemos, Thais Scarpelli, Leticia Carvalho, Daniela Pezzutti, Raphael Brandão

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Epistemic dwelling: precision immuno-oncology by design Tekijä Luca Chiapperino, Nils Graber, Francesco Panese

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Mathematical modelling and transcriptional characterisation of intratumoral regulatory T cell sub-populations Tekijä Muzhingi, I

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A key to the backdoor into the castle: The clinical ramifications of immunoediting driven by antigenic competition Tekijä M. G. Hanna, Jason D. Howard

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A PDGFRB- and CD40-targeting bispecific AffiMab induces stroma-targeted immune cell activation Tekijä Alessandro Mega, Aman Mebrahtu, Gustav Aniander, Eva Ryer, Annette Sköld, Anna Sandegren, Eva Backström Rydin, Johan Rockberg, Arne Östman, Fredrik Y. Frejd

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Alternative metrics for assessing clinical benefit with immunotherapy in oncology Tekijä E. Chan, C. Quinn, I. Hirji, J. Hillengass, K. Anderson, A. Oukessou, C. Davis

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PCSK9 in Liver Cancers at the Crossroads between Lipid Metabolism and Immunity Tekijä Malak Alannan, Nabil G. Seidah, Aksam J. Merched

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Novel Immuno-oncology Therapy: Current Status of Clinical Research and Prospect of Application Tekijä Shijia ZHANG, Shengxiang REN

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Immunogenomic pathways associated with cytotoxic lymphocyte infiltration and survival in colorectal cancer Tekijä Yuanyuan Shen, Yue Guan, Justin J. Hummel, Chi-Ren Shyu, Jonathan B. Mitchem

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Innovations, challenges, and minimal information for standardization of humanized mice Tekijä Renata Stripecke, Christian Münz, Jan Jacob Schuringa, Karl‐Dimiter Bissig, Brian Soper, Terrence Meeham, Li‐Chin Yao, James P Di Santo, Michael Brehm, Estefania Rodriguez, Anja Kathrin Wege, Dominique Bonnet, Silvia Guionaud, Kristina E Howard, Scott Kitchen, Florian Klein, Kourosh Saeb‐Parsy, Johannes Sam, Amar Deep Sharma, Andreas Trumpp, Livio Trusolino, Carol Bult, Leonard Shultz

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Profile of metastatic lung cancer patients susceptible to development of thromboembolism during immunotherapy Tekijä Satoshi Endo, Takayuki Honda, Tatsuo Kawahara, Rie Sakakibara, Takahiro Mitsumura, Tsukasa Okamoto, Yasunari Miyazaki

Aiheet: “…Immuno-oncology drugs…”
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Ubiquitin-specific Protease-7 Inhibition Impairs Tip60-dependent Foxp3+ T-regulatory Cell Function and Promotes Antitumor Immunity Tekijä Liqing Wang, Suresh Kumar, Satinder Dahiya, Feng Wang, Jian Wu, Kheng Newick, Rongxiang Han, Arabinda Samanta, Ulf H. Beier, Tatiana Akimova, Tricia R. Bhatti, Benjamin Nicholson, Mathew P. Kodrasov, Saket Agarwal, David E. Sterner, Wei Gu, Joseph Weinstock, Tauseef R. Butt, Steven M. Albelda, Wayne W. Hancock

Aiheet: “…Immuno-oncology…”
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