Sponging Away Cardiac Injury by Gizem Kayki-Mutlu, PhD, Kimberly M. Ferrero, MS, Walter J. Koch, PhD

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The Law of Holes by Douglas L. Mann, MD

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Inefficient Batteries in Heart Failure by Brian Schwartz, MPH, MD, Petro Gjini, MD, Deepa M. Gopal, MS, MD, Jessica L. Fetterman, PhD

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An Oral Selective Alpha-1A Adrenergic Receptor Agonist Prevents Doxorubicin Cardiotoxicity by Ju Youn Beak, PhD, Wei Huang, Joel S. Parker, PhD, Sean T. Hicks, BS, Cam Patterson, MD, Paul C. Simpson, MD, Anqi Ma, PhD, Jian Jin, PhD, Brian C. Jensen, MD

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Cardiosphere-Derived Cells Reverse Heart Failure With Preserved Ejection Fraction in Rats by Decreasing Fibrosis and Inflammation by Romain Gallet, MD, Geoffrey de Couto, PhD, Eli Simsolo, BS, Jackelyn Valle, BS, Baiming Sun, MD, Weixin Liu, MS, Eleni Tseliou, MD, Michael R. Zile, MD, Eduardo Marbán, MD, PhD

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Intracoronary Poloxamer 188 Prevents Reperfusion Injury in a Porcine Model of ST-Segment Elevation Myocardial Infarction by Jason A. Bartos, MD, PhD, Timothy R. Matsuura, BA, Adamantios Tsangaris, MD, Matthew Olson, MD, Scott H. McKnite, BS, Jennifer N. Rees, PhD, Karen Haman, PhD, Kadambari Chandra Shekar, MS, Matthias L. Riess, MD, PhD, Frank S. Bates, ScD, Joseph M. Metzger, PhD, Demetris Yannopoulos, MD

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Can President Trump’s (Second) Choice for the Secretary of the Department of Human Health and Services Make Translational Research Great Again? by Douglas L. Mann, MD

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Therapeutic CCR2 Blockade Prevents Inflammation and Alleviates Myxomatous Valve Disease in Marfan Syndrome by Na Xu, PhD, Katherine E. Yutzey, PhD

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Troponin Release Following Brief Myocardial Ischemia by Dulguun Amgalan, MS, Ryan Pekson, PhD, Richard N. Kitsis, MD

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The Programmed Death-1 Signaling Axis Modulates Inflammation and LV Structure/Function in a Stress-Induced Cardiomyopathy Model by Tomohiro Hayashi, MD, PhD, Sajal K. Tiwary, MD, Kory J. Lavine, MD, PhD, Sandeep Acharya, Michael Brent, PhD, Luigi Adamo, MD, PhD, Attila Kovacs, MD, Douglas L. Mann, MD

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Phase II Trials in Drug Development and Adaptive Trial Design by Gail A. Van Norman, MD

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Better Blood Flow Delivered by Ralf A. Benndorf, MD

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A Novel LncRNA SNHG3 Promotes Osteoblast Differentiation Through BMP2 Upregulation in Aortic Valve Calcification by Long Chen, MD, Hanning Liu, MD, PhD, Cheng Sun, MD, PhD, Jianqiu Pei, PhD, Jun Li, MD, Yue Li, PhD, Ke Wei, MD, PhD, Xiaoyi Wang, MD, Peng Wang, MD, Fangzhou Li, MD, Shujie Gai, MD, PhD, Yan Zhao, MD, Zhe Zheng, MD, PhD

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Natriuretic Peptide Receptor-C Protects Against Angiotensin II-Mediated Sinoatrial Node Disease in Mice by Martin Mackasey, BSc, Emmanuel E. Egom, MD, PhD, Hailey J. Jansen, PhD, Rui Hua, PhD, Motahareh Moghtadaei, PhD, Yingjie Liu, PhD, Jaspreet Kaur, PhD, Megan D. McRae, BHSc, Oleg Bogachev, MD, Sara A. Rafferty, MSc, Gibanananda Ray, PhD, Adam W. Kirkby, MSc, Robert A. Rose, PhD

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The Role of Necroptosis in Atherosclerotic Disease by Nicholas J. Leeper, MD

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Cardiac Myosin Binding Protein-C Phosphorylation Mitigates Age-Related Cardiac Dysfunction by Paola C. Rosas, MD, PhD, BSPharm, Chad M. Warren, MS, Heidi A. Creed, BS, Jerome P. Trzeciakowski, PhD, R. John Solaro, PhD, Carl W. Tong, MD, PhD

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Pulsed Cavitational Ultrasound Softening by Olivier Villemain, MD, Justine Robin, MS, Alain Bel, MD, Wojciech Kwiecinski, PhD, Patrick Bruneval, MD, Bastien Arnal, PhD, Mathieu Rémond, PhD, Mickael Tanter, PhD, Emmanuel Messas, MD, PhD, Mathieu Pernot, PhD

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Novel GSK-3β Inhibitor Neopetroside A Protects Against Murine Myocardial Ischemia/Reperfusion Injury by Hyoung Kyu Kim, PhD, Min Kim, PhD, Jubert C. Marquez, PhD, Seung Hun Jeong, PhD, Tae Hee Ko, PhD, Yeon Hee Noh, MS, Pham Trong Kha, PhD, Ha Min Choi, BS, Dong Hyun Kim, PhD, Jong Tae Kim, PhD, Young Il Yang, PhD, Kyung Soo Ko, PhD, Byoung Doo Rhee, PhD, Larisa K. Shubina, PhD, Tatyana N. Makarieva, PhD, Dmitry Y. Yashunsky, PhD, Alexey G. Gerbst, PhD, Nikolay E. Nifantiev, PhD, Valentin A. Stonik, PhD, Jin Han, PhD

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Hydrogen Sulfide Attenuates Renin Angiotensin and Aldosterone Pathological Signaling to Preserve Kidney Function and Improve Exercise Tolerance in Heart Failure by Zhen Li, BS, Chelsea L. Organ, PhD, Jianming Kang, PhD, David J. Polhemus, PhD, Rishi K. Trivedi, PhD, Thomas E. Sharp, III, PhD, Jack S. Jenkins, Ya-xiong Tao, PhD, Ming Xian, PhD, David J. Lefer, PhD

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Emerging Therapeutics for the Treatment of Light Chain and Transthyretin Amyloidosis by Kathleen W. Zhang, MD, Keith E. Stockerl-Goldstein, MD, Daniel J. Lenihan, MD

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