Pairwise comparison of hydrochlorothiazide and chlorthalidone responses among hypertensive patients by Lakshmi Manasa S. Chekka, Rhonda M. Cooper‐DeHoff, John G. Gums, Arlene B. Chapman, Julie A. Johnson

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Influence of Genetic West African Ancestry on Metabolomics among Hypertensive Patients by Mai Mehanna, Caitrin W. McDonough, Steven M. Smith, Yan Gong, John G. Gums, Arlene B. Chapman, Julie A. Johnson, Rhonda M. Cooper-DeHoff

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2235 by Meghan J. Arwood, Caitrin Rowe McDonough, Larisa H. Cavallari, Amanda R. Elsey, Reginald F. Frye, Yan Gong, Julie A. Johnson, Kristin W. Weitzel, Taimour Langaee

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Circulating microRNA Biomarkers of Thiazide Response in Hypertension by Lakshmi Manasa S. Chekka, Marwa Tantawy, Taimour Langaee, Danxin Wang, Rolf Renne, Arlene B. Chapman, John G. Gums, Eric Boerwinkle, Rhonda M. Cooper‐DeHoff, Julie A. Johnson

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Metabolomics Signature of Plasma Renin Activity and Linkage with Blood Pressure Response to Beta Blockers and Thiazide Diuretics in Hypertensive European American Patients by Mai Mehanna, Caitrin W. McDonough, Steven M. Smith, Yan Gong, John G. Gums, Arlene B. Chapman, Julie A. Johnson, Lauren McIntyre, Rhonda M. Cooper-DeHoff

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Strategies to Integrate Genomic Medicine into Clinical Care: Evidence from the IGNITE Network by Nina R. Sperber, Olivia M. Dong, Megan C. Roberts, Paul Dexter, Amanda R. Elsey, Geoffrey S. Ginsburg, Carol R. Horowitz, Julie A. Johnson, Kenneth D. Levy, Henry Ong, Josh F. Peterson, Toni I. Pollin, Tejinder Rakhra-Burris, Michelle A. Ramos, Todd Skaar, Lori A. Orlando

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Sphingolipid Metabolic Pathway Impacts Thiazide Diuretics Blood Pressure Response: Insights From Genomics, Metabolomics, and Lipidomics by Mohamed H. Shahin, Yan Gong, Reginald F. Frye, Daniel M. Rotroff, Amber L. Beitelshees, Rebecca A. Baillie, Arlene B. Chapman, John G. Gums, Stephen T. Turner, Eric Boerwinkle, Alison Motsinger‐Reif, Oliver Fiehn, Rhonda M. Cooper‐DeHoff, Xianlin Han, Rima Kaddurah‐Daouk, Julie A. Johnson

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Design and Early Implementation Successes and Challenges of a Pharmacogenetics Consult Clinic by Meghan J. Arwood, Eric A. Dietrich, Benjamin Q. Duong, D. Max Smith, Kelsey Cook, Amanda Elchynski, Eric I. Rosenberg, Katherine N. Huber, Ying L. Nagoshi, Ashleigh Wright, Jeffrey T. Budd, Neal P. Holland, Edlira Maska, Danielle Panna, Amanda R. Elsey, Larisa H. Cavallari, Kristin Wiisanen, Julie A. Johnson, John G. Gums

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A randomized, cross‐over trial of metoprolol succinate formulations to evaluate PK and PD end points for therapeutic equivalence by Scott A. Mosley, Sarah Kim, Nihal El Rouby, Karthik Lingineni, Valvanera Vozmediano Esteban, Yan Gong, Yiqing Chen, David Estores, Kairui Feng, Hyewon Kim, Minori Kinjo, Taimour Langaee, Zhichuan Li, Siegfried O. F. Schmidt, Julie A. Johnson, Reginald F. Frye, Lanyan (Lucy) Fang, Liang Zhao, Philip F. Binkley, Stephan Schmidt, Larisa H. Cavallari

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Genetic Contributors of Efficacy and Adverse Metabolic Effects of Chlorthalidone in African Americans from the Genetics of Hypertension Associated Treatments (GenHAT) Study by Nicole D. Armstrong, Vinodh Srinivasasainagendra, Lakshmi Manasa S. Chekka, Nam H. K. Nguyen, Noor A. Nahid, Alana C. Jones, Rikki M. Tanner, Bertha A. Hidalgo, Nita A. Limdi, Steven A. Claas, Yan Gong, Caitrin W. McDonough, Rhonda M. Cooper-DeHoff, Julie A. Johnson, Hemant K. Tiwari, Donna K. Arnett, Marguerite R. Irvin

