Comprehensive Evaluation of the m6A Regulator Prognostic Risk Score in the Prediction of Immunotherapy Response in Clear Cell Renal Cell Carcinoma by Mingke Yu, Mingke Yu, Xuefei Liu, Han Xu, Sangyu Shen, Fajiu Wang, Dajin Chen, Guorong Li, Zongping Wang, Zhixiang Zuo, An Zhao, An Zhao

“…The 8 regulator genes with minimal lambda were integrated to build an MRPRS, and it was positively correlated with immunotherapeutic response in extent validation cohorts. …”
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Single-Cell Approach Reveals Intercellular Heterogeneity in Phage-Producing Capacities by Sherin Kannoly, Gabriella Oken, Jonathan Shadan, David Musheyev, Kevin Singh, Abhyudai Singh, John J. Dennehy

“…In this study, we estimated the bacteriophage lambda (λ) single-cell burst size mean and variance following different intracellular accumulation period durations by employing Escherichia coli lysogens bearing lysis-deficient λ prophages. …”
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A SEVA-based, CRISPR-Cas3-assisted genome engineering approach for Pseudomonas with efficient vector curing by Eveline-Marie Lammens, Daniel Christophe Volke, Kaat Schroven, Marleen Voet, Alison Kerremans, Rob Lavigne, Hanne Hendrix

“…However, the Cas9 system does not allow efficient genomic integration in Pseudomonas putida, an emerging Synthetic Biology host, without the assistance of lambda-Red recombineering. In this work, we utilize the alternative Class I Type I-C CRISPR-Cas3 system from Pseudomonas aeruginosa as a highly efficient genome editing tool for P. putida and P. aeruginosa. …”
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An Aperture-Coupled-Cross-Resonator FSS Based Spatial Filtering Patch Antenna Array by Ye Li, Xuran Nie, Xinmi Yang, Changrong Liu, Xianqi Lin, Kemeng Huang

“…A low-profile spatial filtering patch array (LPSFPA) with thickness of <inline-formula> <tex-math notation="LaTeX">$0.07\lambda _{0}$ </tex-math></inline-formula> and operating around 3.6GHz is constructed by placing an asymmetrical ACCR FSS tightly upon a patch antenna array with a half-period lateral shift. …”
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Dirichlet problems involving the Hardy-Leray operators with multiple polars by Chen Huyuan, Chen Xiaowei

“…First, we obtain increasing Dirichlet eigenvalues: ℒVu=λuinΩ,u=0on∂Ω,{{\mathcal{ {\mathcal L} }}}_{V}u=\lambda u\hspace{1.0em}{\rm{in}}\hspace{0.33em}\Omega ,\hspace{1.0em}u=0\hspace{1.0em}{\rm{on}}\hspace{0.33em}\partial \Omega , and the positivity of the principle eigenvalue depends on the strength μi{\mu }_{i} and polars’ setting. …”
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Development of Multifunctional Liposomes Containing Magnetic/Plasmonic MnFe2O4/Au Core/Shell Nanoparticles by Ana Rita O. Rodrigues, Joana O. G. Matos, Armando M. Nova Dias, Bernardo G. Almeida, Ana Pires, André M. Pereira, João P. Araújo, Maria-João R. P. Queiroz, Elisabete M. S. Castanheira, Paulo J. G. Coutinho

“…The core/shell nanoparticles exhibit sizes of 25 &plusmn; 2 nm (from TEM), a plasmonic absorption band (&lambda;max = 550 nm), and keep magnetic character. …”
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Immunoinformatic exploration of a multi-epitope-based peptide vaccine candidate targeting emerging variants of SARS-CoV-2 by K. M. Kumar, Yalpi Karthik, D. Ramakrishna, S. Balaji, Sinosh Skariyachan, T. P. Krishna Murthy, Kunnathur Murugesan Sakthivel, Badriyah S. Alotaibi, Mustafa Shukry, Samy M. Sayed, Samy M. Sayed, Muntazir Mushtaq

