OA2-1 Frequent and ‘burst-like’ reactivation from latency in SIVmac239M infected macaques by M. Pinkevych, A. Reynaldi, C. Fennessey, C. Reid, P. Nadella, L. Lipkey, L. Newman, V. Ayala, S. Jain, G. Del Prete, J. Estes, D. Ott, J. Lifson, C. Ohlen, B. Keele, M. Davenport

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KRAS interaction with RAF1 RAS-binding domain and cysteine-rich domain provides insights into RAS-mediated RAF activation by Timothy H. Tran, Albert H. Chan, Lucy C. Young, Lakshman Bindu, Chris Neale, Simon Messing, Srisathiyanarayanan Dharmaiah, Troy Taylor, John-Paul Denson, Dominic Esposito, Dwight V. Nissley, Andrew G. Stephen, Frank McCormick, Dhirendra K. Simanshu

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PP 2.15 – 00169 Macrophages are the primary source of virus in semen and male genital tract organs in acutely and chronically infected rhesus macaques by C. Deleage, C. Fennessey, J. Harper, S. Florea, L. Lipkey, R. Fast, M. Paiardini, J. Lifson, B. Keele

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Reduced dynamic complexity allows structure elucidation of an excited state of KRASG13D by Fa-An Chao, Albert H. Chan, Srisathiyanarayanan Dharmaiah, Charles D. Schwieters, Timothy H. Tran, Troy Taylor, Nitya Ramakrishnan, Dominic Esposito, Dwight V. Nissley, Frank McCormick, Dhirendra K. Simanshu, Gabriel Cornilescu

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Clones of SIV-infected cells are present in spleen and lymph nodes in rhesus macaques by S.H. Hughes, A.L. Ferris, G.Q. Del Prete, B.F. Keele, X. Wu, J.D. Lifson

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Kaposi’s sarcoma-associated herpesvirus T cell responses in HIV seronegative individuals from rural Uganda by Angela Nalwoga, Romin Roshan, Kyle Moore, Vickie Marshall, Wendell Miley, Nazzarena Labo, Marjorie Nakibuule, Stephen Cose, Rosemary Rochford, Robert Newton, Denise Whitby

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Correction to: An analytical pipeline for identifying and mapping the integration sites of HIV and other retroviruses by Daria W. Wells, Shuang Guo, Wei Shao, Michael J. Bale, John M. Coffin, Stephen H. Hughes, Xiaolin Wu

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Crystal structure of the catalytic domain of HIV-1 restriction factor APOBEC3G in complex with ssDNA by Atanu Maiti, Wazo Myint, Tapan Kanai, Krista Delviks-Frankenberry, Christina Sierra Rodriguez, Vinay K. Pathak, Celia A. Schiffer, Hiroshi Matsuo

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RAS Nanoclusters: Dynamic Signaling Platforms Amenable to Therapeutic Intervention by Que N. Van, Priyanka Prakash, Rebika Shrestha, Trent E. Balius, Thomas J. Turbyville, Andrew G. Stephen

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Differential Effector Engagement by Oncogenic KRAS by Tina L. Yuan, Arnaud Amzallag, Rachel Bagni, Ming Yi, Shervin Afghani, William Burgan, Nicole Fer, Leslie A. Strathern, Katie Powell, Brian Smith, Andrew M. Waters, David Drubin, Ty Thomson, Rosy Liao, Patricia Greninger, Giovanna T. Stein, Ellen Murchie, Eliane Cortez, Regina K. Egan, Lauren Procter, Matthew Bess, Kwong Tai Cheng, Chih-Shia Lee, Liam Changwoo Lee, Christof Fellmann, Robert Stephens, Ji Luo, Scott W. Lowe, Cyril H. Benes, Frank McCormick

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Recapitulation of cell-like KRAS4b membrane dynamics on complex biomimetic membranes by Rebika Shrestha, De Chen, Peter Frank, Dwight V. Nissley, Thomas J. Turbyville

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Defining HIV and SIV Reservoirs in Lymphoid Tissues by Claire Deleage, Stephen W. Wietgrefe, Gregory Del Prete, David R. Morcock, Xing-Pei Hao, Michael Piatak, Jr., Julian Bess, Jodi L. Anderson, Katherine Perkey, Cavan Reilly, Joseph M. McCune, Ashley T. Haase, Jeffrey D. Lifson, Timothy W. Schacker, Jacob D. Estes

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Treatment with native heterodimeric IL-15 increases cytotoxic lymphocytes in lymph nodes and reduces SHIV RNA by G. Pavlakis, D.C. Watson, E. Moysi, A. Valentin, C. Bergamaschi, S. Devasundaram, S.P. Fortis, J. Bear, E. Chertova, J. Bess, Jr., R. Sowder, D.J. Venzon, C. Deleage, J.D. Estes, J.D. Lifson, C. Petrovas, B.K. Felber

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Low-cost HPV testing and the prevalence of cervical infection in asymptomatic populations in Guatemala by Hong Lou, Eduardo Gharzouzi, Sarita Polo Guerra, Joël Fokom Domgue, Julie Sawitzke, Guillermo Villagran, Lisa Garland, Joseph F. Boland, Sarah Wagner, Héctor Rosas, Jami Troxler, Heidi McMillen, Bailey Kessing, Enrique Alvirez, Miriam Castillo, Hesler Morales, Victor Argueta, Andert Rosingh, Femke J. H. B. van Aerde-van Nunen, Griselda Lopez, Herbert M. Pinedo, Mark Schiffman, Michael Dean, Roberto Orozco

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The contribution of host genetics and environmental variation to immune response in gamma-herpesvirus infections by N. Sallah, W. Miley, N. Labo, T. Carstensen, D. Gurdasani, M. Sandhu, P. Kellam, M. Hibberd, R. Newton, D. Whitby, I. Barroso

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Distinct genetic architectures and environmental factors associate with host response to the γ2-herpesvirus infections by Neneh Sallah, Wendell Miley, Nazzarena Labo, Tommy Carstensen, Segun Fatumo, Deepti Gurdasani, Martin O. Pollard, Alexander T. Dilthey, Alexander J. Mentzer, Vickie Marshall, Elena M. Cornejo Castro, Cristina Pomilla, Elizabeth H. Young, Gershim Asiki, Martin L. Hibberd, Manjinder Sandhu, Paul Kellam, Robert Newton, Denise Whitby, Inês Barroso

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Next-generation in situ hybridization approaches to define and quantify HIV and SIV reservoirs in tissue microenvironments by Claire Deleage, Chi N. Chan, Kathleen Busman-Sahay, Jacob D. Estes

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OA2-5 LB No evidence of ongoing replication in tissue compartments during combination antiretroviral therapy by G. Bozzi, S. Watters, F.R. Simonetti, E. Anderson, R. Gorelick, W. Shao, J. Bell, C. Rehm, R. Dewar, R. Yarchoan, T. Uldrick, F. Maldarelli

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RefCNV: Identification of Gene-Based Copy Number Variants Using Whole Exome Sequencing by Lun-Ching Chang, Biswajit Das, Chih-Jian Lih, Han Si, Corinne E. Camalier, Paul M. McGregor, Eric Polley

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Genetic and epigenetic intratumor heterogeneity impacts prognosis of lung adenocarcinoma by Xing Hua, Wei Zhao, Angela C. Pesatori, Dario Consonni, Neil E. Caporaso, Tongwu Zhang, Bin Zhu, Mingyi Wang, Kristine Jones, Belynda Hicks, Lei Song, Joshua Sampson, David C. Wedge, Jianxin Shi, Maria Teresa Landi

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