Anti-SOD1 Nanobodies That Stabilize Misfolded SOD1 Proteins Also Promote Neurite Outgrowth in Mutant SOD1 Human Neurons by Meenakshi Sundaram Kumar, Megan E. Fowler-Magaw, Daniel Kulick, Sivakumar Boopathy, Del Hayden Gadd, Melissa Rotunno, Catherine Douthwright, Diane Golebiowski, Issa Yusuf, Zuoshang Xu, Robert H. Brown, Miguel Sena-Esteves, Alison L. O'Neil, Daryl A. Bosco

Subjects: “…amyotrophic lateral sclerosis (ALS) (Lou Gehrig disease)…”
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STEPHEN HAWKING : AN UNFETTERED MIND / by Ferguson, Kitty, author 581054

“…Yet while his mind roams to the farthest corners of reality, his body has become increasingly trapped by the advance of Lou Gehrig's disease, which has bound him to a wheelchair, without speech or movement except for a few facial muscles. …”

Emerging role of senescent microglia in brain aging-related neurodegenerative diseases by Chan Rim, Min-Jung You, Minyeop Nahm, Min-Soo Kwon

“…Abstract Brain aging is a recognized risk factor for neurodegenerative diseases like Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS, Lou Gehrig's disease), but the intricate interplay between brain aging and the pathogenesis of these conditions remains inadequately understood. …”
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