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121
Cellular cartography: Towards an atlas of the neuronal microtubule cytoskeleton
Published 2023-03-01“…The polar nature of microtubules is quintessential for their function, allowing them to serve as tracks for long-distance, directed intracellular transport by kinesin and dynein motors. Most of these motors move exclusively towards either the plus- or minus-end of a microtubule and some have been shown to have a preference for either dynamic or stable microtubules, those bearing a particular post-translational modification or those decorated by a specific microtubule-associated protein. …”
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122
Cell-to-Cell Movement of Potexviruses: Evidence for a Ribonucleoprotein Complex Involving the Coat Protein and First Triple Gene Block Protein
Published 2000-09-01“…These findings are consistent with a common mode of transport for potex-viruses, involving a non-virion RNP, and show that TGBp1 is the movement protein, whereas TGBp2 and TGBp3 are either involved in intracellular transport or interact with the cellular machinery/docking sites at the plasmodesmata.…”
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123
Long-Range and Directional Allostery of Actin Filaments Plays Important Roles in Various Cellular Activities
Published 2020-05-01“…A wide variety of uniquely localized actin-binding proteins (ABPs) are involved in various cellular activities, such as cytokinesis, migration, adhesion, morphogenesis, and intracellular transport. In a micrometer-scale space such as the inside of cells, protein molecules diffuse throughout the cell interior within seconds. …”
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124
VacA’s Induction of VacA-Containing Vacuoles (VCVs) and Their Immunomodulatory Activities on Human T Cells
Published 2016-06-01“…In this review, we focus on different characteristics of VacA, its interaction with host cells, the formation and protein content of VCVs and their intracellular transport into human T cells, which finally leads to the immunosuppressive phenotype of VacA. …”
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125
Motion of a sphere and the suspending low-Reynolds-number fluid confined in a cubic cavity
Published 2022-05-01“…This work forms the basis to understand more complex dynamics in microfluidic applications such as intracellular transport and encapsulation technologies.…”
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126
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127
Lysosomes in Cancer—At the Crossroad of Good and Evil
Published 2024-03-01“…We focus on functional differences depending on lysosomal localization and the regulation of intracellular transport, and lastly provide insight how new therapeutic strategies can exploit the power of the lysosome and improve cancer treatment.…”
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128
Interactions between β-arrestin proteins and the cytoskeletal system, and their relevance to neurodegenerative disorders
Published 2023-02-01“…The cytoskeletal system plays a role in various cellular processes, including intracellular transport, cell division, organization of organelles, and cell cycle. …”
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129
Retromer-Mediated Trafficking of Transmembrane Receptors and Transporters
Published 2015-07-01“…In addition, some receptors are hijacked by exotoxins and used for entry and intracellular transport. The physiological relevance of retrograde transport cannot be overstated. …”
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130
A note on the early transcriptional response in leaves and root of potato plants to cadmium exposure
Published 2021-03-01“…These included genes involved in photosynthesis and autophagy being up-regulated, and genes involved in intracellular transport being down-regulated. This study is the first report on the transcriptome-wide response of potato to Cd stress, providing insight into the molecular mechanisms involved in the response.…”
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131
Nicotianamine: A Key Player in Metal Homeostasis and Hyperaccumulation in Plants
Published 2023-06-01“…This review summarizes the current knowledge on NA biosynthesis and its regulation, considers the mechanisms of NA secretion by plant roots, as well as the mechanisms of intracellular transport of NA and its complexes with metals, and its role in radial and long-distance metal transport. …”
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132
KIF3A tail domain phosphorylation is not required for ciliogenesis in mouse embryonic fibroblasts
Published 2024-03-01“…Heterodimeric kinesin-2 (KIF3A/KIF3B/KAP3) powers several intracellular transport processes, including intraflagellar transport (IFT), essential for ciliogenesis. …”
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133
Specifically Targeted Transport of Plasma Membrane Transporters: From Potential Mechanisms for Regulating Cell Health or Disease to Applications
Published 2021-09-01“…Secondly, the downstream receptor proteins and specific substrates of different membrane transporters were classified systematically; the functional differences of different subclasses and their relationship with intracellular transport disorders were analyzed to further explore the potential relationship between cell transport disorders and diseases. …”
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134
Automatic detection of subviral particles in fluorescence microscopy images of Marburg virus infected cells using a convolutional neural network
Published 2022-09-01“…Thereby, for the tracking of subviral particles and their intracellular transport through the cell, the detection of these particles is the first major step. …”
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135
Electro-detachment of kinesin motor domain from microtubule in silico
Published 2023-01-01“…Kinesin is a motor protein essential in cellular functions, such as intracellular transport and cell-division, as well as for enabling nanoscopic transport in bio-nanotechnology. …”
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136
Uptake of Polyelectrolyte Functionalized Upconversion Nanoparticles by Tau-Aggregated Neuron Cells
Published 2021-01-01“…It was noticed that the tau-aggregated neuron cells, when treated with relatively large sized UCNPs, showed uptake efficiency similar to that of normal neuron cells however their intracellular transport and exocytosis were impacted, and most of the carriers remained accumulated around lysosome. …”
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137
Association with BiP and aggregation of class II MHC molecules synthesized in the absence of invariant chain.
Published 1994“…We have examined the relationship between the intracellular transport and physico-chemical characteristics of various combinations of murine alpha, beta and Ii chains. …”
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138
MICAL-L1-related and unrelated mechanisms underlying elongated tubular endosomal network (ETEN) in human dendritic cells
Published 2014“… <p style="text-align:justify;"> The endosomal pathway constitutes a highly dynamic intracellular transport system, which is composed of vesicular and tubular compartments. …”
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139
Single-motor and multi-motor motility properties of kinesin-6 family members
Published 2022-10-01“…Kinesin motor proteins are responsible for orchestrating a variety of microtubule-based processes including intracellular transport, cell division, cytoskeletal organization, and cilium function. …”
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140
First-passage times in complex energy landscapes: a case study with nonmuscle myosin II assembly
Published 2022-01-01“…Complex energy landscapes often arise in biological systems, e.g. for protein folding, biochemical reactions, or intracellular transport processes. Their physical effects are frequently reflected in the first-passage times (FPTs) arising from these energy landscapes. …”
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