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12681
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12682
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12683
Translocator protein is a marker of activated microglia in rodent models but not human neurodegenerative diseases
Published 2023“…Positron emission tomography (PET) targeting 18 kDa Translocator Protein (TSPO) is widely used for localising inflammation in vivo, but its quantitative interpretation remains uncertain. …”
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Journal Article -
12684
Novel nanocomposite forward osmosis membranes for treating highly saline and oily wastewater with low fouling, high water flux and high selectivity
Published 2016“…The best crosslinking agent is identified as glutaraldehyde; the optimum molecular weight of hydrogel is found to be 93 kDa; the optimum concentration of hydrogel solution is 0.25 wt%; the optimum coating time is 20 min; and more importantly, the optimum crosslinking degree is determined as 30%. …”
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Thesis -
12685
Extraction, Partial Purification and Characterisation of a Protease Extracted from Kesinai (Streblus Asper Lour.) Leaves, and its Potential Application in the Production of Cheddar...
Published 2011“…The partially purified enzyme appeared as a single band on SDS PAGE with an apparent molecular weight of 75.8 kDa. The maximum coagulation activity was observed at pH 6.0 and at temperature 70 oC. …”
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Thesis -
12686
Extraction and characterization of Jatropha curcas L. as natural coagulant and its application for turbidity removal
Published 2014“…The active ingredient of J. curcas -extract coagulant was a protein with molecular weight 30-35 kDa. In a synthetic turbid water using kaolin particles at pH 5, OCE-JcPc coagulant reduced turbidity by at least 90% for a wide range of initial turbidities. …”
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Thesis -
12687
Multi-targeted therapy resistance via drug-induced secretome fucosylation
Published 2023-03-01“…In cancer cell cultures, xenograft mouse models, and patients, targeted kinase inhibitors distinctively induced core fucosylation of secreted proteins less than 60 kDa. Label-free proteomics of N-glycoproteomes identified fucosylation of the antioxidant PON1 as a critical component of the therapy-induced secretome (TIS). …”
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12688
Associations between sex, body mass index and the individual microglial response in Alzheimer’s disease
Published 2024-01-01“…Abstract Background and objectives 18-kDa translocator protein position-emission-tomography (TSPO-PET) imaging emerged for in vivo assessment of neuroinflammation in Alzheimer’s disease (AD) research. …”
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12689
Localization in vivo and in vitro confirms EnApiAP2 protein encoded by ENH_00027130 as a nuclear protein in Eimeria necatrix
Published 2023-12-01“…The native EnApiAP2 protein was detected in sporozoites (SZ) and second generation merozoites (MZ-2) extracts, with a size of approximately 210 kDa. A quantitative real-time PCR (qPCR) analysis showed that the transcription level of EnApiAP2 was significantly higher in SZ than in MZ-2, third generation merozoites (MZ-3) and gametocytes (P<0.01). …”
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Article -
12690
New hybrid radio-fluorescent probes [131I]-BPF-01 and [131I]-BPF-02 for visualisation of cancer cells: Synthesis and preliminary in vitro and ex vivo evaluations
Published 2023-10-01“…The magnetic bead assay suggests that [131I]-BPF-02 and [131I]-BPF-02 showed a promising capability to interact with translocator protein 18 kDa (TSPO). Moreover, the computational data showed that the binding scores for ligands 7–8, BPF-01 and BPF-02, and [131I]-BPF-01 and [131I]-BPF-02 in the TSPO were considerably high. …”
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Article -
12691
1,8-Naphthalimide-Based Multifunctional Compounds as Cu2+ Probes, Lysosome Staining Agents, and Non-viral Vectors
Published 2019-09-01“…Among them, compound 1d modified with long hydrophobic chain exhibited the best RNA delivery efficiency in the four tested cell lines, and the performance was far better than lipofectamine 2000 and 25 kDa PEI, indicating the potential application in non-viral vectors.…”
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Article -
12692
One-year surveillance of SARS-CoV-2 in wastewater from vulnerable urban communities in metropolitan São Paulo, Brazil
