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Leighs disease: powerhouse failure
Published 2018-01-01Subjects: “…leigh disease…”
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Differential diagnosis of Acute Flaccid Paralysis in children: clinical case of Leigh disease
Published 2014-12-01Get full text
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How to mitigate neurological and cardiac decompensation in Leigh syndrome: Can nicotinamide riboside be an answer?
Published 2022-09-01Subjects: “…Leigh disease…”
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Leigh syndrome global patient registry: uniting patients and researchers worldwide
Published 2023-09-01Subjects: Get full text
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Anesthetic Management of a Pediatric Patient with Leigh Syndrome
Published 2013-03-01“…Intensive care and breathing support for the patient with LS, under sedation with an analgesic combination during the early postoperative period, minimized the stress response due to pain after surgery. Keywords: Leigh Disease, Anesthesia, General, Monitoring, Physiologic, Intensive Care…”
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The Effects of a Ketogenic Diet on Patients with Dihydrolipoamide Dehydrogenase Deficiency
Published 2021-10-01“…Inherited DLD-E3 deficiency, caused by the pathogenic variants in DLD, leads to variable presentations and courses of illness, ranging from myopathy, recurrent episodes of liver disease and vomiting, to Leigh disease and early death. Currently, there is no consensus on treatment guidelines, although one suggested solution is a ketogenic diet (KD). …”
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Mitochondrial complex I deficiency leads to the retardation of early embryonic development in Ndufs4 knockout mice
Published 2017-05-01“…In our study, we attempted to investigate embryonic development in Ndufs4 KO mice, which can be regarded as a Leigh disease model and were created through the CRISPR (clustered regularly interspaced short palindromic repeat) and Cas9 (CRISPR associated)-mediated genome editing system. …”
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