The Interplay between Drivers of Erythropoiesis and Iron Homeostasis in Rare Hereditary Anemias: Tipping the Balance by Simon Grootendorst, Jonathan de Wilde, Birgit van Dooijeweert, Annelies van Vuren, Wouter van Solinge, Roger Schutgens, Richard van Wijk, Marije Bartels

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The Mechanisms of Ferroptosis and the Applications in Tumor Treatment: Enemies or Friends? by Shuzheng Tan, Shuzheng Tan, Ying Kong, Yongtong Xian, Pengbo Gao, Yue Xu, Chuzhong Wei, Peixu Lin, Weilong Ye, Zesong Li, Xiao Zhu

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Link between Genotype and Multi-Organ Iron and Complications in Children with Transfusion-Dependent Thalassemia by Antonella Meloni, Laura Pistoia, Paolo Ricchi, Maria Caterina Putti, Maria Rita Gamberini, Liana Cuccia, Giuseppe Messina, Francesco Massei, Elena Facchini, Riccardo Righi, Stefania Renne, Giuseppe Peritore, Vincenzo Positano, Filippo Cademartiri

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The role of magnetic resonance imaging in the evaluation of thalassemic syndromes: current practice and future perspectives by Sophie Mavrogeni, George Markousis-Mavrogenis, Genovefa Kolovou

Subjects: “…thalassemia major, magnetic resonance imaging, iron overload.…”
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Association between Iron Intake and Progression of Knee Osteoarthritis by Limin Wu, Haibo Si, Yi Zeng, Yuangang Wu, Mingyang Li, Yuan Liu, Bin Shen

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Pharmacological Prevention of Ectopic Erythrophagocytosis by Cilostazol Mitigates Ferroptosis in NASH by Joon Beom Park, Kangeun Ko, Yang Hyun Baek, Woo Young Kwon, Sunghwan Suh, Song-Hee Han, Yun Hak Kim, Hye Young Kim, Young Hyun Yoo

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Contemporary non-invasive methods for the diagnosis of early cardiac dysfunction in young patients with beta-thalassemia major by Kalina Ganeva, Petar Shivachev

Subjects: “…cardiomyopathy due to iron overload…”
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Long-Term Neuroradiological and Clinical Evaluation of NBIA Patients Treated with a Deferiprone Based Iron-Chelation Therapy by Nicola Romano, Giammarco Baiardi, Valeria Maria Pinto, Sabrina Quintino, Barbara Gianesin, Riccardo Sasso, Andrea Diociasi, Francesca Mattioli, Roberta Marchese, Giovanni Abbruzzese, Antonio Castaldi, Gian Luca Forni

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A study on ECG and cardiac functional changes in patients with B-thalassemia major by Randa M Darwish, Omnia S El-Din, Ahmed Khamis

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Comparative efficacy, safety, and cost of iron chelation monotherapy vs. combination therapy in pediatric beta-thalassemia major: a single-center retrospective study by Dewi Sharon Simorangkir, Nafrialdi Nafrialdi, Pustika Amalia Wahidiyat, Vivian Soetikno

Subjects: “…thalassemia; children; iron overload; chelation agents; cost…”
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S120: RANDOMIZED CONTROLLED TRIAL OF THE EFFICACY AND SAFETY OF DEFERIPRONE: SUBGROUP ANALYSIS OF PEDIATRIC PATIENTS IN IRON-OVERLOADED PATIENTS WITH SICKLE CELL DISEASE AND OTHER ANEMIAS by B Inusa, M Hamdy, A El-Beshlawy, F Ebeid, J Kwiatkowski, J Kanter, S Williams, D Lee, N Temin, C Fradette, F Tricta, M Elalfy

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S281: TMPRSS6 INHIBITION WITH A MONOCLONAL ANTIBODY IMPROVES RED BLOOD CELL HEALTH AND IRON OVERLOAD IN A MOUSE MODEL OF BETA-THALASSEMIA by Heinrich Lob, Larisa Ivanova, Beth Crowell, Hyonjung Kim, Harvey Chin, Vincent Idone, Aris Economides, Sarah Hatsell

