Structural basis for delta cell paracrine regulation in pancreatic islets by Rafael Arrojo e Drigo, Stefan Jacob, Concha F. García-Prieto, Xiaofeng Zheng, Masahiro Fukuda, Hoa Tran Thi Nhu, Olga Stelmashenko, Flavia Letícia Martins Peçanha, Rayner Rodriguez-Diaz, Eric Bushong, Thomas Deerinck, Sebastien Phan, Yusuf Ali, Ingo Leibiger, Minni Chua, Thomas Boudier, Sang-Ho Song, Martin Graf, George J. Augustine, Mark H. Ellisman, Per-Olof Berggren

Get full text

Author Correction: Structural basis for delta cell paracrine regulation in pancreatic islets by Rafael Arrojo e Drigo, Stefan Jacob, Concha F. García-Prieto, Xiaofeng Zheng, Masahiro Fukuda, Hoa Tran Thi Nhu, Olga Stelmashenko, Flavia Letícia Martins Peçanha, Rayner Rodriguez-Diaz, Eric Bushong, Thomas Deerinck, Sebastien Phan, Yusuf Ali, Ingo Leibiger, Minni Chua, Thomas Boudier, Sang-Ho Song, Martin Graf, George J. Augustine, Mark H. Ellisman, Per-Olof Berggren

Get full text

Visualization of accessible cholesterol using a GRAM domain-based biosensor by Dylan Hong Zheng Koh, Tomoki Naito, Minyoung Na, Yee Jie Yeap, Pritisha Rozario, Franklin L. Zhong, Kah-Leong Lim, Yasunori Saheki

Get full text

Bacteria evoke alarm behaviour in zebrafish by Joanne Shu Ming Chia, Elena S. Wall, Caroline Lei Wee, Thomas A. J. Rowland, Ruey-Kuang Cheng, Kathleen Cheow, Karen Guillemin, Suresh Jesuthasan

Get full text

Obstacles for T-lymphocytes in the tumour microenvironment: Therapeutic challenges, advances and opportunities beyond immune checkpoint by Navin Kumar Verma, Brandon Han Siang Wong, Zhi Sheng Poh, Aiswarya Udayakumar, Ritu Verma, Ryan Kwang Jin Goh, Shane P. Duggan, Vishalkumar G. Shelat, K. George Chandy, Nicholas Francis Grigoropoulos

Get full text

Adiposity impacts cognitive function in Asian populations: an epidemiological and Mendelian Randomization studyResearch in context by Theresia Mina, Yik Weng Yew, Hong Kiat Ng, Nilanjana Sadhu, Gervais Wansaicheong, Rinkoo Dalan, Dorrain Yan Wen Low, Benjamin Chih Chiang Lam, Elio Riboli, Eng Sing Lee, Joanne Ngeow, Paul Elliott, Konstadina Griva, Marie Loh, Jimmy Lee, John Chambers

“…Funding: The Nanyang Technological University—the Lee Kong Chian School of Medicine, National Healthcare Group, National Medical Research Council, Ministry of Education, Singapore.…”
Get full text

Erratum for Vidaillac et al. “Sex Steroids Induce Membrane Stress Responses and Virulence Properties in <named-content content-type="genus-species">Pseudomonas aeruginosa</named-co... by Celine Vidaillac, Valerie Fei Lee Yong, Marie-Stephanie Aschtgen, Jing Qu, Shuowei Yang, Guangfu Xu, Zi Jing Seng, Alexandra C. Brown, Md Khadem Ali, Tavleen K. Jaggi, Jagadish Sankaran, Yong Hwee Foo, Francesco Righetti, Anu Maashaa Nedumaran, Micheál Mac Aogáin, Dan Roizman, Jean-Alexandre Richard, Thomas R. Rogers, Masanori Toyofuku, Dahai Luo, Edmund Loh, Thorsten Wohland, Bertrand Czarny, Jay C. Horvat, Philip M. Hansbro, Liang Yang, Liang Li, Staffan Normark, Birgitta Henriques-Normark, Sanjay H. Chotirmall

Get full text

Data pre-processing for analyzing microbiome data – A mini review by Ruwen Zhou, Siu Kin Ng, Joseph Jao Yiu Sung, Wilson Wen Bin Goh, Sunny Hei Wong

Get full text

CREB-regulated transcription during glycogen synthesis in astrocytes by Wei Lee Lim, Jessica Ruth Gaunt, Jia Min Tan, Norliyana Zainolabidin, Vibhavari Aysha Bansal, Yi Ming Lye, Toh Hean Ch’ng

Get full text

The LIDPAD Mouse Model Captures the Multisystem Interactions and Extrahepatic Complications in MASLD by Zun Siong Low, Damien Chua, Hong Sheng Cheng, Rachel Tee, Wei Ren Tan, Christopher Ball, Norliza Binte Esmail Sahib, Ser Sue Ng, Jing Qu, Yingzi Liu, Haiyu Hong, Chaonong Cai, Nandini Chilagondanahalli Lakshmi Rao, Aileen Wee, Mark Dhinesh Muthiah, Zoë Bichler, Barbara Mickelson, Mei Suen Kong, Vanessa Shiyun Tay, Zhuang Yan, Jiapeng Chen, Aik Seng Ng, Yun Sheng Yip, Marcus Ivan Gerard Vos, Nicole Ashley Tan, Dao Liang Lim, Debbie Xiu En Lim, Manesh Chittezhath, Jadegoud Yaligar, Sanjay Kumar Verma, Harish Poptani, Xue Li Guan, Sambasivam Sendhil Velan, Yusuf Ali, Liang Li, Nguan Soon Tan, Walter Wahli

