Investigating the complex arrhythmic phenotype caused by the gain-of-function mutation KCNQ1-G229D by Zhou, X, Bueno Orovio, A, Schilling, R, Kirkby, C, Denning, C, Rajamohan, D, Burrage, K, Tinker, A, Rodriguez, B, Harmer, S

“…The mechanisms revealed in the study can potentially inform management and treatment of KCNQ1 gain-of-function mutation carriers.…”

Factors associated with severe COVID-19 in people with idiopathic inflammatory myopathy: results from the COVID-19 Global Rheumatology Alliance physician-reported registry by Carlo Alberto Scirè, Laure Gossec, Loreto Carmona, Jinoos Yazdany, Pedro M Machado, Guillermo J Pons-Estel, Christophe Richez, Marie Holmqvist, Rebecca Grainger, Jean W Liew, Emily Sirotich, Philip C Robinson, Kristin M D’Silva, Su-Ann Yeoh, Milena Gianfrancesco, Kimme L Hyrich, Lindsay Jacobsohn, Saskia Lawson-Tovey, Elsa F Mateus, Suleman Bhana, Jonathan S Hausmann, Paul Sufka, Tiffany Y-T Hsu, Arundathi Jayatilleke, Martin Schäfer, Ana Carolina de Oliveira e Silva Montandon, Paula Jordan, Samuel Katsuyuki Shinjo, Zachary Wallace, Sofía Ornella, Monique Gore-Massy, Victor R Pimentel-Quiroz, Monica Vasquez del Mercado, Edgard Torres dos Reis Neto, Laurindo Ferreira da Rocha Junior, Maria Eugenia D'Angelo Exeni, Edson Velozo

“…These findings will enable risk stratification and inform management decisions for patients with IIM.…”
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The high-volume haemodiafiltration vs high-flux haemodialysis registry trial (H4RT): a multi-centre, unblinded, randomised, parallel-group, superiority study to compare the effecti... by Fergus J. Caskey, Sunita Procter, Stephanie J. MacNeill, Julia Wade, Jodi Taylor, Leila Rooshenas, Yumeng Liu, Ammar Annaw, Karen Alloway, Andrew Davenport, Albert Power, Ken Farrington, Sandip Mitra, David C. Wheeler, Kristian Law, Helen Lewis-White, Yoav Ben-Shlomo, Will Hollingworth, Jenny Donovan, J. Athene Lane

“…Discussion This study will provide evidence of the effectiveness and cost-effectiveness of HD as compared to HDF for adults with kidney failure in-centre HD or HDF. It will inform management for this patient group in the UK and internationally. …”
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A flexible Bayesian approach for estimating survival probabilities from age‐at‐harvest data by Brett P. Skelly, Hannah L. Clipp, Stephanie M. Landry, Rich Rogers, Quinton Phelps, James T. Anderson, Christopher T. Rota

“…Although our model cannot replace more rigorous methods, we believe our model will be transformative for wildlife and fisheries practitioners who collect age‐at‐harvest data to estimate age‐ or stage‐specific survival probabilities to help inform management decisions.…”
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GBB-Nadir and KLIMA: Two Full Physics Codes for the Computation of the Infrared Spectrum of the Planetary Radiation Escaping to Space by Bianca Maria Dinelli, Samuele Del Bianco, Elisa Castelli, Alessio Di Roma, Giacomo Lorenzi, Margherita Premuda, Flavio Barbara, Marco Gai, Piera Raspollini, Gianluca Di Natale

“…In this paper, we describe two full physics codes, Geofit broadband-Nadir (GBB-Nadir) and Kyoto protocol-informed management of adaptation (KLIMA), both able to compute the OLR spectrum, while GBB-Nadir is only a forward model, and therefore computes the spectra only, KLIMA implements the computation of spectral radiance derivatives with respect to atmospheric parameters and therefore it is suitable to be used in retrieval codes. …”
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Synthesis of plant-soil feedback effects on eastern North American tree species: implications for climate-adaptive forestry by Tyler K. Refsland, Bryce Adams, Dustin Bronson, Christel C. Kern, Paula Marquardt, Amanda M. McGraw, Alejandro A. Royo, Jessica R. Miesel

“…Our synthesis of context-dependent effects of PSFs on tree performance will help inform management decisions involving assisted migration.…”
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Primed and cued: long-term acoustic telemetry links interannual and seasonal variations in freshwater flows to the spawning migrations of Common Snook in the Florida Everglades by Jordan A. Massie, Rolando O. Santos, Ryan J. Rezek, W. Ryan James, Natasha M. Viadero, Ross E. Boucek, David A. Blewett, Alexis A. Trotter, Philip W. Stevens, Jennifer S. Rehage

“…Research providing mechanistic descriptions of conditions that promote migration and reproduction can help inform management decisions aimed at conserving ecologically and economically important species.…”
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Bioassessment of multiple stressors in Afrotropical rivers: Evaluating the performance of a macroinvertebrate-based index of biotic integrity, diversity, and regional biotic indice... by Frank O. Masese, Frank O. Masese, Elizabeth W. Wanderi, Elizabeth W. Wanderi, Kobingi Nyakeya, Alfred O. Achieng, Kelly Fouchy, Michael E. McClain, Michael E. McClain

