Identification of biomarkers predictive of metastasis development in early-stage colorectal cancer using network-based regularization by Carolina Peixoto, Marta B. Lopes, Marta Martins, Sandra Casimiro, Daniel Sobral, Ana Rita Grosso, Catarina Abreu, Daniela Macedo, Ana Lúcia Costa, Helena Pais, Cecília Alvim, André Mansinho, Pedro Filipe, Pedro Marques da Costa, Afonso Fernandes, Paula Borralho, Cristina Ferreira, João Malaquias, António Quintela, Shannon Kaplan, Mahdi Golkaram, Michael Salmans, Nafeesa Khan, Raakhee Vijayaraghavan, Shile Zhang, Traci Pawlowski, Jim Godsey, Alex So, Li Liu, Luís Costa, Susana Vinga

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Editorial: Altered Expression of Proteins in Cancer: Function and Potential Therapeutic Targets by João Pessoa, Marta Martins, Sandra Casimiro, Carlos Pérez-Plasencia, Varda Shoshan-Barmatz

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A new malaria vaccination tool based on replication-competent Plasmodium falciparum parasites by Diana Moita, Miguel Prudêncio

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Asymptomatic erythematous depression on the thumb by Sofia Antunes-Duarte, Rita Pimenta, Luís Soares de Almeida, Paulo Filipe

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[Artículo traducido] Dos casos de enfermedad de Darier eficazmente tratados con una combinación de retinoides orales y gel de diclofenaco sódico al 3% by P.M. Garrido, C. Queirós, L. Soares-de-Almeida, J. Borges-Costa

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Reminder: Cardiovascular Patients Also Benefit from Influenza Vaccine by Mariana Alves, Filipe Froes, Daniel Caldeira

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TrkB-ICD Fragment, Originating From BDNF Receptor Cleavage, Is Translocated to Cell Nucleus and Phosphorylates Nuclear and Axonal Proteins by João Fonseca-Gomes, João Fonseca-Gomes, André Jerónimo-Santos, André Jerónimo-Santos, Angelina Lesnikova, Plinio Casarotto, Eero Castrén, Ana M. Sebastião, Ana M. Sebastião, Maria J. Diógenes, Maria J. Diógenes

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Predictors of cardiac involvement in idiopathic inflammatory myopathies by Matilde Bandeira, Matilde Bandeira, Eduardo Dourado, Eduardo Dourado, Ana Teresa Melo, Ana Teresa Melo, Patrícia Martins, Patrícia Martins, Vanessa Fraga, José Luís Ferraro, André Saraiva, Marlene Sousa, Hugo Parente, Catarina Soares, Ana Margarida Correia, Diogo Esperança Almeida, Sara Paiva Dinis, Ana Sofia Pinto, Filipe Oliveira Pinheiro, Maria Seabra Rato, Tiago Beirão, Beatriz Samões, Bernardo Santos, Carolina Mazeda, Ana Teodósio Chícharo, Margarida Faria, Agna Neto, Maria Helena Lourenço, Luísa Brites, Marília Rodrigues, Joana Silva-Dinis, João Madruga Dias, Filipe C. Araújo, Nádia Martins, Maura Couto, Ana Valido, Maria José Santos, Maria José Santos, Sofia Carvalho Barreira, Sofia Carvalho Barreira, João Eurico Fonseca, João Eurico Fonseca, Raquel Campanilho-Marques, Raquel Campanilho-Marques

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Editorial: Cellular and molecular targets in epileptogenesis focusing on disease prevention by Diana Cunha-Reis, Diana Cunha-Reis, Diana Cunha-Reis, Sandra Henriques Vaz, Sandra Henriques Vaz, Paulo Correia-de-Sá, Paulo Correia-de-Sá

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Protocol for the isolation and culture of microglia, astrocytes, and neurons from the same mouse brain by Elvira P. Leites, Vanessa A. Morais

