Construction of an El Tor Biovariant Vibrio cholerae Strain Capable of Type II Cholera Toxin Hyperproduction and Determining the Optimal Conditions for the Production of This Prote... by A. A. Goryaev, E. Yu. Shchelkanova, Yu. V. Lozovsky, I. V. Touchkov, N. I. Smirnova

“…A single clone with the highest cholera toxin biosynthesis levels (42.0-45.0 |xg/ml) was selected among the insertion mutants Km" Tox+and designated as KM234. …”
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Clinical Lymph Node Involvement as a Predictor for Cancer-Specific Survival in Patients with Penile Squamous Cell Cancer by Makoto Kawase, Kimiaki Takagi, Kei Kawada, Takashi Ishida, Masayuki Tomioka, Torai Enomoto, Shota Fujimoto, Tomoki Taniguchi, Hiroki Ito, Koji Kameyama, Toru Yamada, Kota Kawase, Daiki Kato, Manabu Takai, Koji Iinuma, Keita Nakane, Takuya Koie

“…Using the Kaplan–Meier method, the Eastern Cooperative Oncology Group performance status 0, serum albumin levels ≥4.2 g/dL, hemoglobin levels ≥13.2 g/dL, C-reactive protein levels <0.21 mg/dL, clinical T stage ≤2, clinically negative lymph node (LN) status, and tumor size <30 mm were associated with a significantly better CSS. …”
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Adolescents and reproductive health: Promoting healthy habits for reproductive well-being by Sri Sumaryani, Heni Purwaningsih

“…Prior to health education implementation, most students demonstrated low knowledge levels (52.6%), followed by moderate levels (42.3%), while a tiny proportion had high knowledge levels (5.1%). …”
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Enzyme Conditioning of Chicken Collagen and Taguchi Design of Experiments Enhancing the Yield and Quality of Prepared Gelatins by Pavel Mokrejš, Robert Gál, Jana Pavlačková

“…A Taguchi design with two process factors (extraction temperature and extraction time) was used at three levels (42, 46, and 50 °C; 20, 40, and 60 min) to optimize the processing of the MDCM by-product into gelatins. …”
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Rhodanine-Bridged Core-Expanded Naphthalene Diimide Derivatives for n-Type Semiconductors by Jiangao Li, Jing Li, Congwu Ge, Xike Gao

“…As a result, both T1 and T2 showed slightly lower lying LUMO energy levels (< − 4.2 eV) by ca. 0.1 eV and narrower optical band gaps (ca. 1.5 eV) by 0.5 eV compared to those of n-type organic semiconductor (OSC) NDI2DT-DTYM2.The solution-processed organic thin-film transistors based on T1 and T2 exhibited electron motilities in the range of 10−4–10−3 cm2 V−1 s−1, and the inverted perovskite solar cells constructed using T2 as electron transport materials provided a power conversion efficiency value of 8.82%. …”
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Neurosteroid [3α,5α]-3-hydroxy-pregnan-20-one enhances IL-10 production via endosomal TRIF-dependent TLR4 signaling pathway by Irina Balan, Adelina Grusca, Todd K. O’Buckley, A. Leslie Morrow, A. Leslie Morrow, A. Leslie Morrow

“…To determine the role of the TRIF-dependent TLR4 signaling pathway in IL-10 production, the downregulation of TRIF (−62.9 ± 28.2%) in RAW264.7 cells led to a reduction in IL-10 levels (−42.3 ± 8.4%). TRIF (−62.9 ± 28.2%) in RAW264.7 cells led to a reduction in IL-10 levels (−42.3 ± 8.4%) and 3α,5α-THP (1.0 µM) no longer restored the reduced IL-10 levels.ConclusionThe results demonstrate 3α,5α-THP enhancement of the endosomal TLR4-TRIF anti-inflammatory signals and elevations of IL-10 in male P rat brain that were not detected in female P rat brain. …”
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Comparison of empathy with patients between first-year and last-year medical students of Tehran University of Medical Sciences by Reyhane Hizomi Arani, Zohrehsadat Naji, Ali Moradi, Seyed Vahid Shariat, Sara Mirzamohamadi, Payman Salamati

“…Methods To assess the empathy levels, 42 first-year and an equal number of last-year medical students were randomly selected. …”
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Vitamin D Intake and Serum Levels in Pregnant and Postpartum Women by Laila Meija, Anna Piskurjova, Ksenija Nikolajeva, Olga Aizbalte, Roberta Rezgale, Aivars Lejnieks, Vinita Cauce

“…The median serum vitamin D concentration was 34.0 ng/mL, with pregnant women having higher levels (42.9 ng/mL) than postpartum women (31.8 ng/mL). …”
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The level of galectin-3 in the blood serum of patients with chronic hepatitis C by V. A. Kovalevа, N. S. Zhevnerova, T. V. Antonova

“…We evaluated the association between the content of galectin-3 in the blood and metabolic disorders, biochemical activity of hepatitis and fibrosis of the liver.Results: In patients with normal ALT levels (42% of the patients), the average level of galectin was 3.17 (1.23; 5.94) ng / ml. …”
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Intraoperative US-guided large volume ethanol injection for hepatocellular carcinoma greater than 4 cm by Ricardo Mondragón-Sánchez, Ana Lilia Garduño-López, Elvira Gómez-Gómez, Mauricio Frias-Mendivil, Alejandro Mondragón-Sánchez, Rigoberto Bernal-Maldonado