“…Thus, there is a need to develop cost-effective tools for assessing and monitoring ecological changes to inform management decisions. Studies utilizing macroinvertebrate communities as indicators of the ecological condition of streams and rivers in the Afrotropics use diverse methods, including diversity, richness, biotic and multimetric indices. …”
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Assessing giant sequoia mortality and regeneration following high‐severity wildfire by David N. Soderberg, Adrian J. Das, Nathan L. Stephenson, Marc D. Meyer, Christy A. Brigham, Joshua Flickinger

“…In total, we surveyed 5.9 ha for seedlings and assessed the crown condition of 1104 giant sequoias. To inform management, we used a statistical methodology that robustly quantifies the uncertainty in inherently “noisy” seedling data and takes advantage of readily available remote sensing metrics that would make our findings applicable to other recently burned groves. …”
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Internal control of production activity in small enterprises: domestic and international practice by Yevheniia Kaliuha, Hanna Hryshchuk

“…At the current stage of development, the internal control system of small enterprises plays an important role in ensuring the effective functioning and implementation of users' needs for information in order to make informed management decisions regarding production activities. …”
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Predicting the spatial distribution of wintering golden eagles to inform full annual cycle conservation in western North America. by Zachary P Wallace, Bryan E Bedrosian, Jeffrey R Dunk, David W LaPlante, Brian Woodbridge, Brian W Smith, Jessi L Brown, Todd M Lickfett, Katherine Gura, Dave Bittner, Ross H Crandall, Rob Domenech, Todd E Katzner, Kevin J Kritz, Stephen B Lewis, Michael J Lockhart, Tricia A Miller, Katie Quint, Adam Shreading, Steve J Slater, Dale W Stahlecker

“…Nonetheless, research aimed at mapping priority use areas to inform management of golden eagles in western North America has typically focused on territory-holding adults during the breeding period, largely to the exclusion of other seasons and life-history groups. …”
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Entrepreneurial experience and venture success: A comprehensive meta-analysis of performance determinants by Matúš Grežo, Róbert Hanák

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A comprehensive multi-state conditional occupancy model for evaluating interactions of non-native and native species by Patti J. Wohner, Paul D. Scheerer, Michael H. Meeuwig, James T. Peterson

“…Our new 2SMS occupancy model can be used by scientists and managers with a broad range of survey and covariate data to disentangle species interactions problems to help them inform management decisions.…”
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Allometric models for above-ground biomass, carbon and nutrient content of wild cherry (Prunus avium L.) trees in agroforestry systems by Zoe Schindler, Thomas Seifert, Jonathan P. Sheppard, Christopher Morhart

“…Our findings can both inform management practices in AFS and advance ecological understanding of these systems. …”
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Readmission and associated clinical factors among individuals admitted with bipolar affective disorder at a psychiatry facility in Uganda by Joan Abaatyo, Mark Mohan Kaggwa, Alain Favina, Andrew T. Olagunju

“…Future studies looking at BAD using a prospective design, standardized scales, and robust explanatory model are warranted to understand causal factors for hospital re-admission and inform management strategies.…”
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Application of continuous improvement methodologies and techniques in the Drug Design Cycle by Bucher, Ryan Michael

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The role of SNPs in the management of cancer in the broader population by Kitchen-Smith, I

“…</p> <p>The analyses presented in this thesis support previous publications indicating that common germline genetics could inform management of heterogeneity in cancer. We provide proof-of-principle that cancer-risk SNPs can uncover novel cancer biology which can in turn shape therapeutic design. …”

Factors associated with mortality in patients with COVID-19 admitted to intensive care: a systematic review and meta-analysis by Taylor, EH, Marson, EJ, Elhadi, M, Macleod, K, Yu, YC, Davids, R, Boden, R, Overmeyer, RC, Ramakrishnan, R, Thomson, DA, Coetzee, J, Biccard, BM

“…Identification of high-risk patients admitted to intensive care with COVID-19 may inform management strategies. The objective of this meta-analysis was to determine factors associated with mortality among adults with COVID-19 admitted to intensive care by searching databases for studies published between 1 January 2020 and 6 December 2020. …”

Assessment of the Spatial Variability and Uncertainty of Shreddable Pruning Biomass in an Olive Grove Based on Canopy Volume and Tree Projected Area by Antonio Rodríguez-Lizana, Alzira Ramos, María João Pereira, Amílcar Soares, Manuel Castro Ribeiro

“…The study shows that the use of prediction intervals enables the evaluation of farm areas and informed management decisions with a low level of risk. …”
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Can wrist-worn devices and a smartphone application influence arm activity in children with unilateral cerebral palsy? A proof-of-concept study by Amie Turner, Dan Jackson, Eleanor Officer, Chelsy Boyne-Nelson, Zosia Zielinska, Divya Dinraj, Jessica Blickwedel, Tom Nappey, Tom Nappey, Tim Rapley, Heather Turpin, Jill Cadwgan, Janice Elizabeth Pearse, Janice Elizabeth Pearse, Anna Purna Basu, Anna Purna Basu

“…Therapists appreciated the potential for summary patient data to inform management. Arm activity in children with UCP increased in the hour following a prompt (mean effect size z = 0.261) for the non-dominant hand, and the dominant hand (z = 0.247). …”
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