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    Cerebral Microstructural and Microvascular Changes in Non-Neuropsychiatric Systemic Lupus Erythematosus: A Study Using Diffusion Kurtosis Imaging and 3D Pseudo-Continuous Arterial... by Wang X, Huang L, Guo W, Tang L, Wu A, Wu P, Zhao X, Lin Q, Yu L

    Published 2023-11-01
    “…Xiaojuan Wang,1,* Lingling Huang,1,* Wenbin Guo,2,* Langlang Tang,1 Aiyu Wu,3 Peng Wu,4 Xiance Zhao,4 Qi Lin,1 Lian Yu3 1Department of Radiology, Longyan First Affiliated Hospital of Fujian Medical University, Longyan, Fujian, 364000, People’s Republic of China; 2Department of Pathology, Pingtan Comprehensive Experimental Area Hospital, Fuzhou, Fujian, 350400, People’s Republic of China; 3Department of Rheumatology, Longyan First Affiliated Hospital of Fujian Medical University, Longyan, Fujian, 364000, People’s Republic of China; 4Philips Healthcare, Shanghai, 200000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Qi Lin, Department of Radiology, Longyan First Affiliated Hospital of Fujian Medical University, No. 105, Jiu Yi North Road, Xin Luo District, Longyan City, 364000, People’s Republic of China, Tel + 86 13950881931, Email linqii8m@126.com Lian Yu, Department of Rheumatology, Longyan First Affiliated Hospital of Fujian Medical University, No. 105, Jiu Yi North Road, Xin Luo District, Longyan City, 364000, People’s Republic of China, Email yulianian@126.comPurpose: The purpose of this study was to observe cerebral microstructure and microcirculation features, as well as changes in white matter (WM) and gray matter (GM) among patients with non-neuropsychiatric systemic lupus erythematosus (non-NPSLE).Methods: We compared 36 female patients with non-NPSLE and 20 age- and gender-matched healthy controls (HCs) who underwent 3.0T MRI imaging with diffusion kurtosis imaging (DKI) and 3D pseudo-continuous Arterial Spin Labeling (pCASL). …”
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