Get full text

Lysosomal acidification dysfunction in microglia: an emerging pathogenic mechanism of neuroinflammation and neurodegeneration by Joseph D. Quick, Cristian Silva, Jia Hui Wong, Kah Leong Lim, Richard Reynolds, Anna M. Barron, Jialiu Zeng, Chih Hung Lo

Get full text

The habenula clock influences response to a stressor by Adriana Basnakova, Ruey-Kuang Cheng, Joanne Shu Ming Chia, Giuseppe D'Agostino, Suryadi, Germaine Jia Hui Tan, Sarah R. Langley, Suresh Jesuthasan

Get full text

Centrosome- and Golgi-Localized Protein Kinase N-Associated Protein Serves As a Docking Platform for Protein Kinase A Signaling and Microtubule Nucleation in Migrating T-Cells by Seow Theng Ong, Madhavi Latha Somaraju Chalasani, M. H. U. Turabe Fazil, Praseetha Prasannan, Atish Kizhakeyil, Graham D. Wright, Dermot Kelleher, Dermot Kelleher, Dermot Kelleher, Navin Kumar Verma, Navin Kumar Verma

Get full text

Alzheimer's Disease Blood Biomarkers Associated With Neuroinflammation as Therapeutic Targets for Early Personalized Intervention by Sher Li Oh, Sher Li Oh, Meikun Zhou, Eunice W. M. Chin, Gautami Amarnath, Chee Hoe Cheah, Kok Pin Ng, Kok Pin Ng, Kok Pin Ng, Nagaendran Kandiah, Eyleen L. K. Goh, Keng-Hwee Chiam

Get full text

The establishment of COPD organoids to study host-pathogen interaction reveals enhanced viral fitness of SARS-CoV-2 in bronchi by Louisa L. Y. Chan, Danielle E. Anderson, Hong Sheng Cheng, Fransiskus Xaverius Ivan, Si Chen, Adrian E. Z. Kang, Randy Foo, Akshamal M. Gamage, Pei Yee Tiew, Mariko Siyue Koh, Ken Cheah Hooi Lee, Kristy Nichol, Prabuddha S. Pathinayake, Yik Lung Chan, Tsin Wen Yeo, Brian G. Oliver, Peter A. B. Wark, Linbo Liu, Nguan Soon Tan, Lin-Fa Wang, Sanjay H. Chotirmall

Get full text

Myeloperoxidase inhibition may protect against endothelial glycocalyx shedding induced by COVID-19 plasma by Andrew Teo, Louisa L. Y. Chan, Christine Cheung, Po Ying Chia, Sean Wei Xiang Ong, Siew Wai Fong, Lisa F. P. Ng, Laurent Renia, David Chien Lye, Barnaby Edward Young, Tsin Wen Yeo

Get full text

Melatonin and health: an umbrella review of health outcomes and biological mechanisms of action by Pawel P. Posadzki, Ram Bajpai, Bhone Myint Kyaw, Nicola J. Roberts, Amnon Brzezinski, George I. Christopoulos, Ushashree Divakar, Shweta Bajpai, Michael Soljak, Gerard Dunleavy, Krister Jarbrink, Ei Ei Khaing Nang, Chee Kiong Soh, Josip Car

Get full text

Multifunctional Nanoparticles and Nanoclusters as a Theranostics and Symptoms Disappearing Agent for Traumatic Brain Injury by Fong LaiGuan Zoey, Krishna Kanta Ghosh, Mathangi Palanivel, Balázs Gulyás, Parasuraman Padmanabhan

Get full text

Gut-muscle crosstalk. A perspective on influence of microbes on muscle function by Weixuan Chew, Weixuan Chew, Yen Peng Lim, Yen Peng Lim, Wee Shiong Lim, Wee Shiong Lim, Wee Shiong Lim, Edward S. Chambers, Gary Frost, Sunny Hei Wong, Sunny Hei Wong, Sunny Hei Wong, Yusuf Ali, Yusuf Ali, Yusuf Ali, Yusuf Ali

Get full text

Student assistantship programme: an evaluation of impact on readiness to transit from medical student to junior doctor by Aloysius Chow, Shiwei Chen, Lucy Rosby, Naomi Low-Beer, Vishalkumar Girishchandra Shelat, Jennifer Cleland, Bernadette Bartlam, Helen Elizabeth Smith

“…One such intervention is the assistantship, which provides hands-on opportunities to hone clinical skills and undertake responsibilities under supervision. The Lee Kong Chian School of Medicine (LKCMed) is Singapore’s newest medical school, and students undergo a Student Assistantship Programme (SAP) to prepare for practice as junior doctors (PGY1). …”
Get full text