Durability of Protection Post–Primary COVID-19 Vaccination in the United States by Amanda Zheutlin, Miles Ott, Ran Sun, Natalia Zemlianskaia, Craig S. Meyer, Meagan Rubel, Jennifer Hayden, Breno Neri, Tripthi Kamath, Najat Khan, Sebastian Schneeweiss, Khaled Sarsour

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Experience of Autologous Stem Cell Transplant in Multiple Myeloma: The Patient and Caregiver Perspective by Doris K Hansen MD, Todd Bixby MBA, RPh, Karen Fixler, Lisa Shea MPH RD, Christine Brittle PhD, Kimberly Brunisholz PhD, MST, Yi-Hsuan Liu PhD, MS, RD, Jinhai Stephen Huo PhD, MD, MsPH

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Trends in US emergency department visits and subsequent hospital admission among patients with inflammatory bowel disease presenting with abdominal pain: a real-world study from a... by Zhijie Ding, Aarti Patel, James Izanec, Christopher D. Pericone, Jennifer H. Lin, Christopher W. Baugh

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Targeted CQA analytical control strategy for commercial antibody products: Replacing ion-exchange chromatography methods for charge heterogeneity with multi-attribute monitoring by Adam R. Evans, Joseph Mulholland, Michael J. Lewis, Ping Hu

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PB2679: MIXED-METHOD, CROSS-SECTIONAL SURVEY TO DESCRIBE FEELINGS, PERCEPTION, AND EXPERIENCE OF MULTIPLE MYELOMA PATIENTS WHO SWITCHED FROM INTRAVENOUS DARATUMUMAB TO THE SUBCUTAN... by Valeria Magarotto, Julien Thevenon, Kate Morgan, Silene Ten Seldam, Wafae Iraqi, Xavier Guillaume, Dahbia Horchi, Bleuenn Rault, Traugott Ludwig Gruppe

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The Burden of a Multiple Myeloma Diagnosis on Patients and Caregivers in the First Year: Western European Findings by Gatopoulou X, Iraqi W, Morgan K, Helme K, Spain VA, Redfearn J, Gardiner B

“…Xenia Gatopoulou,1 Wafae Iraqi,2 Kate Morgan,3 Kawitha Helme,4 Victoria A Spain,5 Jennifer Redfearn,5 Brett Gardiner5 1Health Economics, Market Access and Reimbursement EMEA, Janssen Pharmaceuticals, Athens, Greece; 2Patient Engagement, Janssen Pharmaceuticals, Issy-les-Moulineaux, France; 3Myeloma Patients Europe, Brussels, Belgium; 4Health Economics, Market Access and Reimbursement EMEA, Janssen Pharmaceuticals, High Wycombe, UK; 5The Research Partnership, London, UKCorrespondence: Wafae Iraqi, Janssen Pharmaceuticals, 1, Rue Camille Desmoulins, TSA 91003, Issy-les-Moulineaux, 92787, France, Email wiraqi@its.jnj.comBackground: This research aimed to quantify the burden of illness (BoI) in transplant eligible (TE) and transplant non-eligible (TNE) newly diagnosed multiple myeloma (NDMM) patients and their caregivers, in the first year after diagnosis: at months 0, 3, and 12.Methods: Prospective, cross-sectional, observational NDMM study of TE and TNE patients and their caregivers from France, Germany, Italy, and Spain was conducted between May 2019 and January 2021. …”
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Targeted Literature Review of the Burden of Respiratory Syncytial Infection among High-Risk and Elderly Patients in Asia Pacific Region by Daisuke Kurai, JoonYoung Song, Yhu-Chering Huang, Zhijun Jie, Petar Atanasov, Xiaobin Jiang, Luis Hernandez-Pastor, Tom Hsun-Wei Huang, SeongBeom Park, KyungHwa Lim, Peter C. Richmond

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Real-World Epidemiology, Treatment Patterns, and Disease Burden of Chronic Hepatitis B and HDV Co-Infection in South Korea by Yuri Cho, SeongBeom Park, SeonYoung Park, WonJung Choi, Book Kim, Helin Han

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The 56th Bürgenstock Conference by Cyetana Zarate, Jovana V. Milic

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Analytical Challenges and Regulatory Requirements for Nasal Drug Products in Europe and the U.S. by Sabrina Trows, Klaus Wuchner, Rene Spycher, Hartwig Steckel

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Risk Factors for Pulmonary Arterial Hypertension in Patients With Systemic Lupus Erythematosus: A Systematic Review and Expert Consensus by Tatsuya Atsumi, Sang‐Cheol Bae, Hong Gu, Wen‐Nan Huang, Mengtao Li, Mandana Nikpour, Masato Okada, David Prior, Petar Atanasov, Xiaobin Jiang, Liam Wilson, Paul Bloomfield, David Bin‐chia Wu, Yogeshwar Makanji

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The Role of Pharmaceutical Innovation in Clinical Practice Guidelines for Chronic Diseases by Meaghan Roach, Natalie Land, Jennifer Hernandez, Reina Rau, Jacquelyn W. Chou, Stacey S. Hickson, Danielle F. Rollmann, J. Ross Maclean

