Correlation analysis of sperm DNA fragmentation index with semen parameters and the effect of sperm DFI on outcomes of ART by KangSheng Liu, XiaoDong Mao, Feng Pan, YaJun Chen, Ruifang An

“…In this study, we analyzed the association of sperm DNA fragmentation index (DFI) with the semen routine, sperm morphology, in vitro fertilization embryo transfer (IVF-ET)/intracytoplasmic sperm injection (ICSI). Further, we explored the predictive value of sperm DFI in evaluating male fertility and the outcome of IVF-ET/ICSI. …”
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Bioaccumulation of Non-Essential Trace Elements Detected in Women’s Follicular Fluid, Urine, and Plasma Is Associated with Poor Reproductive Outcomes following Single Euploid Embry... by Andrea Palomar, Roberto Gonzalez-Martin, Alicia Quiñonero, Nuria Pellicer, Rocio Fernandez-Saavedra, Isabel Rucandio, Rodolfo Fernandez-Martinez, Estefania Conde-Vilda, Alberto J. Quejido, Caroline Zuckerman, Christine Whitehead, Richard T. Scott, Francisco Dominguez

“…This study aims to determine the association of non-essential trace elements present in follicular fluid, plasma, and urine with reproductive outcomes of women undergoing intracytoplasmic sperm injection (ICSI), preimplantation genetic testing for aneuploidies (PGT-A) and single frozen euploid embryo transfer (SET/FET). …”
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Multidimensional morphological analysis of live sperm based on multiple-target tracking by Hao Yang, Mengmeng Ma, Xiangfeng Chen, Guowu Chen, Yi Shen, Lijun Zhao, Jianfeng Wang, Feifei Yan, Difeng Huang, Huijie Gao, Hao Jiang, Yuqian Zheng, Yu Wang, Qian Xiao, Ying Chen, Jian Zhou, Jie Shi, Yi Guo, Bo Liang, Xiaoming Teng

“…This study realized the automated detection of progressive motility and morphology of sperm simultaneously, which is crucial for selection of morphologically normal and motile sperm for intracytoplasmic sperm injection.…”
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Efficacy of three COS protocols and predictability of AMH and AFC in women with discordant ovarian reserve markers: a retrospective study on 19,239 patients by Yaxin Guo, Huahua Jiang, Shiqiao Hu, Shuai Liu, Fei Li, Lei Jin

“…Methods 19,239 patients undergoing their first fresh in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) cycles with GnRH antagonist protocols, GnRH-a long protocols or GnRH-a ultra-long protocols between January 1, 2016, and December 31, 2019, were enrolled and then divided into four groups in accordance with the boundaries for the AFC and serum AMH level provided by the Poseidon Classification. …”
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Oocyte degeneration in a cohort adversely affects clinical outcomes in conventional IVF cycles: a propensity score matching study by Lanlan Liu, Lanlan Liu, Xiaoming Jiang, Zhenfang Liu, Jinghua Chen, Chao Yang, Kaijie Chen, Xiaolian Yang, Jiali Cai, Jiali Cai, Jianzhi Ren

“…BackgroundOocyte degeneration was mostly described in intracytoplasmic sperm injection (ICSI) cycles; there is no report showing the relationship between oocyte degeneration and clinical outcomes in conventional in vitro fertilization (IVF) cycles. …”
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The Molecular Quality and Mitochondrial Activity of Porcine Cumulus–Oocyte Complexes Are Affected by Their Exposure to Three Endocrine-Active Compounds under 3D In Vitro Maturation... by Gabriela Gorczyca, Kamil Wartalski, Marek Romek, Marcin Samiec, Małgorzata Duda

“…Summing up, Vnz, Ndn and CsA reduced not only the processes of growth and IVM but also the MQ of porcine COCs, which might make them unsuitable for assisted reproductive technologies (ARTs) such as in vitro fertilization by either gamete co-incubation or intracytoplasmic sperm injection (ICSI) and cloning by somatic cell nuclear transfer (SCNT).…”
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Non-invasive preimplantation genetic testing for conventional IVF blastocysts by Pingyuan Xie, Shuoping Zhang, Yifang Gu, Bo Jiang, Liang Hu, Yue-qiu Tan, Yaxin Yao, Yi Tang, Anqi Wan, Sufen Cai, Yangyun Zou, Guangxiu Lu, Cheng Wan, Fei Gong, Sijia Lu, Ge Lin