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CYP2C19 Genotype‐Guided Antiplatelet Therapy After Percutaneous Coronary Intervention in Diverse Clinical Settings by Amber L. Beitelshees, Cameron D. Thomas, Philip E. Empey, George A. Stouffer, Dominick J. Angiolillo, Francesco Franchi, Sony Tuteja, Nita A. Limdi, James C. Lee, Julio D. Duarte, Rolf P. Kreutz, Todd C. Skaar, James C. Coons, Jay Giri, Caitrin W. McDonough, Rachel Rowland, James M. Stevenson, Thuy Thai, Mark R. Vesely, Jacob T. Wellen, Julie A. Johnson, Almut G. Winterstein, Larisa H. Cavallari, Craig R. Lee

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Associations of Polymorphisms in the Peroxisome Proliferator-Activated Receptor Gamma Coactivator-1 Alpha Gene With Subsequent Coronary Heart Disease: An Individual-Level Meta-Anal... by Tessa Schillemans, Vinicius Tragante, Buamina Maitusong, Bruna Gigante, Bruna Gigante, Sharon Cresci, Federica Laguzzi, Max Vikström, Mark Richards, Mark Richards, Anna Pilbrow, Vicky Cameron, Luisa Foco, Robert N. Doughty, Pekka Kuukasjärvi, Hooman Allayee, Hooman Allayee, Jaana A. Hartiala, W. H. Wilson Tang, W. H. Wilson Tang, Leo-Pekka Lyytikäinen, Leo-Pekka Lyytikäinen, Kjell Nikus, Kjell Nikus, Jari O. Laurikka, Jari O. Laurikka, Sundararajan Srinivasan, Ify R. Mordi, Stella Trompet, Stella Trompet, Adriaan Kraaijeveld, Jessica van Setten, Crystel M. Gijsberts, Crystel M. Gijsberts, Anke H. Maitland-van der Zee, Christoph H. Saely, Christoph H. Saely, Christoph H. Saely, Yan Gong, Julie A. Johnson, Julie A. Johnson, Rhonda M. Cooper-DeHoff, Rhonda M. Cooper-DeHoff, Carl J. Pepine, Gavino Casu, Andreas Leiherer, Andreas Leiherer, Heinz Drexel, Heinz Drexel, Heinz Drexel, Benjamin D. Horne, Benjamin D. Horne, Sander W. van der Laan, Nicola Marziliano, Nicola Marziliano, Stanley L. Hazen, Stanley L. Hazen, Juha Sinisalo, Mika Kähönen, Mika Kähönen, Terho Lehtimäki, Terho Lehtimäki, Chim C. Lang, Ralph Burkhardt, Ralph Burkhardt, Markus Scholz, J. Wouter Jukema, J. Wouter Jukema, Niclas Eriksson, Axel Åkerblom, Axel Åkerblom, Stefan James, Stefan James, Claes Held, Claes Held, Emil Hagström, John A. Spertus, Ale Algra, Ulf de Faire, Agneta Åkesson, Folkert W. Asselbergs, Folkert W. Asselbergs, Riyaz S. Patel, Riyaz S. Patel, Karin Leander

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Implementing a pragmatic clinical trial to tailor opioids for acute pain on behalf of the IGNITE ADOPT PGx investigators by Larisa H. Cavallari, Emily Cicali, Kristin Wiisanen, Roger B. Fillingim, Hrishikesh Chakraborty, Rachel A. Myers, Kathryn V. Blake, Bolanle Asiyanbola, Jordan F. Baye, Wesley H. Bronson, Kelsey J. Cook, Erica N. Elwood, Chancellor F. Gray, Yan Gong, Lindsay Hines, Joseph Kannry, Natalie Kucher, Sheryl Lynch, Khoa A. Nguyen, Aniwaa Owusu Obeng, Victoria M. Pratt, Hernan A. Prieto, Michelle Ramos, Azita Sadeghpour, Rajbir Singh, Marc Rosenman, Petr Starostik, Cameron D. Thomas, Emma Tillman, Paul R. Dexter, Carol R. Horowitz, Lori A. Orlando, Josh F. Peterson, Todd C. Skaar, Sara L. Van Driest, Simona Volpi, Deepak Voora, Hari K. Parvataneni, Julie A. Johnson, for the IGNITE Pragmatic Trials Network

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A Pharmacogenetics-Based Approach to Managing Gastroesophageal Reflux Disease: Current Perspectives and Future Steps by Eken E, Estores DS, Cicali EJ, Wiisanen KK, Johnson JA

“…Eda Eken,1,2 David S Estores,3 Emily J Cicali,1,2 Kristin K Wiisanen,1,2 Julie A Johnson1,2 1Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Gainesville, FL, USA; 2Center for Pharmacogenomics and Precision Medicine, University of Florida, Gainesville, FL, USA; 3Division of Gastroenterology, Hepatology, and Nutrition, College of Medicine, University of Florida, Gainesville, FL, USACorrespondence: Julie A Johnson, University of Florida, Department of Pharmacotherapy and Translational Research, Box 100486, Gainesville, FL, 32610-0486, USA, Tel +1-352-273-6310, Email Julie.johnson@ufl.eduAbstract: Proton pump inhibitors (PPIs) are commonly used medications to treat acid-related conditions, including gastro-esophageal reflux disease (GERD). …”
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