Showing 41 - 60 results of 1,083 for search '"Iron overload"', query time: 0.11s Refine Results
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    Oxidative stress induces mitochondrial iron overload and ferroptotic cell death by Yi Chen, Xiaoyun Guo, Yachang Zeng, Xiaoliang Mo, Siqi Hong, Hui He, Jing Li, Sulail Fatima, Qinghang Liu

    Published 2023-09-01
    “…Strikingly, oxidative stress also promoted HO-1 translocation to mitochondria, leading to mitochondrial iron overload and lipid reactive oxygen species (ROS) accumulation. …”
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    Article
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    Molecular responses of iron regulatory proteins to iron overload in human liver by Neonaki, Maria

    Published 2006
    “…It is not iron per se but rather its implication in the generation of reactive oxygen species that makes the metal harmful when present in excess as seen in iron overload disorders, such as in hereditary haemochromatosis (HH). …”
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    Thesis
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    Liver iron overload within a UK based population by sex by Mckay, A, Wilman, H, Kelly, M, Kin, S, Phillips, M, Jandor, A, Bell, J, Thomas, L, Milanesi, M, Neubauer, S, Banerjee, R

    Published 2017
    “…Estimates of iron-overload, the most common cause of which is haemochromatosis, have been lacking within the UK population. …”
    Conference item
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    Iron overload phenotypes and HFE genotypes in white hemochromatosis and iron overload screening study participants without HFE p.C282Y/p.C282Y. by James C Barton, J Clayborn Barton, Ronald T Acton

    Published 2022-01-01
    “…<h4>Background</h4>Screening program participants with iron overload (IO) phenotypes without HFE p.C282Y/p.C282Y are incompletely characterized.…”
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    Article
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    Hyperferritinemia without iron overload in patients with bilateral cataracts: a case series by Mumford Andrew, Bachli Esther B, Kröger Arne, Gubler Christoph

    Published 2011-09-01
    “…</p> <p>Conclusion</p> <p>Hereditary hyperferritinemia cataract syndrome should be considered in all patients with unexplained hyperferritinemia without signs of iron overload, particularly those with juvenile bilateral cataracts. …”
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    Article
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    T lymphocytes and iron overload: novel correlations of possible significance to the biology of the immunological system by Maria de Sousa

    Published 1992-01-01
    “…The recent finding of a correlation between low CD8+ lymphocite numbers, liver demage associated with HCVpositivity and severity of iron overload in B-thalassemia major patients (umpublished data of RW Grandy; P. …”
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    Article
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    Pulmonary function in patients with transfusion-dependent thalassemia and its associations with iron overload by Kate C. Chan, Chun T. Au, Alex W. K. Leung, Albert M. Li, Chi-kong Li, Matthew M. T. Wong, Carol S. T. Li, Hang L. Cheung, Philip Fan, Siu C. Ling, Rever C. H. Li, S. Y. Ha

    Published 2023-03-01
    “…Moreover, it remains unclear whether pulmonary dysfunction is associated with iron overload. This study aimed to evaluate the pulmonary function in patients with TDT and to investigate the associations between pulmonary dysfunction and iron overload. …”
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    Article
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    Exercise and Doxorubicin Modify Markers of Iron Overload and Cardiolipin Deficiency in Cardiac Mitochondria by Ryan N. Montalvo, Franccesco P. Boeno, Imtiaz M. Dowllah, Cesar E. Jacintho Moritz, Branden L. Nguyen, Vivian Doerr, Matthew P. Bomkamp, Ashley J. Smuder

    Published 2023-04-01
    “…The cardiac mitochondria are implicated as the primary target of DOX, resulting in inactivation of electron transport system complexes, oxidative stress, and iron overload. However, it is established that the cardiac mitochondrial subpopulations reveal differential responses to DOX exposure, with subsarcolemmal (SS) mitochondria demonstrating redox imbalance and the intermyofibrillar (IMF) mitochondria showing reduced respiration. …”
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    Article
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    Management of iron overload in the Canadian hematology/oncology population: Implications for nursing practice by Cindy Murray, Tammy De Gelder, Nancy Pringle, J. Colleen Johnston, Mary Doherty

    Published 2016-02-01
    “…However, repeated transfusions over time can lead to iron overload, which, if left untreated, can increase the risk of further malignancy and end-organ damage. …”
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    Article
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