LSD1 inhibition modulates transcription factor networks in myeloid malignancies by Emily E. Hartung, Emily E. Hartung, Kanwaldeep Singh, Kanwaldeep Singh, Tobias Berg, Tobias Berg, Tobias Berg

Subjects: “…lysine specific demethylase 1 (LSD1)…”
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Lsd1 Ablation Triggers Metabolic Reprogramming of Brown Adipose Tissue by Delphine Duteil, Milica Tosic, Franziska Lausecker, Hatice Z. Nenseth, Judith M. Müller, Sylvia Urban, Dominica Willmann, Kerstin Petroll, Nadia Messaddeq, Laura Arrigoni, Thomas Manke, Jan-Wilhelm Kornfeld, Jens C. Brüning, Vyacheslav Zagoriy, Michael Meret, Jörn Dengjel, Toufike Kanouni, Roland Schüle

“…Here we investigate the role of Lsd1 in brown adipose tissue (BAT) and find that BAT-selective Lsd1 ablation induces a shift from oxidative to glycolytic metabolism. …”
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A Scientific Document Retrieval and Reordering Method by Incorporating HFS and LSD by Ziyang Feng, Xuedong Tian

“…To solve this problem, this paper proposes a scientific document retrieval method founded upon hesitant fuzzy sets (HFS) and local semantic distillation (LSD). Concretely, in order to extract both spatial and semantic features for each symbol within a mathematical expression, this paper introduces an expression analysis module that leverages HFS to establish feature indices. …”
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Experiências com a dietilamina do ácido lisérgico (LSD 25) by Paulo Luiz Vianna Guedes

“…São relatados os resultados de 5 experiências realizadas em 3 pacientes com LSD 25, sendo salientadas as propriedades terapêuticas dêste medicamento como auxiliar da psicoterapia. …”
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A non-hallucinogenic LSD analog with therapeutic potential for mood disorders by Vern Lewis, Emma M. Bonniwell, Janelle K. Lanham, Abdi Ghaffari, Hooshmand Sheshbaradaran, Andrew B. Cao, Maggie M. Calkins, Mario Alberto Bautista-Carro, Emily Arsenault, Andre Telfer, Fatimeh-Frouh Taghavi-Abkuh, Nicholas J. Malcolm, Fatema El Sayegh, Alfonso Abizaid, Yasmin Schmid, Kathleen Morton, Adam L. Halberstadt, Argel Aguilar-Valles, John D. McCorvy

“…Here we profiled the non-hallucinogenic lysergic acid diethylamide (LSD) analog 2-bromo-LSD (2-Br-LSD) at more than 33 aminergic G protein-coupled receptors (GPCRs). 2-Br-LSD shows partial agonism at several aminergic GPCRs, including 5-HT2A, and does not induce the head-twitch response (HTR) in mice, supporting its classification as a non-hallucinogenic 5-HT2A partial agonist. …”
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Acute effects of lysergic acid diethylamide (LSD) on resting brain function by Felix Müller, Stefan Borgwardt

Subjects: “…lysergic acid diethylamide (LSD)…”
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LSD1 inhibitors disrupt the GFI1 transcription repressor complex by Alba Maiques-Diaz, James T. Lynch, Gary J. Spencer, Tim C.P. Somervaille

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Expanding the Role of the Histone Lysine-Specific Demethylase LSD1 in Cancer by Barbara Majello, Francesca Gorini, Carmen Daniela Saccà, Stefano Amente

Subjects: “…LSD1…”
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Anxiety and depression symptoms in Brazilian sexual minority ecstasy and LSD users by Lysa S. Remy, Juliana Scherer, Luciano Guimarães, Hilary L. Surratt, Steven P. Kurtz, Flavio Pechansky, Felix Kessler

“…Abstract Background This study examined drug use patterns and psychiatric symptoms of anxiety and depression among young Brazilian sexual minority ecstasy and LSD users and compared findings with those reported for their heterosexual peers. …”
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Roles of lysine-specific demethylase 1 (LSD1) in homeostasis and diseases by Dongha Kim, Keun Il Kim, Sung Hee Baek

