Baroreflex function in conscious rats submitted to iron overload by L.M. Cardoso, M.L. Pedrosa, M.E. Silva, M.F.D. Moraes, E. Colombari, D.A. Chianca-Jr.

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MRI assessment of correlation between cardiac biventricular function, myocardial iron overload and pancreatic iron overload in a large cohort of thalassemia major patients by Luciani Antongiulio, Valeri Gianluca, Capra Marcello, Maggio Aurelio, Pignatti Caterina, Missere Massimiliano, Positano Vincenzo, Meloni Antonella, Restaino Gennaro, Sallustio Giuseppina, Pepe Alessia

P1499: GENETIC FACTORS OF IRON OVERLOAD IN HEREDITARY SPHEROCYTOSIS by Lucie Donaty, Muriel Giansily Blaizot, Severine Cunat, Vincent Azoury, Corinne Favier, Vanessa Debant, Fabienne Danton, Robert Navarro, Perrine Mahé, Patricia Aguilar Martinez

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Myocardial iron overload in sickle/thalassemia patients of Italian origin by Meloni Antonella, Ruffo Giovan, Keilberg Petra, D'Ascola Domenico, Quota Alessandra, Ascioti Claudio, Positano Vincenzo, Salvatori Cristina, Gulino Letizia, Lombardi Massimo, Pepe Alessia

Iron Overload, Oxidative Stress, and Ferroptosis in the Failing Heart and Liver by Daniele Mancardi, Mariarosa Mezzanotte, Elisa Arrigo, Alice Barinotti, Antonella Roetto

“…Another paradigmatic organ for transfusion-associated complication due to iron overload is the liver, in which the role of ferroptosis is yet to be elucidated. …”
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Sudden Onset Iron Overload Cardiomyopathy After Liver Transplantation by Alma Habib MD, Adnan Shaaban MD, Julie Thompson MD, Srinath Chinnakotla MD, Cindy M. Martin MD, Gregory M. Vercellotti MD

“…Iron overload cardiomyopathy has been described in patients who develop acute heart failure after liver transplantation but few reports of this are available. …”
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The Role of Iron Overload in Diabetic Cognitive Impairment: A Review by An JR, Wang QF, Sun GY, Su JN, Liu JT, Zhang C, Wang L, Teng D, Yang YF, Shi Y

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Hepatic Failure in COVID-19: Is Iron Overload the Dangerous Trigger? by Franca Del Nonno, Roberta Nardacci, Daniele Colombo, Ubaldo Visco-Comandini, Stefania Cicalini, Andrea Antinori, Luisa Marchioni, Gianpiero D’Offizi, Mauro Piacentini, Laura Falasca

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Metabolic Signature of Dietary Iron Overload in a Mouse Model by Chiara Volani, Giuseppe Paglia, Sigurdur V. Smarason, Peter P. Pramstaller, Egon Demetz, Christa Pfeifhofer-Obermair, Guenter Weiss

“…Here we aimed to characterize the metabolic signature triggered by dietary iron overload over time in a mouse model, where mice received either a standard or a high-iron diet. …”
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P-19 SPLENIC IRON OVERLOAD IN PATIENTS WITH HEREDITARY HEMOCHROMATOSIS by Maria Florencia Yamasato, Mariano Volpacchio, María Alejandra Avagnina, Enzo Rey, Alejandra Vellicce, Esteban Gonzalez Ballerga, Juan Antonio Sordá, Jorge Daruich

“…Introduction and Objectives: Hereditary hemochromatosis (HH) is a polygenic disease characterized by elevated transferrin saturation (TfS) due to progressive and systemic iron overload. T2*-weighted magnetic resonance imaging (T2*MRI) is useful for assessing hepatic and splenic iron overload (SpIO). …”
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A Review on Iron Chelators in Treatment of Iron Overload Syndromes by Naser Mobarra, Mehrnoosh Shanaki, Hassan Ehteram, Hajar Nasiri, Mehdi Sahmani, Mohsen Saeidi, Mehdi Goudarzi, Hoda Pourkarim, Mehdi Azad

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Genetic Iron Overload Hampers Development of Cutaneous Leishmaniasis in Mice by Edouard Charlebois, Yupeng Li, Victoria Wagner, Kostas Pantopoulos, Martin Olivier

“…This allows unrestricted iron entry into the plasma from ferroportin-expressing intestinal epithelial cells and tissue macrophages, resulting in systemic iron overload. Mice were injected with <i>Leishmania major</i> in hind footpads or intraperitoneally. …”
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Diagnosis of iron overload and heart disease by magnetic resonance imaging by J.C. Wood, L. Noetzli

Subjects: “…iron overload, magnetic resonance imaging.…”
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The Impacts of Iron Overload and Ferroptosis on Intestinal Mucosal Homeostasis and Inflammation by Caiyun Huo, Guiping Li, Yanxin Hu, Huiling Sun

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Iron-Overload Conditions: Manifestations to the Kidney Organs – A Review by Nadia Larasinta Heriatmo, Ari Estuningtyas, Vivian Soetikno

“… Excess iron is a risk factor for organ dysfunction and damage resulting in various organ diseases such as liver, heart, and kidney, diabetes mellitus, and neurodegenerative diseases. Iron overload in some individuals is caused by various factors, including genetic predisposition such as genetic hemochromatosis, repeated transfusion of red blood cells, and parenteral iron administration in conditions of transfusion-dependent anemia. …”
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Cardiac iron overload in transfusion-dependent patients with myelodysplastic syndromes. by Roy, N, Myerson, S, Schuh, A, Bignell, P, Patel, R, Wainscoat, J, McGowan, S, Marchi, E, Atoyebi, W, Littlewood, T, Chacko, J, Vyas, P, Killick, S

“…Transfusion-dependent myelodysplastic (MDS) patients are prone to iron overload. We evaluated 43 transfused MDS patients with T2* magnetic resonance imaging scans. 81% had liver and 16·8% cardiac iron overload. …”

COMPREHENSIVE GENETIC TESTING IS REQUIRED FOR PATIENTS WITH UNEXPLAINED IRON OVERLOAD by Bignell, P, Merryweather-Clarke, A, Lok, C, Schuh, A, Robson, K

Porphyria cutanea tarda and beta-thalassaemia minor with iron overload. by Chapman, R

The Impact of Iron Overload and Ferroptosis on Reproductive Disorders in Humans: Implications for Preeclampsia by Shu-Wing Ng, Sam G. Norwitz, Errol R. Norwitz

“…Here, we focus on reproductive disorders associated with iron overload and the contribution of ferroptosis&#8212;programmed cell death mediated by iron-dependent lipid peroxidation within cell membranes&#8212;using preeclampsia as a model system. …”
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Glutathione S transferase polymorphisms influence on iron overload in β-thalassemia patients by Serena Sclafani, Giuseppina Calvaruso, Veronica Agrigento, Aurelio Maggio, Valeria Lo Nigro, Elena D’Alcamo

Subjects: “…glutathione S transferases, β-thalassemia, iron overload.…”
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