“…Abstract Background Previous studies suggested that non-invasive preimplantation genetic testing (niPGT) for intracytoplasmic sperm injection (ICSI) blastocysts can be used to identify chromosomal ploidy and chromosomal abnormalities. …”
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Loss of ACTL7A causes small head sperm by defective acrosome-acroplaxome-manchette complex by Yini Zhang, Jianan Tang, Xuemei Wang, Yisi Sun, Tianying Yang, Xiaorong Shen, Xinyue Yang, Huijuan Shi, Xiaoxi Sun, Aijie Xin

“…The expression levels of key proteins in the pathway were analyzed by western blotting. Intracytoplasmic sperm injection (ICSI)-artificial oocyte activation (AOA) technology was utilized to overcome fertilization failure in male mice with a complete knockout of Actl7a. …”
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The Use of Assisted Reproductive Technology by European Childhood Cancer Survivors by Anja Borgmann-Staudt, Simon Michael, Greta Sommerhaeuser, Marta-Julia Fernández-González, Lucía Alacán Friedrich, Stephanie Klco-Brosius, Tomas Kepak, Jarmila Kruseova, Gisela Michel, Anna Panasiuk, Sandrin Schmidt, Laura Lotz, Magdalena Balcerek

“…Successful pregnancies were achieved after a median of one cycle with, most commonly, <i>intracytoplasmic sperm injection</i> (ICSI) using non-cryopreserved oocytes/sperm. …”
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Morfologia do primeiro corpúsculo polar e taxas de fertilização, clivagem e qualidade embrionária First polar body morphology and fertilization rate, cleavage rate, and embryo qual... by Maria Cristina Picinato Medeiros de Araújo, Carlos Henrique Medeiros de Araújo, Marcelo Gondim Rocha, Wellington de Paula Martins, Rosana Maria dos Reis, Rui Alberto Ferriani, Paula Andrea de Albuquerque Salles Navarro

“…<br>PURPOSE: to determine the relationship between the morphology of the first spindle pole of human oocytes and rates of fertilization, fragmentation and embryo quality in procedures of Intracytoplasmic Sperm Injection (ICSI). METHODS: retrospective study of 582 consecutive ICSI cycles, from July 2003 to July 2005. …”
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Exploring the efficacy and beneficial population of preimplantation genetic testing for aneuploidy start from the oocyte retrieval cycle: a real-world study by Shujuan Ma, Jingnan Liao, Shuoping Zhang, Xiaoyi Yang, Berthold Hocher, Jing Tan, Yueqiu Tan, Liang Hu, Fei Gong, Pingyuan Xie, Ge Lin

“…PGT-A (PGT-A group) and intracytoplasmic sperm injection (ICSI)/IVF (non-PGT-A group) cycles were included. …”
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Impact of COVID-19 convalescence on pregnancy outcomes in patients undergoing IVF/ICSI during fresh ART cycles: a retrospective cohort study by Mingya Cao, Yan Han, Tengfei Feng, Peiyang Lu, Yue Wang, Qingyun Sun, Zhiming Zhao, Wensen Pan

“…However, smooth curve-fitting and threshold effect analysis revealed an age-related decline in clinical pregnancy rates in both groups, more pronounced in the COVID-19 group, for women aged over 38 years, with the likelihood of clinical pregnancy decreasing by 53% with each additional year of age (odds ratio [OR] = 0.81, 95% confidence interval [CI] = 0.61–1.08, P=0.1460; odds ratio [OR] = 0.47, 95% CI = 0.21–1.05, P=0.0647).ConclusionsOur findings present no substantial evidence of adverse effects on clinical pregnancy outcomes in fresh ART cycles in patients undergoing in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) during the period of convalescence from COVID-19. …”
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Identification of zona pellucida defects revealed a novel loss-of-function mutation in ZP2 in humans and rats by Jun Zeng, Ying Sun, Jing Zhang, Xiaozhu Wu, Yan Wang, Ruping Quan, Wanjuan Song, Dan Guo, Shengran Wang, Jianlin Chen, Hongmei Xiao, Hongmei Xiao, Hua-Lin Huang

“…Immunofluorescence (IF) and intracytoplasmic sperm injection (ICSI) were used in the mutant oocytes. …”
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Avaliação de anomalias meióticas de oócitos em pacientes com síndrome dos ovários policísticos submetidas à estimulação ovariana Evaluation of meiotic abnormalities of oocytes from... by Rodolpho Cruz Vieira, Ionara Diniz Evangelista Santos Barcelos, Elisa Melo Ferreira, Maria Cristina Picinato Medeiros de Araújo, Rosana Maria dos Reis, Rui Alberto Ferriani, Paula Andrea de Albuquerque Salles Navarro