“…Abstract Lysine-specific demethylase 1 (LSD1) targets mono- or di-methylated histone H3K4 and H3K9 as well as non-histone substrates and functions in the regulation of gene expression as a transcriptional repressor or activator. …”
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LSD1 is an environmental stress-sensitive negative modulator of the glutamatergic synapse by A. Longaretti, C. Forastieri, E. Toffolo, L. Caffino, A. Locarno, I. Misevičiūtė, E. Marchesi, M. Battistin, L. Ponzoni, L. Madaschi, C. Cambria, M.P. Bonasoni, M. Sala, D. Perrone, F. Fumagalli, S. Bassani, F. Antonucci, R. Tonini, M. Francolini, E. Battaglioli, F. Rusconi

Subjects: “…LSD1/KDM1A…”
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Novel dual LSD1/HDAC6 inhibitor for the treatment of cancer. by Chandru Gajendran, Subramanyam Janardhan Tantry, Naveen Sadhu M, Zainuddin Mohammed, Purushottam Dewang, Mahanandeesha Hallur, Sreekala Nair, Krishnakumar Vaithilingam, Basavaprabhu Nagayya, Sridharan Rajagopal, Dhanalakshmi Sivanandhan

“…Here, we evaluated JBI-097 a dual LSD1/HDAC6 inhibitor, for its in vitro and in vivo activities in various tumor models. …”
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LSD 4.0: an improved database for comparative studies of leaf senescence by Jie Cao, Yang Zhang, Shuya Tan, Qi Yang, Hou-Ling Wang, Xinli Xia, Jingchu Luo, Hongwei Guo, Zhang Zhang, Zhonghai Li

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LSD1 Facilitates Pro-Inflammatory Polarization of Macrophages by Repressing Catalase by Maciej Sobczak, Magdalena Strachowska, Karolina Gronkowska, Iwona Karwaciak, Łukasz Pułaski, Agnieszka Robaszkiewicz

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Stability studies of ALD-52 and its homologue 1P-LSD by Zhang, Shu-Hua, Tang, Angeline S. Y., Chin, Reenie S. L., Goh, Jia Ying, Ong, Mei Ching, Lim, Wendy J. L., Yap, Angeline T. W., So, Cheuk-Wai

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Targeting Histone Demethylase LSD1/KDM1a in Neurodegenerative Diseases by Susanna Ambrosio, Barbara Majello

“…LSD1 binds to the promoter region of the SESN2 gene, where LSD1-mediated demethylation leads to the accumulation of repressive histone marks that maintain SESN2 expression at low levels. …”
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Demethylase-independent roles of LSD1 in regulating enhancers and cell fate transition by Cheng Zeng, Jiwei Chen, Emmalee W. Cooke, Arijita Subuddhi, Eliana T. Roodman, Fei Xavier Chen, Kaixiang Cao

“…LSD1 deletion increases H3K27ac levels and P300 occupancy at LSD1-targeted enhancers. …”
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Lsd1 regulates skeletal muscle regeneration and directs the fate of satellite cells by Milica Tosic, Anita Allen, Dominica Willmann, Christoph Lepper, Johnny Kim, Delphine Duteil, Roland Schüle

“…Here, the authors show that the histone demethylase Lsd1 prevents adipogenic differentiation of satellite cells by repressing expression of Glis1, and that its ablation changes satellite cell fate towards brown adipocytes and delays muscle regeneration in mice.…”
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Elevated LSD1 and SNAIL Expression Indicate Poor Prognosis in Hypopharynx Carcinoma by Justus Bottner, Julika Ribbat-Idel, Luise Klapper, Tobias Jagomast, Anna-Lena Lemster, Sven Perner, Christian Idel, Jutta Kirfel

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KDM1A/LSD1 regulates the differentiation and maintenance of spermatogonia in mice. by Dexter A Myrick, Michael A Christopher, Alyssa M Scott, Ashley K Simon, Paul G Donlin-Asp, William G Kelly, David J Katz

“…Here, we investigated the function of the H3K4me2 demethylase KDM1A/LSD1 during spermatogenesis in developing and adult mice. …”
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