Pediatric acute asthma scoring systems: a systematic review and survey of UK practice by Jerry Chacko, Charlotte King, David Harkness, Shrouk Messahel, Julie Grice, John Roe, Niall Mullen, Ian P. Sinha, Daniel B. Hawcutt, PERUKI

“…A survey of Paediatric Emergency Research in the United Kingdom and Ireland (PERUKI) sites was undertaken to ascertain routinely collected asthma data and information about severity scores. …”
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Early cost-effectiveness analysis of screening for preeclampsia in nulliparous women: A modelling approach in European high-income settings. by Neily Zakiyah, Robin Tuytten, Philip N Baker, Louise C Kenny, Maarten J Postma, Antoinette D I van Asselt, IMPROvED Consortium

“…<h4>Objectives</h4>To develop an early cost-effectiveness analysis to assess both costs and health outcomes of a new screening test for preeclampsia from a healthcare payer perspective, in the United Kingdom (UK), Ireland, the Netherlands and Sweden.<h4>Methods</h4>A decision tree over a 9-month time horizon was developed to explore the cost-effectiveness of the new screening test for preeclampsia compared to the current screening strategy. …”
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Early cost-effectiveness analysis of screening for preeclampsia in nulliparous women: A modelling approach in European high-income settings by Neily Zakiyah, Robin Tuytten, Philip N. Baker, Louise C. Kenny, Maarten J. Postma, Antoinette D. I. van Asselt, on behalf of IMPROvED Consortium

“…<h4>Objectives</h4> To develop an early cost-effectiveness analysis to assess both costs and health outcomes of a new screening test for preeclampsia from a healthcare payer perspective, in the United Kingdom (UK), Ireland, the Netherlands and Sweden. <h4>Methods</h4> A decision tree over a 9-month time horizon was developed to explore the cost-effectiveness of the new screening test for preeclampsia compared to the current screening strategy. …”
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“Girls Aren’t Meant to Exercise”: Perceived Influences on Physical Activity among Adolescent Girls—The HERizon Project by Emma S. Cowley, Paula M. Watson, Lawrence Foweather, Sarahjane Belton, Andrew Thompson, Dick Thijssen, Anton J. M. Wagenmakers

“…A total of 48 adolescent girls (13–18 years) from low socioeconomic areas of the United Kingdom and Ireland participated in focus groups (<i>n</i> = 8), to explore perspectives of physical activity and the influence of gender within this. …”
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Rural chronic disease research patterns in the United Kingdom, United States, Canada, Australia and New Zealand: a systematic integrative review by R. Disler, K. Glenister, J. Wright

“…One hundred sixty were included in the review including 68 from the United States, 59 from Australia and New Zealand (5), 21 from Canada and 11 from the United Kingdom and Ireland. 53% (84) focused on cardiovascular disease; 27% (43) diabetes mellitus; 8% (12) chronic obstructive pulmonary disease; and 13% (27) chronic kidney disease. …”
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Principles for the production of evidence‐based guidance for conservation actions by Harriet Downey, Vincent Bretagnolle, Cameron Brick, Caroline R. Bulman, Steven J. Cooke, Mike Dean, Bob Edmonds, Winifred F. Frick, Kim Friedman, Catherine McNicol, Christopher Nichols, Saul Herbert, David O'Brien, Nancy Ockendon, Silviu Petrovan, David Stroud, Thomas B. White, Thomas A. Worthington, William J. Sutherland

“…We reviewed conservation guidance for mitigation and management of species and habitats in the United Kingdom and Ireland, identifying 301 examples produced by over 50 organizations. …”
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The Antidepressant-Like Effects of a Clinically Relevant Dose of Ketamine Are Accompanied by Biphasic Alterations in Working Memory in the Wistar Kyoto Rat Model of Depression by Conor W. McDonnell, Fionn Dunphy-Doherty, Jennifer Rouine, Massimiliano Bianchi, Neil Upton, Ewa Sokolowska, Jack A. Prenderville

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Enhancing the implementation and sustainability of fundamental movement skill interventions in the UK and Ireland: lessons from collective intelligence engagement with stakeholders by Jiani Ma, Michael J. Hogan, Emma L. J. Eyre, Natalie Lander, Lisa M. Barnett, Michael J. Duncan