“…METHODS: five infertile patients with PCOS and eight controls, submitted to stimulated cycles for intracytoplasmic sperm injection, were selected prospectively and consecutively, and respectively assigned to the study group and the Control Group. …”
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Analysis of cumulative live birth rate and perinatal outcomes in young patients with low anti-müllerian hormone levels using two ovulation promotion protocols: A cohort study by Zhen Li, Ruolin Jia, Kexin Wang, Junwei Zhang, Bingnan Ren, Yichun Guan

“…A total of 798 cycles of complete clinical data from patients who underwent in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) at the Reproductive Medicine Center of Zhengzhou University Hospital between January 2015 and December 2020 and were eligible for AMH &lt; 1.2 ng/ml at age &lt; 35 years, Group A1: very low AMH levels (AMH &lt; 0.5 ng/mL) and GnRH antagonist regimen; Group A2, very low AMH level (AMH &lt; 0.5 ng/mL) and PPOS regimen; Group B1, low AMH level (0.5 ng/mL ≤ AMH &lt; 1.2 ng/mL) and GnRH antagonist regimen; and Group B2, low AMH level (0.5 ng/mL ≤ AMH &lt; 1.2 ng/mL), and the PPOS regimen.ResultsAt very low levels of AMH (&lt; 0.5 ng/mL), the CLBR of the GnRH antagonist regimen was not significantly different from that of the PPOS regimen (P &gt; 0.05), at 0.5 ng/mL ≤ AMH &lt; 1.2 ng/mL. …”
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hsa-miR-320a-3p and hsa-miR-483-5p levels in human granulosa cells: promising bio-markers of live birth after IVF/ICSI by Yu Liu, Qiaojuan Mei, Jiahao Yang, Qiuzi Shen, Min Zou, Jiao Li, Huaibiao Li, Ling Zhang, Wenpei Xiang

“…Methods We collected 195 granulosa cells samples and analyzed the treatment outcomes in patients undergoing in vitro fertilization (n = 147) or intracytoplasmic sperm injection (n = 48) cycles. The hsa-miR-320a-3p and hsa-miR-483-5p levels in granulosa cells were measured using quantitative reverse transcription-polymerase chain reaction. …”
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Analysis of risk factors for recurrence in infertile endometrial cancer patients after in vitro fertilization treatment by Hongyi Wei, Hongyi Wei, Ningning Pan, Ningning Pan, Ningning Pan, Ningning Pan, Yang Wang, Yang Wang, Yang Wang, Yang Wang, Caihong Ma, Caihong Ma, Caihong Ma, Caihong Ma

“…PurposeTo investigate the oncologic outcomes of patients with early-stage endometrioid endometrial cancer (EEC) treated with in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) following fertility-sparing treatment (FST).MethodsA total of 62 patients who underwent IVF/ICSI treatment in a single fertility center between June 2010 and December 2021 after conservative treatment for early-stage EEC were assigned to a recurrence group and a non-recurrence group. …”
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Genetic contributory factors to infertility by Raberi, A

“…When the semen quality is suboptimal, the intracytoplasmic sperm injection (ICSI) technique is suggested as a standard strategy to improve the prognosis of ART. …”

Potential effects of assisted reproductive technology upon the abundance and localisation of two vital sperm proteins by Yelumalai, S, Dr Suseela Yelumalai

“…<p>Assisted reproductive technology (ART) uses advanced techniques such as in vitro fertilisation (IVF) and intracytoplasmic sperm injection (ICSI) to combat human infertility. …”

Prevalence of Human Papillomavirus Infection in the Female Partner of Infertile Couples Undergoing IVF/ICSI-ET and Subsequent Reproductive Outcomes by Sanhua Wei, Kaili Wang, Fang Cheng, Zhenhua Chang, Xiaoyan Ren, Zheng Liu, Mengxin Liu, Tao Yang, Xuhui Ma, Xiaojuan Xie, Xiaohong Wang

“…We investigated the prevalence of human papillomavirus (HPV) infection in the female partner of infertile couples and the reproductive outcomes after in vitro fertilization/intracytoplasmic sperm injection-embryo transfer (IVF/ICSI-ET). …”
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