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Ibrutinib and rituximab plus cyclophosphamide, doxorubicin, vincristine and prednisone in patients with previously untreated non‐germinal centre B‐cell‐like diffuse large B‐cell ly... by Jun Zhu, Xiaonan Hong, Yu Qin Song, Brendan Hodkinson, Sriram Balasubramanian, Songbai Wang, Qingyuan Zhang, Yuankai Shi, Huiqiang Huang, Huilai Zhang, Yan Zhu, Stephen Martin Shreeve, Steven Sun, Ze Wang, Xiaocan Wang, Yue Fan, Wyndham Wilson, Jessica Vermeulen

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Caregiver burden in schizophrenia following paliperidone palmitate long acting injectables treatment: pooled analysis of two double-blind randomized phase three studies by Srihari Gopal, Haiyan Xu, Kelly McQuarrie, Adam Savitz, Isaac Nuamah, Kimberly Woodruff, Maju Mathews

“…Srihari Gopal and colleagues at Janssen Pharmaceuticals have pooled data from two large studies involving 1498 caregivers across 27 countries. …”
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Psychometric Evaluation of the Parent Effort Scale by Katherine B. Bevans, Taye M. Hallock, Aimee Piller, Beth Pfeiffer

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Shared Decision-Making in the Treatment of Multiple Sclerosis: Results of a Cross-Sectional, Real-World Survey in Europe and the United States by Keenan A, Le HH, Gandhi K, Adedokun L, Jones E, Unsworth M, Pike J, Trenholm E

“…Alexander Keenan,1 Hoa H Le,1 Kavita Gandhi,2 Lola Adedokun,3 Eddie Jones,4 Mia Unsworth,4 James Pike,5 Emily Trenholm4 1Scientific Affairs, Janssen Pharmaceuticals Inc., Titusville, NJ, USA; 2Research and Development, Janssen Pharmaceuticals Inc., Titusville, NJ, USA; 3Research and Development, Janssen-Cilag Ltd, High Wycombe, UK; 4Central Nervous System, Adelphi Real World, Bollington, Cheshire, UK; 5Statistics & Data Analytics, Adelphi Real World, Bollington, Cheshire, UKCorrespondence: Mia Unsworth, Adelphi Real World, Adelphi Mill, Grimshaw Lane, Macclesfield, Bollington, Cheshire, SK10 5JB, United Kingdom, Tel +441625578677, Email mia.unsworth@adelphigroup.comIntroduction: Multiple sclerosis (MS) is a neurodegenerative disease characterized by progressive deterioration of cognitive and physical functioning, reducing activities of daily living and quality of life (QoL). …”
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Author Correction: Performance assessment and economic analysis of a human Liver-Chip for predictive toxicology by Lorna Ewart, Athanasia Apostolou, Skyler A. Briggs, Christopher V. Carman, Jake T. Chaff, Anthony R. Heng, Sushma Jadalannagari, Jeshina Janardhanan, Kyung-Jin Jang, Sannidhi R. Joshipura, Mahika M. Kadam, Marianne Kanellias, Ville J. Kujala, Gauri Kulkarni, Christopher Y. Le, Carolina Lucchesi, Dimitris V. Manatakis, Kairav K. Maniar, Meaghan E. Quinn, Joseph S. Ravan, Ann Catherine Rizos, John F. K. Sauld, Josiah D. Sliz, William Tien-Street, Dennis Ramos Trinidad, James Velez, Max Wendell, Onyi Irrechukwu, Prathap Kumar Mahalingaiah, Donald E. Ingber, Jack W. Scannell, Daniel Levner

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Ketamine: stimulating antidepressant treatment? by Malhi, G, Byrow, Y, Cassidy, F, Cipriani, A, Demyttenaere, K, Frye, M, Gitlin, M, Kennedy, S, Ketter, T, Lam, R, McShane, R, Mitchell, A, Ostacher, M, Rizvi, S, Thase, M, Tohen, M

“….; consultant/advisory board bember: Allergan, Inc., Janssen Pharmaceuticals, Myriad Genetic Laboratories, Inc., and Sunovion Pharmaceuticals; lecture honoraria (not Speaker's Bureau payments): GlaxoSmithKline, and Sunovion Pharmaceuticals; royalties from American Psychiatric Publishing, Inc. …”

Climate footprint of industry-sponsored clinical research: an analysis of a phase-1 randomised clinical study and discussion of opportunities to reduce its impact by Michael Collins, Thomas Costelloe, Jason Keith LaRoche, Rodrigo Alvarenga, Wouter De Soete, Jeremy Faludi, Kristel Rens

“…Objective This study aims to calculate the global warming potential, in carbon dioxide (CO2) equivalent emissions, from all in-scope activities involved in a phase-1 clinical study.Design Retrospective analysis.Data source Internal data held by Janssen Pharmaceuticals.Studies included Janssen-sponsored TMC114FD1HTX1002 study conducted between 2019 and 2021.Main outcome Measure CO2 equivalents (CO2e) for in-scope clinical trial activities calculated according to intergovernmental panel on climate change 2021 impact assessment methodology.Results The CO2e emissions generated by the trial were 17.65 tonnes. …”
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The age-specific comorbidity burden of mild cognitive impairment: a US claims database study by Gang Li, Nicola Toschi, Viswanath Devanarayan, Richard Batrla, Tommaso Boccato, Min Cho, Matteo Ferrante, Feride Frech, James E. Galvin, David Henley, Soeren Mattke, Susan De Santi, Harald Hampel

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