“…Methods Three CI sessions were conducted with three separate groups of experienced FMS intervention researchers/practitioners (N = 22) in the United Kingdom and Ireland. Participants generated and ranked barriers they perceive most critical in implementing FMS interventions. …”
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Estimating the environmental impacts of 57,000 food products by Clark, M, Scarborough, P, Springmann, M, Rayner, M, Hill, J, Tilman, D, Macdiarmid, JI, Fanzo, J, Bandy, L, Harrington, RA

“…Using the approach on 57,000 products in the United Kingdom and Ireland shows food types have low (e.g., sugary beverages, fruits, breads), to intermediate (e.g., many desserts, pastries), to high environmental impacts (e.g., meat, fish, cheese). …”

Manufacturing Mesenchymal Stromal Cells for the Treatment of Osteoarthritis in Canine Patients: Challenges and Recommendations by Ana Ivanovska, Mengyu Wang, Tarlan Eslami Arshaghi, Georgina Shaw, Joel Alves, Andrew Byrne, Steven Butterworth, Russell Chandler, Laura Cuddy, James Dunne, Shane Guerin, Rob Harry, Aidan McAlindan, Ronan A. Mullins, Frank Barry

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DAPK1 as an independent prognostic marker in liver cancer by Ling Li, Libin Guo, Qingshui Wang, Xiaolong Liu, Yongyi Zeng, Qing Wen, Shudong Zhang, Hang Fai Kwok, Yao Lin, Jingfeng Liu

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Development of a Gas-Tight Syringe Headspace GC-FID Method for the Detection of Ethanol, and a Description of the Legal and Practical Framework for Its Analysis, in Samples of Engl... by Luke Taylor, Lili Saskőy, Tara Brodie, Vytautas Remeškevičius, Hannah Jayne Moir, James Barker, John Fletcher, Baljit Kaur Thatti, Gavin Trotter, Brian Rooney

“…The validation of this technique complies with the recommended laboratory guidelines set out by United Kingdom and Ireland Association of Forensic Toxicologists (UKIAFT), the recently issued Laboratory 51 guidelines by the United Kingdom Accreditation Service (UKAS), and the criteria set out by the California Code of Regulations (CCR), 17 CCR § 1220.1.…”
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Development of a novel immunochromatographic lateral flow assay specific for Mycobacterium bovis cells and its application in combination with immunomagnetic separation to test bad... by Linda D. Stewart, Nuria Tort, Paul Meakin, Jose M. Argudo, Ruramayi Nzuma, Neil Reid, Richard J. Delahay, Roland Ashford, W. Ian Montgomery, Irene R. Grant

“…Abstract Background The European badger is an important wildlife reservoir of Mycobacterium bovis implicated in the spread of bovine tuberculosis in the United Kingdom and Ireland. Infected badgers are known to shed M. bovis in their urine and faeces, which may contaminate the environment. …”
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Biomarkers to assess the risk of bladder cancer in patients presenting with haematuria are gender-specific by Brian Duggan, Declan O’Rourke, Neil Anderson, Cherith N. Reid, Joanne Watt, Hugh O’Kane, Ruth Boyd, David Curry, Mark Evans, Michael Stevenson, Mary Jo Kurth, John V. Lamont, Peter Fitzgerald, Mark W. Ruddock

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Global Burden, Risk Factors, and Trends of Esophageal Cancer: An Analysis of Cancer Registries from 48 Countries by Junjie Huang, Anastasios Koulaouzidis, Wojciech Marlicz, Veeleah Lok, Cedric Chu, Chun Ho Ngai, Lin Zhang, Ping Chen, Shanjuan Wang, Jinqiu Yuan, Xiang-Qian Lao, Shelly L.A. Tse, Wanghong Xu, Zhi-Jie Zheng, Shao-Hua Xie, Martin C.S. Wong

“…The highest incidence of adenocarcinoma (AC) was found in the Netherlands, the United Kingdom, and Ireland. A higher AC/squamous cell carcinoma (SCC) incidence ratio was associated with a higher prevalence of obesity and elevated cholesterol. …”
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Genomic Surveillance of <named-content content-type="genus-species">Enterococcus faecium</named-content> Reveals Limited Sharing of Strains and Resistance Genes between Livestock a... by Theodore Gouliouris, Kathy E. Raven, Catherine Ludden, Beth Blane, Jukka Corander, Carolyne S. Horner, Juan Hernandez-Garcia, Paul Wood, Nazreen F. Hadjirin, Milorad Radakovic, Mark A. Holmes, Marcus de Goffau, Nicholas M. Brown, Julian Parkhill, Sharon J. Peacock