“…Our study attempted to predict an MEBP vaccine by introducing mutations of SARS-CoV-2 (Delta, Lambda, Iota, Omicron, and Kappa) in Spike glycoprotein and predicting dual-purpose epitopes (B-cell and T-cell). …”
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Health systems strengthening through policy-level integration of community health worker programs into national health systems for improved health outcomes - scorecard metrics vali... by Lucia Mungapeyi Mupara, John Jules O. Mogaka, William R. Brieger, Joyce M. Tsoka-Gwegweni, Joyce M. Tsoka-Gwegweni

“…Cronbach's alpha (α), Guttman 6 (Lambda 6), and Omega total (ωt) were above 0.8, indicating good scale reliability.ConclusionStatistical significance of the bifactor model suggests that CHW integration has to be examined using factors that reflect a single common underlying integration construct, as well as factors that reflect unique variances for the identified six subject-specific domains. …”
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Lean-burn characteristics of a gasoline engine enriched with hydrogen from a plasmatron fuel reformer by Tully, Edward J. (Edward Joseph), 1975-

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Terahertz imaging and quantum cascade laser based devices by Lee, Alan Wei Min

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Common Genetic Variants and Modification of Penetrance of BRCA2-Associated Breast Cancer by Green, Todd, Guiducci, Candace, Segre, Ayellet V., Daly, Mark J., Altshuler, David, Korn, Joshua M.

“…The genomic inflation factor (lambda) was 1.011. The stage 1 association analysis revealed multiple variants associated with breast cancer risk: 3 SNPs had p-values<10[superscript -5] and 39 SNPs had p-values<10[superscript -4]. …”
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Polariton lasing in Mie-resonant perovskite nanocavity by Masharin, Mikhail A., Khmelevskaia, Daria, Kondratiev, Valeriy I., Markina, Daria I., Utyushev, Anton D., Dolgintsev, Dmitriy M., Dmitriev, Alexey D., Shahnazaryan, Vanik A., Pushkarev, Anatoly P., Isik, Furkan, Iorsh, Ivan V., Shelykh, Ivan A., Demir, Hilmi Volkan, Samusev, Anton K., Makarov, Sergey V.

“…Here we exploit exciton-polariton condensation and mirror-image Mie modes in a cuboid CsPbBr$_3$ nanoparticle to achieve coherent emission at the visible wavelength of around 0.53~$\mu $m from its ultra-small ($\approx$0.007$\mu$m$^3$ or $\approx\lambda^3$/20) semiconductor nanocavity. The polaritonic nature of the emission from the nanocavity localized in all three dimensions is proven by direct comparison with corresponding one-dimensional and two-dimensional waveguiding systems with similar material parameters. …”
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TDCOSMO: XII. Improved Hubble constant measurement from lensing time delays using spatially resolved stellar kinematics of the lens galaxy by Shajib, AJ, Mozumdar, P, Chen, GCF, Treu, T, Cappellari, M, Knabel, S, Suyu, SH, Bennert, VN, Frieman, JA, Sluse, D, Birrer, S, Courbin, F, Fassnacht, CD, Villafaña, L, Williams, PR

“…Following a blind analysis, we estimated the angular diameter distance to the lens galaxy&nbsp;<em>D</em>_d = 865_&minus;81⁺⁸⁵&nbsp;Mpc and the time-delay distance&nbsp;<em>D</em>_&Delta;t = 2180_&minus;271⁺⁴⁷²&nbsp;Mpc, giving&nbsp;<em>H</em>₀ = 77.1_&minus;7.1^+7.3&nbsp;km s^&minus;1&nbsp;Mpc^&minus;1&nbsp;&ndash; for a flat &Lambda; cold dark matter cosmology. The error budget accounts for all uncertainties, including the MSD inherent to the lens mass profile and line-of-sight effects, and those related to the mass&ndash;anisotropy degeneracy and projection effects. …”