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Editorial: Regulatory T cells in graft versus host disease by Alfonso Rodríguez-Gil, José A. Pérez-Simón, José A. Pérez-Simón, Jerome Ritz, João F. Lacerda, João F. Lacerda, Maria VD. Soares

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A doença de alzheimer, hoje by Alexandre de Mendonça

“…Pareceu-me assim relevante, e tive muito gosto em aceitar, o honroso convite do Editor da Revista Portuguesa Clinica Geral, o meu colega de curso e amigo Mestre António Faria Vaz, para elaborar este número especial da revista, com a colaboração inestimável de vários especialistas, nomeadamente do Grupo de Demências da Faculdade de Medicina de Lisboa e Instituto de Medicina Molecular.…”
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DNA damage independent inhibition of NF-κB transcription by anthracyclines by Angelo Ferreira Chora, Dora Pedroso, Eleni Kyriakou, Nadja Pejanovic, Henrique Colaço, Raffaella Gozzelino, André Barros, Katharina Willmann, Tiago Velho, Catarina F Moita, Isa Santos, Pedro Pereira, Silvia Carvalho, Filipa Batalha Martins, João A Ferreira, Sérgio Fernandes de Almeida, Vladimir Benes, Josef Anrather, Sebastian Weis, Miguel P Soares, Arie Geerlof, Jacques Neefjes, Michael Sattler, Ana C Messias, Ana Neves-Costa, Luis Ferreira Moita

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Primary cilia contribute to the aggressiveness of atypical teratoid/rhabdoid tumors by Lena Blümel, Nan Qin, Johannes Berlandi, Eunice Paisana, Rita Cascão, Carlos Custódia, David Pauck, Daniel Picard, Maike Langini, Kai Stühler, Frauke-Dorothee Meyer, Sarah Göbbels, Bastian Malzkorn, Max C. Liebau, João T. Barata, Astrid Jeibmann, Kornelius Kerl, Serap Erkek, Marcel Kool, Stefan M. Pfister, Pascal D. Johann, Michael C. Frühwald, Arndt Borkhardt, Guido Reifenberger, Claudia C. Faria, Ute Fischer, Martin Hasselblatt, Jasmin Bartl, Marc Remke

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Molecular biomarkers associated with respiratory insufficiency in amyotrophic lateral sclerosis by Ana Catarina Pronto-Laborinho, Catarina S. Lopes, Nuno C. Santos, Filomena A. Carvalho, Mamede de Carvalho

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Glycation modulates glutamatergic signaling and exacerbates Parkinson’s disease-like phenotypes by Ana Chegão, Mariana Guarda, Bruno M. Alexandre, Liana Shvachiy, Mariana Temido-Ferreira, Inês Marques-Morgado, Bárbara Fernandes Gomes, Rune Matthiesen, Luísa V. Lopes, Pedro R. Florindo, Ricardo A. Gomes, Patrícia Gomes-Alves, Joana E. Coelho, Tiago Fleming Outeiro, Hugo Vicente Miranda

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Diagnosis and differential diagnosis of MND/ALS: IFCN handbook chapter by Mamede de Carvalho, Michael Swash

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Análise da Revisão Cochrane: O Tamanho das Porções, das Embalagens, dos Pratos e dos Copos para Alterar a Seleção e o Consumo de Alimentos, Bebidas Alcoólicas e Tabaco. Cochrane Da... by Gonçalo S. Duarte, Filipe Brogueira Rodrigues, João Costa, António Vaz-Carneiro

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The Mitochondrial Antioxidant Sirtuin3 Cooperates with Lipid Metabolism to Safeguard Neurogenesis in Aging and Depression by Sónia Sá Santos, João B. Moreira, Márcia Costa, Rui S. Rodrigues, Ana M. Sebastião, Sara Xapelli, Susana Solá

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SYNAPTIC PROTEINS IMPLICATED IN COGNITIVE VULNERABILITY by Luisa Lopes

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