Published 2022-02-01“…SARS-CoV-2 infectivity was tested in Vero E6 cells after concentration with the two techniques, ultrafiltration (Centricon® Plus-70 10 kDa) and sucrose cushion ultracentrifugation, but none of the evaluated samples presented positive results. …”
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12693
Murine model identifies tropomyosin as IgE cross-reactive protein between house dust mite and coho salmon that possibly contributes to the development of salmon allergy
Published 2023-08-01“…Serum IgE from Der p or Der f extract-sensitized mice was bound strongly to protein fractions separated by anion exchange chromatography of coho salmon proteins precipitated with 50% ammonium sulfate, which massively contained the approximately 38 kDa protein. We found that serum IgE from Der p extract-sensitized mice was bound to recombinant coho salmon tropomyosin. …”
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12694
Development of an immunoassay for the simultaneous detection of GADA and ZnT8A in autoimmune diabetes using a ZnT8/GAD65 chimeric molecule
Published 2023-08-01“…IntroductionThe combined presence of autoantibodies to the 65 kDa isoform of glutamic acid decarboxylase (GADA) and to the islet-specific cation efflux transporter ZnT8 (ZnT8A) in serum is the best predictive sign of the loss of immune tolerance and the clinical manifestation of autoimmune diabetes mellitus (DM). …”
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12695
Resposta e níveis críticos de potássio para o arroz cultivado em solos de várzea inundados Response and critical levels of potassium for rice cultivated in lowland waterlogged soil...
Published 2004-02-01“…O delineamento experimental utilizado foi o inteiramente casualizado, em esquema fatorial 4x5, com quatro repetições, sendo quatro solos de várzea [Neossolo Flúvico (RU), Gleissolo Háplico (GX), Gleissolo Melânico (GM) e Organossolo Mésico (OY)] e cinco níveis de saturação por K da CTC potencial (natural, 4, 6, 8 e 10%). As saturações naturais foram de 1,49, 1,65, 1,30 e 1,55% para os solos RU, GX, GM e OY, respectivamente. …”
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Article -
12696
Tuna trimmings (Thunnas albacares) hydrolysate alleviates immune stress and intestinal mucosal injury during chemotherapy on mice and identification of potentially active peptides
Published 2023-01-01“…Peptide molecular weight distribution analysis of TPA indicated that peptides ranging from 0.25 to 1 kDa constituted 64.54%. LC-MS/MS analysis identified 109 peptide sequences, which were predicted to possess anti-cancer and anti-inflammatory activities through database prediction. …”
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12697
[18F]F-DED PET imaging of reactive astrogliosis in neurodegenerative diseases: preclinical proof of concept and first-in-human data
Published 2023-03-01“…Methods A cross-sectional cohort of 24 transgenic (PS2APP) and 25 wild-type mice (age range: 4.3–21.0 months) underwent 60 min dynamic [18F]fluorodeprenyl-D2 ([18F]F-DED), static 18 kDa translocator protein (TSPO, [18F]GE-180) and β-amyloid ([18F]florbetaben) PET imaging. …”
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Article -
12698
Luteolin Attenuates Hypertension via Inhibiting NF-κB-Mediated Inflammation and PI3K/Akt Signaling Pathway in the Hypothalamic Paraventricular Nucleus
Published 2023-01-01“…Furthermore, immunofluorescence results showed that injection of luteolin in the PVN reduced the expression of tyrosine hydroxylase (TH), and increased that of superoxide dismutase (SOD1) and the 67-kDa isoform of glutamate decarboxylase (GAD67) in the PVN of SHRs. …”
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12699
Modulatory actions of Echinococcus granulosus antigen B on macrophage inflammatory activation
Published 2024-03-01“…In E. granulosus s.l., one of these lipoproteins is antigen B (EgAgB), codified by a multigenic and polymorphic family that gives rise to five gene products (EgAgB8/1-5 subunits) assembled as a 230 kDa macromolecule. EgAgB has a diagnostic value for cystic echinococcosis, but its putative role in the immunobiology of this infection is still poorly understood. …”
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Article -
12700
The codon-optimized capsid gene of duck circovirus can be highly expressed in yeast and self-assemble into virus-like particles
Published 2017-07-01“…After the induction expression, the secretory type of Cap protein, which was about 43 kDa, was best expressed under 0.5% (v/v) methanol and sorbitol induction. …”
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