Showing 361 - 380 results of 1,083 for search '"Iron overload"', query time: 0.12s Refine Results
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    Efficacy and safety of deferoxamine, deferasirox and deferiprone triple iron chelator combination therapy for transfusion-dependent β-thalassaemia with very high iron overload: a protocol for randomised controlled clinical trial by Anuja Premawardhena, Sachith Mettananda, Chamodi Perera, Muditha Nayana Wijethilaka, Sakuni Keshani Wanasinghe, R H M G Rajakaruna, R A N K K Samarasinghe, Senani Williams

    Published 2024-02-01
    “…Introduction Despite the improvement in medical management, many patients with transfusion-dependent β-thalassaemia die prematurely due to transfusion-related iron overload. As per the current guidelines, the optimal chelation of iron cannot be achieved in many patients, even with two iron chelators at their maximum therapeutic doses. …”
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    Clinical outcome and humoral immune responses of β-thalassemia major patients with severe iron overload to SARS-CoV-2 infection and vaccination: a prospective cohort studyResearch in context by Hussam Ghoti, Hala Zreid, Israa Ghoti, Arno R. Bourgonje, Arjan Diepstra, Harry van Goor, Irit Avivi, Hisham Jeadi, Larissa E. van Eijk, Günter Weiss

    Published 2023-08-01
    “…Summary: Background: COVID-19 has raised special concern for patients with β-thalassemia major (β-TM) due to frequent comorbidities, regular blood transfusions, and iron overload. However, the exact implications of COVID-19 for patients with β-TM remain uncertain. …”
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