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SLN124, a GalNAc-siRNA Conjugate Targeting TMPRSS6, Efficiently Prevents Iron Overload in Hereditary Haemochromatosis Type 1 by Sandro Altamura, Ute Schaeper, Sibylle Dames, Kathrin Löffler, Mona Eisermann, Christian Frauendorf, Katja Müdder, Joana Neves, Martina U. Muckenthaler

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Association of iron overload based quantitative T2* MRI technique and carotid intima-media thickness in patients with beta-thalassemia: A cross-sectional study by Jafarisepehr Amirhosein, Hoseini Morteza, Akhlaghpoor Shahram

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Cardiac iron overload evaluation in thalassaemic patients using T2* magnetic resonance imaging following chelation therapy: a multicentre cross-sectional study by Eduardo Cerello Chapchap, Murilo Marques Almeida Silva, Reijane Alves de Assis, Lucila Nassif Kerbauy, Michelli da Silva Diniz, Laércio Alberto Rosemberg, Sandra Regina Loggetto, Aderson da Silva Araujo, Antonio Fabron Junior, Monica Pinheiro de Almeida Verissimo, Giorgio Roberto Baldanzi, Breno Pannia Esposito, Fernando Tricta, Merula Emmanoel Anargyrou Steagall, Claudia Ângela Galleni Di Sessa Vellozo, Kleber Yotsumoto Fertrin, Ronaldo Hueb Baroni, Nelson Hamerschlak

Subjects: “…Iron overload…”
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The Impact of the Epigenetic Cancer Drug Azacitidine on Host Immunity: The Role of Myelosuppression, Iron Overload and <i>tp53</i> Mutations in a Zebrafish Model by Shu-Ching Wang, Ching-Tse Wu, Dong-Yu Wu, Caleb Gon-Shen Chen, Kuo-Ming Chang, Chien-Chung Chang

“…Together, we propose that myelosuppression, iron overload and <i>TP53</i> mutations may represent the host variables that compromise the azacitidine efficacy.…”
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THE USE OF NEXT-GENERATION SEQUENCING TO SCREEN FOR MUTATIONS IN 16 GENES INVOLVED IN IRON HOMEOSTASIS AS AN AID TO GENETIC DIAGNOSIS FOR PATIENTS WITH IRON OVERLOAD OR IRON DEFICIENCY by Bignell, P, Burns, A, Schuh, A, Robson, K

Two trade names of deferasirox (Osveral® and Exjade®) in reduction of iron overload parameters in major beta-thalassemia patients: A randomized open labeled clinical trial by Mohammadreza Rafati, Hossein Karami, Bita Lashtoo-Aghaee, Bahareh Lashtoo-Aghaee, Mojdeh Dabirian, Razieh Avan

“…Background: Beta-thalassemia major patients typically require chronic transfusion and iron-chelating agents to reduce serum iron overload. Osveral® is an available Iranian brand name of deferasirox used by majority of thalassemic patients. …”
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Biochanin A protects against iron overload associated knee osteoarthritis via regulating iron levels and NRF2/System xc-/GPX4 axis by Qi He, Junzheng Yang, Zhaofeng Pan, Gangyu Zhang, Baihao Chen, Shaocong Li, Jiacong Xiao, Fengjin Tan, Zihao Wang, Peng Chen, Haibin Wang

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Amelioration effects of the soybean lecithin–gallic acid complex on iron-overload-induced oxidative stress and liver damage in C57BL/6J mice by Caihong Wu, Wenxin Zhang, Feifei Yan, Wenwen Dai, Fang Fang, Yanli Gao, Weiwei Cui

“…In vivo, C57BL/6J mice were randomized into 4 groups: control, iron-overloaded, iron-overloaded + deferoxamine, and iron-overloaded + SL-GAC. …”
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