“…A significant reduction of AFP levels after treatment was observed (Initial 966 ng/dL, post treatment levels: 42 ng/dL) US and CT scan showed tumor necrosis. …”
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Perspectives of the Saudi medical students toward the impact of lockdowns on their physical activity level and lifestyle during the COVID-19 pandemic by Asma Alrushud, Dalyah Alamam, Muneera Almurdi, Ghaliah A. Dablan, Alanoud A. Alghamdi, Fatimah K. Almazyad, Malak A. Alhamdani, Khlood A. Alqarni, Hosam Alzahrani

“…During the lockdown and shift to online learning, the majority of participants experienced decreased PA levels, 42.4% experienced weight gain, and 53.6% reported a negative impact on their psychological status. …”
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Vegan diet as a possible cause of mental and physical disorders due to vitamin B12 deficiency in an adolescent patient by E. Gruber, S. Martic Biocina

“…Results Laboratory tests showed a deficiency of vitamin B12 (130 pmol/L) and 25-Hydroxy-Vitamin D(D3+D2) (47 nmol/l) and slightly elevated TSH levels (4,2x10-3 IU/L). These tests can explain the patient’s symptoms. …”
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Characteristics of Meningitis in Febrile Infants Aged ≤90 Days by Kyu Un Cho, Su Jeong You

“…Furthermore, there were normal C-reactive protein levels (42.9%) and no pleocytosis (20%) in some cases of bacterial meningitis. …”
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Roots and stems of Kadsura coccinea extract induced developmental toxicity in zebrafish embryos/larvae through apoptosis and oxidative stress by Zhongshang Xia, Erwei Hao, Zhangmei Chen, Mingzhe Zhang, Yanting Wei, Man Wei, Xiaotao Hou, Zhengcai Du, Jiagang Deng

“…Moreover, the decreased liver areas (25%) and fluorescence intensity (33%), increased ALT (37%) and AST levels (42%) were found in larvae treated with KCH (30 μg/mL). …”
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The Value of Laboratory Parameters for Anemia, Renal Function, Systemic Inflammation and Nutritional Status as Predictors for Outcome in Elderly Patients with Head-and-Neck Cancers by Alexander Rühle, Erik Haehl, Hélène David, Tobias Kalckreuth, Tanja Sprave, Raluca Stoian, Constantinos Zamboglou, Eleni Gkika, Andreas Knopf, Anca-Ligia Grosu, Nils Henrik Nicolay

“…In the univariate Cox regression analysis, hemoglobin ≤ 12 g/dL (HR = 1.536, <i>p</i> < 0.05), a GFR ≤ 60 mL/min/1.73 m² (HR = 1.537, <i>p</i> < 0.05), a CRP concentration > 5 mg/L (HR = 1.991, <i>p</i> < 0.001) and albumin levels ≤ 4.2 g/dL (HR = 2.916, <i>p</i> < 0.001) were significant risk factors for OS. …”
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The Racial Disparities in the Epidemic of Metabolic Syndrome With Increased Age: A Study From 28,049 Chinese and American Adults by Ruiying Zhang, Jie Sun, Chaofan Wang, Xiangtuo Wang, Pei Zhao, Yucong Yuan, Hu Ai, Qi Zhou

“…The two most prevalent components in Chinese subjects were reduced high-density lipoprotein cholesterol levels (42.0%) and elevated blood pressure (49.5%), and elevated triglyceride levels (36.3–49.5%) and abdominal obesity (55.8–55.9%) in Americans. …”
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ASSOCIATION BETWEEN HANDGRIP STRENGTH AND INFLAMMATION IN HEMODIALYSIS PATIENTS by Viviane O Leal, Milena B Stockler-Pinto, Julie C Lobo, Najla E Farage, Luiz A Anjos, Denise Mafra

“…According to the CRP levels, 42.4% of the HD patients presented inflammation (CRP > 0.3mg/dL). …”
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Prognostic significance of minimal residual disease detected by a simplified flow cytometric assay during remission induction chemotherapy in children with acute lymphoblastic leuk... by Kyung Nam Koh, Meerim Park, Bo Eun Kim, Ho Joon Im, Chan-Jeoung Park, Seongsoo Jang, Hyun Sook Chi, Jong Jin Seo

“…Seven patients with ≥1% leukemic cells on day 14 had a significantly lower relapse-free survival (RFS) compared to the 30 patients with lower levels (42.9% [18.7%] vs. 92.0% [5.4%], P=0.004). Stratification into 3 MRD groups (≥1%, 0.1-1%, and <0.1%) also showed a statistically significant difference in RFS (42.9% [18.7%] vs. 86.9% [8.7%] vs. 100%, P=0.013). …”
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Effect of individualised nutritional intervention on the postpartum nutritional status of patients with gestational diabetes mellitus and the growth and development of their offspr... by Jie Tan, Liangliang Huo, Xia Qian, Xiaohua Wang

“…Individualised nutritional intervention could improve blood glucose levels 42 days after childbirth and reduce macrosomia incidence in pregnant women with GDM.Impact statement What is already known on this subject? …”
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Perceived change in physical activity levels and mental health during COVID-19: Findings among adult twin pairs. by Glen E Duncan, Ally R Avery, Edmund Seto, Siny Tsang

“…<h4>Results</h4>More twin pairs reported a decrease in physical activity levels (42%) than those reporting no change (31%) or increased physical activity levels (27%). …”
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