Bimodal Tumor-Targeting from Microenvironment Responsive Hyaluronan Layer-by-Layer (LbL) Nanoparticles by Morton, Stephen Winford, Choi, Jae-Hyeok, Deng, Zhou J., Cho, Nam-Joon, Shopsowitz, Kevin, Hammond, Paula T, Dreaden, Erik

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A Reversible Gene-Targeting Strategy Identifies Synthetic Lethal Interactions between MK2 and p53 in the DNA Damage Response In Vivo by Reinhardt, H. Christian, Kim, Jacob S., Ruf, Daniela M., Mitra, Tanya, Couvillon, Anthony D., Yaffe, Michael B., Cannell, Ian Gordon, Reinhardt, H. Christian, Kim, Jacob S., Ruf, Daniela M., Morandell, Sandra M., Jacks, Tyler E, Yaffe, Michael B

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Impact of Invasive Escherichia Coli Disease on Clinical Outcomes and Medical Resource Utilization Among Asian Patients in the United States by Chao Zhuo, Bo Zheng, Kittima Wattanakamolkul, Yoshikazu Nakayama, Martin Cloutier, Marjolaine Gauthier-Loiselle, Jun Feng, David Wu, Maureen P. Neary, Jeroen Geurtsen, Antoine C. El Khoury, Yoshiaki Gu

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Community engagement in tuberculosis research: the EU-Patient-cEntric clinicAl tRial pLatforms (EU-PEARL) experience by Francesca Saluzzo, Juan Espinosa-Pereiro, Stephan Dressler, Ezio Tàvora Dos Santos Filho, Stephanie Seidel, Jesus Gonzalez Moreno, Norbert Heinrich, Adrian Sanchez-Montalva, Daniela Maria Cirillo

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Termination Based on Event Accrual in Per Protocol Versus Intention to Treat in the ROCKET AF Trial by Anthony P. Carnicelli, Anne S. Hellkamp, Kenneth W. Mahaffey, Daniel E. Singer, Günter Breithardt, Jonathan L. Halperin, Graeme J. Hankey, Jonathan P. Piccini, Richard C. Becker, Christopher C. Nessel, Scott D. Berkowitz, Keith A. A. Fox, Robert M. Califf, Manesh R. Patel

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Immunomodulatory response to neoadjuvant nivolumab in non-metastatic clear cell renal cell carcinoma by Nirmish Singla, Thomas R. Nirschl, Aleksandar Z. Obradovic, Eugene Shenderov, Kara Lombardo, Xiaopu Liu, Alice Pons, Jelani C. Zarif, Steven P. Rowe, Bruce J. Trock, Hans J. Hammers, Trinity J. Bivalacqua, Phillip M. Pierorazio, Julie S. Deutsch, Tamara L. Lotan, Janis M. Taube, Yasser M. A. Ged, Michael A. Gorin, Mohamad E. Allaf, Charles G. Drake

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Treatment-Resistant Depression in America Latina study: one-year follow-up of treatment resistant depression patients under standard of care reveals insights on quality of life, di... by Kelen Recco, Gerardo Garcia Bonetto, Christian Lupo, Antonio E. Nardi, Arnulfo Morales, Claudia Becerra-Palars, Sergio Perocco, Alanna Pfau

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Tumor cells are dislodged into the pulmonary vein during lobectomy by Yao, Xiaosai, Williamson, Christina, D'Agostino, Richard S., Fitton, Torin, Smaroff, Gregory G., Wittrup, Karl Dane, Williams, Robert T., Love, John C, Adalsteinsson, Viktor A.

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qFibrosis: A fully-quantitative innovative method incorporating histological features to facilitate accurate fibrosis scoring in animal model and chronic hepatitis B patients by Xu, Shuoyu, Wang, Yan, Tai, Dean C.S., Wang, Shi, Cheng, Chee Leong, Peng, Qiwen, Yan, Jie, Chen, Yongpeng, Sun, Jian, Liang, Xieer, Zhu, Youfu, Welsch, Roy E., Wee, Aileen, Hou, Jinlin, Yu, Hanry, Rajapakse, Jagath, So, Peter T. C.

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Single cells from human primary colorectal tumors exhibit polyfunctional heterogeneity in secretions of ELR+ CXC chemokines by Adalsteinsson, Viktor A., Tahirova, Narmin, Tallapragada, Naren, Yao, Xiaosai, Campion, Liam, Angelini, Alessandro, Douce, Thomas B., Bowman, Brittany, Williamson, Christina A., Huang, Cindy Y., Kwon, Douglas, Wittrup, Karl Dane, Love, John C

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Five-year Maintenance of Clinical Response and Consistent Safety Profile for Guselkumab in Asian patients with Psoriasis from VOYAGE 1 and VOYAGE 2 by Byung Soo Kim, Seong Jin Jo, SangWoong Youn, Kristian Reich, Carine Saadoun, Chia-Ling Chang, Ya-Wen Yang, Yu-Huei Huang, Tsen-Fang Tsai

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Factors associated with COVID-19-related mental health among Asian Indians in the United States by Mohammad Ikram, Nazneen Fatima Shaikh, Zasim Azhar Siddiqui, Nilanjana Dwibedi, Ranjita Misra, Jamboor K Vishwanatha, Usha Sambamoorthi