“…More than 600 isolates from these sources were sequenced, and their relatedness and antibiotic resistance genes were compared with genomes of almost 800 E. faecium isolates from patients with bloodstream infection in the United Kingdom and Ireland. E. faecium was isolated from 28/29 farms; none of these isolates were VREfm, suggesting a decrease in VREfm prevalence since the last UK livestock survey in 2003. …”
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Long-term trends in mortality and AIDS-defining events after combination ART initiation among children and adolescents with perinatal HIV infection in 17 middle- and high-income co... by European Pregnancy and Paediatric HIV Cohort Collaboration (EPPICC) study group in EuroCoord, Ali Judd, Elizabeth Chappell, Anna Turkova, Sophie Le Coeur, Antoni Noguera-Julian, Tessa Goetghebuer, Katja Doerholt, Luisa Galli, Dasja Pajkrt, Laura Marques, Intira J Collins, Diana M Gibb, Maria Isabel González Tome, Marisa Navarro, Josiane Warszawski, Christoph Königs, Vana Spoulou, Filipa Prata, Elena Chiappini, Lars Naver, Carlo Giaquinto, Claire Thorne, Magdalena Marczynska, Liubov Okhonskaia, Klara Posfay-Barbe, Pradthana Ounchanum, Pornchai Techakunakorn, Galina Kiseleva, Ruslan Malyuta, Alla Volokha, Luminita Ene, Ruth Goodall

“…Of 3,526 children included, 32% were from the United Kingdom or Ireland, 30% from elsewhere in W&CE, 18% from Russia or Ukraine, and 20% from Thailand. …”
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From empire to empire: The collapse of British America and the rise of imperial republicanism, 1773-1812 by Taylor, TD

“…Often historians of the Revolution restrict their study to the thirteen colonies which become the United States, but Continental Congress sent invitations to and envisioned delegates from throughout the British Empire from the Kingdom of Ireland to Barbados. Congress’s original goal was ‘to preserve the freedom and happiness of the whole British empire’. …”

Acute severe paediatric asthma: study protocol for the development of a core outcome set, a Pediatric Emergency Research Networks (PERN) study by Simon Craig, Franz E. Babl, Stuart R. Dalziel, Charmaine Gray, Colin Powell, Khalid Al Ansari, Mark D. Lyttle, Damian Roland, Javier Benito, Roberto Velasco, Julia Hoeffe, Diana Moldovan, Graham Thompson, Suzanne Schuh, Joseph J. Zorc, Maria Kwok, Prashant Mahajan, Michael D. Johnson, Robert Sapien, Kajal Khanna, Pedro Rino, Javier Prego, Adriana Yock, Ricardo M. Fernandes, Indumathy Santhanam, Baljit Cheema, Gene Ong, Shu-Ling Chong, Andis Graudins, On behalf of the Pediatric Emergency Research Networks (PERN)

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Natural history and outcomes in paediatric RASopathy‐associated hypertrophic cardiomyopathy by Olga Boleti, Gabrielle Norrish, Ella Field, Kathleen Dady, Kim Summers, Gauri Nepali, Vinay Bhole, Orhan Uzun, Amos Wong, Piers E. F. Daubeney, Graham Stuart, Precylia Fernandes, Karen McLeod, Maria Ilina, Muhammad Najih Liaqath Ali, Tara Bharucha, Grazia Delle Donne, Elspeth Brown, Katie Linter, Caroline B. Jones, Jonathan Searle, William Regan, Sujeev Mathur, Nicola Boyd, Zdenka Reinhardt, Sophie Duignan, Terence Prendiville, Satish Adwani, Juan Pablo Kaski

“…Methods and results This is a retrospective cohort study from 14 paediatric cardiology centres in the United Kingdom and Ireland. We included children <18 years with HCM and a clinical and/or genetic diagnosis of a RASopathy syndrome [Noonan syndrome (NS), NS with multiple lentigines (NSML), Costello syndrome (CS), cardiofaciocutaneous syndrome (CFCS), and NS with loose anagen hair (NS‐LAH)]. …”
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