Leighs disease: powerhouse failure by Himanshu Dua, Radhika Mantry

Subjects: “…leigh disease…”
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Differential diagnosis of Acute Flaccid Paralysis in children: clinical case of Leigh disease by N. V. Skripchenko, A. A. Vilnits, N. V. Matyunina

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Leigh's Disease: The Acute Clinical Course of a Two-Year-Old Child with Subacute Necrotizing Encephalomyelopathy by Bettina Zinka, Andreas Buettner, Matthias Graw

“…On the basis of the characteristic neuropathological findings in combination with the age of the child, we had to take into consideration that the child might have died from subacute necrotizing encephalomyelopathy (Leigh's Disease) despite the untypical, fulminant clinical course.…”
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P021: Expansion of the phenotype of thiamine pyrophosphokinase deficiency: A treatable cause of Leigh disease, includes severe neuronopathic disease by Jennifer Harmon, Olivier Fortin, Jason Schroeder, Laura Tochen, Jamie Fraser

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How to mitigate neurological and cardiac decompensation in Leigh syndrome: Can nicotinamide riboside be an answer? by Alessandro Prigione, Carlo Viscomi

Subjects: “…Leigh disease…”
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The Newcastle Pediatric Mitochondrial Disease Scale: translation and cultural adaptation for use in Brazil by Gabriela Palhares Campolina-Sampaio, Laura Maria de Lima Belizário Facury Lasmar, Beatriz Silva Vilela Ribeiro, Juliana Gurgel Giannetti

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Evaluation of the Genetically Diagnosed Mitochondrial Disease Cases with Neuromuscular Involvement by Çağatay Günay, Cem Paketçi, Pınar Edem, Gamze Sarıkaya Uzan, Ayşe Semra Hız Kurul, Zümrüt Arslan Gülten, Pelin Teke Kısa, Nur Arslan, Uluç Yıs

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Leigh syndrome global patient registry: uniting patients and researchers worldwide by Sophia Zilber, Kasey Woleben, Simon C. Johnson, Carolina Fischinger Moura de Souza, Danielle Boyce, Kevin Freiert, Courtney Boggs, Souad Messahel, Melinda J. Burnworth, Titilola M. Afolabi, Saima Kayani

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Anesthetic Management of a Pediatric Patient with Leigh Syndrome by Ismail Serhat Kocamanoglu, Esra Sarihasan

“…Intensive care and breathing support for the patient with LS, under sedation with an analgesic combination during the early postoperative period, minimized the stress response due to pain after surgery. Keywords: Leigh Disease, Anesthesia, General, Monitoring, Physiologic, Intensive Care…”
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Reliability of MRI in detection and differentiation of acute neonatal/pediatric encephalopathy causes among neonatal/pediatric intensive care unit patients by Tamir A. Hassan, Nesreen Mohey

“…The final diagnosis of the study group patients were hypoxic ischemia injury (HII) in 39 patients (65%), metachromatic leukodystrophy in 6 patients (10%), biotin-thiamine-responsive basal ganglia disease (BTBGD) and Leigh disease each in 4 patients (6.7%), periventricular leukomalacia (PVL) in 3 patients (5%), and mitochondrial encephalopathy with lactic acidosis and stroke-like episodes syndrome (MELAS) and non-ketotic hyperglycinemia (NKH) each in 2 patients (3.3%). …”
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Mitochondrial complex I deficiency leads to the retardation of early embryonic development in Ndufs4 knockout mice by Mei Wang, Ya-Ping Huang, Han Wu, Ke Song, Cong Wan, A-Ni Chi, Ya-Mei Xiao, Xiao-Yang Zhao

“…In our study, we attempted to investigate embryonic development in Ndufs4 KO mice, which can be regarded as a Leigh disease model and were created through the CRISPR (clustered regularly interspaced short palindromic repeat) and Cas9 (CRISPR associated)-mediated genome editing system. …”
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