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Inhaled mosliciguat (BAY 1237592): targeting pulmonary vasculature via activating apo-sGC by Eva M. Becker-Pelster, Michael G. Hahn, Martina Delbeck, Lisa Dietz, Jörg Hüser, Johannes Kopf, Thomas Kraemer, Tobias Marquardt, Thomas Mondritzki, Johannes Nagelschmitz, Sylvia M. Nikkho, Philippe V. Pires, Hanna Tinel, Gerrit Weimann, Frank Wunder, Peter Sandner, Joachim Schuhmacher, Johannes-Peter Stasch, Hubert K. F. Truebel

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The effect of guselkumab on inhibiting radiographic progression in patients with active psoriatic arthritis: study protocol for APEX, a Phase 3b, multicenter, randomized, double-bl... by Christopher T. Ritchlin, Laura C. Coates, Philip J. Mease, Désirée van der Heijde, Jiao Song, Yusang Jiang, May Shawi, Alexa P. Kollmeier, Proton Rahman

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Increasing glutathione levels by a novel posttranslational mechanism inhibits neuronal hyperexcitability by Ashwini Sri Hari, Rajeswari Banerji, Li-Ping Liang, Ruth E. Fulton, Christopher Quoc Huynh, Timothy Fabisiak, Pallavi Bhuyan McElroy, James R. Roede, Manisha Patel

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Transforming the Information System for Research in Primary Care (SIDIAP) in Catalonia to the OMOP Common Data Model and Its Use for COVID-19 Research by Raventós B, Fernández-Bertolín S, Aragón M, Voss EA, Blacketer C, Méndez-Boo L, Recalde M, Roel E, Pistillo A, Reyes C, van Sandijk S, Halvorsen L, Rijnbeek PR, Burn E, Duarte-Salles T

“…Berta Raventós,1,2,* Sergio Fernández-Bertolín,1,* María Aragón,1 Erica A Voss,3– 5 Clair Blacketer,3– 5 Leonardo Méndez-Boo,6 Martina Recalde,1 Elena Roel,1,2 Andrea Pistillo,1,7 Carlen Reyes,1 Sebastiaan van Sandijk,8 Lars Halvorsen,9 Peter R Rijnbeek,4,5 Edward Burn,1,10 Talita Duarte-Salles1,4 1Fundació Institut Universitari per a la recerca a l’Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), Barcelona, Spain; 2Universitat Autònoma de Barcelona, Bellaterra (Cerdanyola del Vallès), Barcelona, Spain; 3Janssen Pharmaceutical Research and Development, Titusville, NJ, USA; 4Department of Medical Informatics, Erasmus University Medical Center, Rotterdam, the Netherlands; 5OHDSI Collaborators, Observational Health Data Sciences and Informatics (OHDSI), New York, NY, USA; 6Sistemes d’Informació dels Serveis d’Atenció Primària (SISAP), Institut Català de la Salut, Barcelona, Spain; 7Universitat Pompeu Fabra, Barcelona, Spain; 8Odysseus Data Services s.r.o., Prague, Czech Republic; 9edenceHealth NV, Kontich, Belgium; 10Centre for Statistics in Medicine, University of Oxford, Oxford, UK*These authors contributed equally to this workCorrespondence: Talita Duarte-Salles, Fundació Institut Universitari per a la recerca a l’Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), Gran Via Corts Catalanes, 587 àtic, Barcelona, 08007, Spain, Tel +34935824342, Email tduarte@idiapjgol.orgPurpose: The primary aim of this work was to convert the Information System for Research in Primary Care (SIDIAP) from Catalonia, Spain, to the Observational Medical Outcomes Partnership (OMOP) Common Data Model (CDM). …”
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Guselkumab, a Selective Interleukin‐23 p19 Subunit Inhibitor, Resolves Dactylitis in Patients With Active Psoriatic Arthritis: Pooled Results Through Week 52 From Two Phase 3 Studi... by Dennis McGonagle, Iain B. McInnes, Atul Deodhar, Georg Schett, May Shawi, Soumya D. Chakravarty, Alexa P. Kollmeier, Xie L. Xu, Shihong Sheng, Stephen Xu, Christopher T. Ritchlin, Proton Rahman, Phillip J. Mease

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Multiple myeloma: response to treatment and survival of patients according to the interim analysis of the Russian observational, retrospective-prospective, multicenter cohort study... by Vadim V. Ptushkin, Michail A. Kunst, Tatiana A. Mitina, Tatiana S. Konstantinova, Natalia N. Rachkova, Tatiana V. Shelekhova, Ilya V. Elykomov, Galina B. Kuchma, Kiriena O. Farizova, Olga Yu. Vinogradova, Eugene A. Nikitin, Evgeny D. Pashanov

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Healthcare Providers’ knowledge, attitudes and practice in relation to drug hypersensitivity reactions at King Abdulaziz Medical City in Riyadh by Mohammed Alrashed, Ahmed A. Alanazi, Khalid Bin Saleh, Faisal Alanazi, Ahmed S. Alanazi, Sumayyah Mashraqi, Madhawi Mahdali, Abdullah Alshammari, Mohammed A Alnuhait, Mohammed Alzahrani, Tariq Alqahtani

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Low rates of radiographic progression associated with clinical efficacy following up to 2 years of treatment with guselkumab: results from a phase 3, randomised, double-blind, plac... by Philip J Mease, Shihong Sheng, Iain B McInnes, Alice B Gottlieb, Proton Rahman, Soumya D Chakravarty, Alexa P Kollmeier, Xie L Xu, Yusang Jiang, May Shawi, Frédéric Lavie

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