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Prospects of genome editing using CRISPR/CAS or how to master genetic scissors. Nobel Prize in Chemistry 2020
Published 2021-02-01Subjects: Get full text
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Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2
Published 2019-06-01Get full text
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CRISPR/Cas9 from bench to bedside: what clinicians need to know before application?
Published 2020-12-01“…Emmanuelle Charpentier and Dr. Jennifer Doudna won the Nobel Prize in Chemistry for their pioneering work in precise genome editing using the CRISPR technology. …”
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Understanding on CRISPR/Cas9 mediated cutting-edge approaches for cancer therapeutics
Published 2022-06-01“…(J Bacteriol 169:5429–5433, 1987) and the journey comprises the recent Nobel Prize award (2020), conferred to Emmanuelle Charpentier and Jennifer Doudna. Cumulatively, the CRISPR has a short, compact, and most discussed success of its application in becoming one of the most versatile and paradigm shifting technologies of Biological Research. …”
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Addressing Conflicts of Interest and Conflicts of Commitment in Public Advocacy and Policy Making on CRISPR/Cas-Based Human Genome Editing
Published 2022-04-01“…Leading experts on CRISPR/Cas-based genome editing—such as 2020 Nobel laureates Jennifer Doudna and Emmanuelle Charpentier—are not only renowned specialists in their fields, but also public advocates for upcoming regulatory frameworks on CRISPR/Cas. …”
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A review on CRISPR-Cas9 and its role in cancer immunotherapy
Published 2021-09-01“…The Nobel Prize in Chemistry was awarded to Emanuelle Charpentier and Jennifer Doudna for their work on CRISPR-Cas9 and its application as a genome engineering tool. …”
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Application of the CRISPR/Cas9-based gene editing technique in basic research, diagnosis, and therapy of cancer
Published 2021-10-01“…Abstract The 2020 Nobel Prize in Chemistry was awarded to Emmanuelle Charpentier and Jennifer Doudna for the development of the Clustered regularly interspaced short palindromic repeats/CRISPR-associated nuclease9 (CRISPR/Cas9) gene editing technology that provided new tools for precise gene editing. …”
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Shifting Perceptions of CRISPR
Published 2021-08-01“…Photo by National Cancer Institute on Unsplash INTRODUCTION More than 20 cell and gene therapies are now available to safely minimize genetic diseases such as retinal dystrophy (LUXTURNA), some B-cell lymphomas (YESCARTA), and B-cell lymphoblastic leukemia (KYMRIAH).[1] One such gene-editing tool is Clustered Regular Inter Spaced Palindromic Repeats (CRISPR) and its associated proteins or CRISPR-Cas. Jennifer Doudna and Emmanuelle Charpentier described CRISPR’s potential as an accurate genome editing tool in 2012. …”
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The Dubious Benefits of Germline Editing
Published 2018-09-01“…In 2012, Berkeley scientist Jennifer Doudna and team demonstrated that CRISPR could be reprogrammed to target and alter ostensibly any gene of any organism on earth [3]. …”
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