Electroanalytical Overview: The Determination of Levodopa (L-DOPA) by Robert D. Crapnell, Craig E. Banks

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L-DOPA BIOSYNTHESIS WITH Agaricus bisporus TYROSINASES ASSISTANCE by Shesterenko Yu. A., Romanovska I. I., Shesterenko E. A.

Subjects: “…l-dopa synthesis…”
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L-dopa metabolism and the regulation of brain polysome aggregation by Weiss, Bette Fishman.

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Plasma concentrations of L-dopa and 3-methoxydopa and improvement in clinical ratings and motor performance in patients with Parkinsonism treated with L-dopa alone or in combination with amantadine. by Pilling, J, Baker, J, Iversen, L, Iversen, S, Robbins, T

“…Six patients with idiopathic Parkinsonism were treated with a combination of amantadine and L-dopa and after 12 to 24 weeks amantadine was replaced by placebo for a six week period in a double-blind trial. …”

Effects of hydrogen gas inhalation on L-DOPA-induced dyskinesia by Glauce C. Nascimento, Bruna M. Santos, João F. Pedrazzi, Danyelle Silva-Amaral, Mariza Bortolanza, Grant T. Harris, Elaine Del Bel, Luiz G.S. Branco

“…L-3,4-dihydroxyphenylalanine (L-DOPA)-induced dyskinesia is a side effect of Parkinson's disease treatment and it is characterized by atypical involuntary movements. …”
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Propranolol Relieves L-Dopa-Induced Dyskinesia in Parkinsonian Mice by Ziqing Shi, Ian J. Bamford, Jonathan W. McKinley, Suma Priya Sudarsana Devi, Annie Vahedipour, Nigel S. Bamford

“…Background: Parkinsonism is caused by dopamine (DA) insufficiency and results in a hypokinetic movement disorder. Treatment with L-Dopa can restore DA availability and improve motor function, but patients can develop L-Dopa-induced dyskinesia (LID), a secondary hyperkinetic movement disorder. …”
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Kinetic evaluation of L-Dopa loaded WGA-grafted nanoparticles by Sema Arisoy, Tansel Comoglu

“…In this study wheat germ agglutinin (WGA) conjugated, L-Dopa loaded, poly lactic-co-glycolic acid (PLGA) nanoparticles were analyzed for determining the release pattern of L-Dopa. …”
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Targeting Striatal Glutamate and Phosphodiesterases to Control L-DOPA-Induced Dyskinesia by Brik A. Kochoian, Cassandra Bure, Stella M. Papa

Subjects: “…L-DOPA-induced dyskinesia…”
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Receptor Ligands as Helping Hands to L-DOPA in the Treatment of Parkinson’s Disease by Fabio Del Bello, Mario Giannella, Gianfabio Giorgioni, Alessandro Piergentili, Wilma Quaglia

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L-DOPA enhances neural direction signals in younger and older adults by Christoph Koch, Christian Baeuchl, Franka Glöckner, Philipp Riedel, Johannes Petzold, Michael N. Smolka, Shu-Chen Li, Nicolas W. Schuck

“…We studied the effect of L-DOPA, a dopamine precursor, on fMRI activation patterns that encode spatial walking directions that have previously been shown to lose specificity with age. …”
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An Overview of Methods for L-Dopa Extraction and Analytical Determination in Plant Matrices by Carmen Tesoro, Filomena Lelario, Rosanna Ciriello, Giuliana Bianco, Angela Di Capua, Maria Assunta Acquavia

“…L-dopa is a precursor of dopamine used as the most effective symptomatic drug treatment for Parkinson’s disease. …”
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Nigrostriatal damage is required for induction of dyskinesias by L-DOPA in squirrel monkeys. by Boyce, S, Rupniak, N, Steventon, M, Iversen, S

“…These findings provide further evidence that nigrostriatal damage is essential for the genesis of L-DOPA-induced dyskinesias.…”

Characterisation of dyskinesias induced by L-dopa in MPTP-treated squirrel monkeys. by Boyce, S, Rupniak, N, Steventon, M, Iversen, S

“…Intermittent treatment with L-dopa over a 2-year period induced abnormal involuntary movements in MPTP-treated squirrel monkeys. …”

Expression of Human L-Dopa Decarboxylase (DDC) under Conditions of Oxidative Stress by Nikolaos S. Lotsios, Nikolaos Arvanitis, Alexandros G. Charonitakis, George Mpekoulis, Efseveia Frakolaki, Niki Vassilaki, Diamantis C. Sideris, Dido Vassilacopoulou

Subjects: “…L-Dopa decarboxylase…”
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Structural, Conformational and Spectroscopic Investigations of a Biologically Active Compound: L-Dopa by Rohit Kumar Yadav, Ram Anjore Yadav, Irena Kostova

“…Structural, conformational and spectroscopic investigations of the L-dopa molecule were made at the b3lyp/6-311++g** level using the Gaussian 09 software. …”
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Pyrylium based derivatization imaging mass spectrometer revealed the localization of L-DOPA. by Shu Taira, Akari Ikeda, Yuki Sugiura, Hitomi Shikano, Shoko Kobayashi, Tsutomu Terauchi, Jun Yokoyama

“…Simultaneous imaging of l-dihydroxyphenylalanine (l-DOPA), dopamine (DA) and norepinephrine (NE) in the catecholamine metabolic pathway is particularly useful because l-DOPA is a neurophysiologically important metabolic intermediate. …”
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Effect Of Epinephrine, Norepinephrine And L-Dopa On The Settlement And Metamorphosis Of Larvae Of Crassostrea Gigas by L. McAnally-Salas, H. Carvazos-Lliteras, A. Salas-Garza

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Involvement of the L-DOPA receptor GPR143 in acute and chronic actions of methylphenidate by Hiraku Uchimura, Kaori Kanai, Masami Arai, Miyu Inoue, Akitoyo Hishimoto, Daiki Masukawa, Yoshio Goshima

Subjects: “…L-DOPA…”
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Fear extinction rescuing effects of dopamine and L-DOPA in the ventromedial prefrontal cortex by Simone B. Sartori, Thomas M. V. Keil, Kai K. Kummer, Conor P. Murphy, Ozge Gunduz-Cinar, Michaela Kress, Karl Ebner, Andrew Holmes, Nicolas Singewald

“…Systemic L-DOPA enabled extinction learning and promoted extinction retention at one but not ten days after training. …”
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l‐Dopa responsiveness is associated with distinctive connectivity patterns in advanced Parkinson's disease by Akram, H, Wu, C, Hyam, J, Foltynie, T, Limousin, P, De Vita, E, Yousry, T, Jahanshahi, M, Hariz, M, Behrens, T, Ashburner, J, Zrinzo, L

“…CONCLUSIONS:Our findings show characteristic basal ganglia resting-state functional connectivity patterns associated with different degrees of l-dopa responsiveness in patients with advanced Parkinson's disease. l-Dopa exerts a graduated influence on remapping connectivity in distinct motor control networks, potentially explaining some of the variance in treatment response. © 2017 International Parkinson and Movement Disorder Society.…”