Development of reverse transcription loop-mediated isothermal amplification for rapid detection of Sars-Cov-2 by Attah, Obande Godwin

“…Based on in silico analysis, the RT-LAMP primers could also detect Alpha, Beta, Delta, Gamma, Lambda and Mu SARS-CoV-2 variants from within and outside Malaysia. …”
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The Near-infrared Ca ii Triplet as a Stellar Activity Indicator: A Library and Comparative Study by Xin Huang, Yuji He, Zhongrui Bai, Hailong Yuan, Mingkuan Yang, Ming Zhou, Yiqiao Dong, Mengxin Wang, Han He, Jinghua Zhang, Yaoquan Chu, Yongheng Zhao, Yong Zhang, Haotong Zhang

“…We compared the differences between the three individual indices of the Ca ii triplet and also conducted a comparative analysis of ${R}_{\lambda 8542}^{+}$ to the Ca ii H and K S and ${R}_{\mathrm{HK}}^{+}$ index databases. …”
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Field-level Neural Network Emulator for Cosmological N-body Simulations by Drew Jamieson, Yin Li, Renan Alves de Oliveira, Francisco Villaescusa-Navarro, Shirley Ho, David N. Spergel

“…Cosmology dependence is encoded in the form of style parameters at each layer of the neural network, enabling the emulator to effectively interpolate the outcomes of structure formation between different flat Lambda cold dark matter cosmologies over a wide range of background matter densities. …”
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Composition and Long-Term Variation Characteristics of Coral Reef Fish Species in Yongle Atoll, Xisha Islands, China by Jinfa Zhao, Chunhou Li, Teng Wang, Juan Shi, Xiaoyu Song, Yong Liu

“…The average taxonomic distinctness (Delta+, Δ+) and the variation taxonomic distinctness (Lambda+, Λ+) in 2020–2022 were lower than the historical data, and the number of fish orders, families, and genera in Yongle Atoll has decreased significantly, which indicates that the current coral reef fish species in Yongle Atoll have closer relatives and higher fish species uniformity. …”
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Antagonism of dsRNA-Induced Innate Immune Pathways by NS4a and NS4b Accessory Proteins during MERS Coronavirus Infection by Courtney E. Comar, Stephen A. Goldstein, Yize Li, Boyd Yount, Ralph S. Baric, Susan R. Weiss

“…We found that deletion of NS4a results in increased interferon lambda (IFNL1) expression, as does mutation of either the catalytic site or nuclear localization sequence of NS4b. …”
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SARS-CoV-2 fusion-inhibitory lipopeptides maintain high potency against divergent variants of concern including Omicron by Yuanmei Zhu, Xiaojing Dong, Nian Liu, Tong Wu, Huihui Chong, Xiaobo Lei, Lili Ren, Jianwei Wang, Yuxian He

“…First, we found that pseudoviruses bearing the S proteins of five VOCs (Alpha, Beta, Gamma, Delta, and Omicron) and one variant of interest (Lambda) exhibited greatly decreased infectivity relative to the wild-type (WT) strain or single D614G mutant, especially the Omicron pseudovirus. …”
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Circuit Analysis of a Coplanar Waveguide (CPW) Terminated With a Step-Impedance Resonator (SIR) for Highly Sensitive One-Port Permittivity Sensing by Pau Casacuberta, Paris Velez, Jonathan Munoz-Enano, Lijuan Su, Marta Gil Barba, Amir Ebrahimi, Ferran Martin

“…The maximum sensitivity in one of the reported sensors is as high as 66.5&#x00B0;, and the main figure of merit, defined as the ratio between the maximum sensitivity and the area of the sensing region expressed in terms of the squared guided wavelength, is <inline-formula> <tex-math notation="LaTeX">$\text {FoM} = 3643^{\circ }/\lambda ^{2}$ </tex-math></inline-formula>. Such figure of merit represents a significant improvement as compared to the one of the equivalent sensor implemented by means of an open-ended quarter-wavelength sensing line. …”
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