Leighs disease: powerhouse failure by Himanshu Dua, Radhika Mantry

Subjects: “…leigh disease…”
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Differential diagnosis of Acute Flaccid Paralysis in children: clinical case of Leigh disease by N. V. Skripchenko, A. A. Vilnits, N. V. Matyunina

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P021: Expansion of the phenotype of thiamine pyrophosphokinase deficiency: A treatable cause of Leigh disease, includes severe neuronopathic disease by Jennifer Harmon, Olivier Fortin, Jason Schroeder, Laura Tochen, Jamie Fraser

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How to mitigate neurological and cardiac decompensation in Leigh syndrome: Can nicotinamide riboside be an answer? by Alessandro Prigione, Carlo Viscomi

Subjects: “…Leigh disease…”
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The Newcastle Pediatric Mitochondrial Disease Scale: translation and cultural adaptation for use in Brazil by Gabriela Palhares Campolina-Sampaio, Laura Maria de Lima Belizário Facury Lasmar, Beatriz Silva Vilela Ribeiro, Juliana Gurgel Giannetti

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Leigh syndrome global patient registry: uniting patients and researchers worldwide by Sophia Zilber, Kasey Woleben, Simon C. Johnson, Carolina Fischinger Moura de Souza, Danielle Boyce, Kevin Freiert, Courtney Boggs, Souad Messahel, Melinda J. Burnworth, Titilola M. Afolabi, Saima Kayani

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Anesthetic Management of a Pediatric Patient with Leigh Syndrome by Ismail Serhat Kocamanoglu, Esra Sarihasan

“…Intensive care and breathing support for the patient with LS, under sedation with an analgesic combination during the early postoperative period, minimized the stress response due to pain after surgery. Keywords: Leigh Disease, Anesthesia, General, Monitoring, Physiologic, Intensive Care…”
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The Effects of a Ketogenic Diet on Patients with Dihydrolipoamide Dehydrogenase Deficiency by Orna Staretz-Chacham, Ben Pode-Shakked, Eyal Kristal, Smadar Yaala Abraham, Keren Porper, Ohad Wormser, Ilan Shelef, Yair Anikster

“…Inherited DLD-E3 deficiency, caused by the pathogenic variants in DLD, leads to variable presentations and courses of illness, ranging from myopathy, recurrent episodes of liver disease and vomiting, to Leigh disease and early death. Currently, there is no consensus on treatment guidelines, although one suggested solution is a ketogenic diet (KD). …”
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Mitochondrial complex I deficiency leads to the retardation of early embryonic development in Ndufs4 knockout mice by Mei Wang, Ya-Ping Huang, Han Wu, Ke Song, Cong Wan, A-Ni Chi, Ya-Mei Xiao, Xiao-Yang Zhao

“…In our study, we attempted to investigate embryonic development in Ndufs4 KO mice, which can be regarded as a Leigh disease model and were created through the CRISPR (clustered regularly interspaced short palindromic repeat) and Cas9 (CRISPR associated)-mediated genome editing system. …”
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