Study protocol: a randomised controlled proof-of-concept real-world study – does maximising time in range using hybrid closed loop insulin delivery and a low carbohydrate diet restore the glucagon response to hypoglycaemia in adults with type 1 diabetes? by Shareen Forbes, Faye Baxter, Nicola Baillie

“…However, post-prandial glycaemic excursions are still evident. Consuming a low carbohydrate diet (LCD) may minimise these excursions.Methods and analysis This feasibility study will assess if maximising TIR (glucose ≥3.9 mmol/L≤10 mmol/L) using HCL systems plus an LCD (defined here as <130 g carbohydrate/day) for >8 months, restores the glucagon response to insulin-induced hypoglycaemia. …”
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Las dietas cetogénicas: fundamentos y eficacia para la pérdida de peso by Joaquín Pérez-Guisado

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Ketogenic diets composed of long-chain and medium-chain fatty acids induce cardiac fibrosis in mice by Felix Sternberg, Christina Sternberg, Andreas Dunkel, Taraneh Beikbaghban, András Gregor, Aleksander Szarzynski, Veronika Somoza, Ingrid Walter, Kalina Duszka, Barbara Kofler, Elena E. Pohl

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The role of diet therapy in insulin resistance in women with polycystic ovary syndrome by H.B. Semenyna, T.V. Fartushok, N.V. Fartushok, N.Ya. Dumanchuk, O.M. Yurchyshyn

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Predictors of weight loss in patients with obesity treated with a Very Low-Calorie Ketogenic Diet by Ilaria Ernesti, Francesco Baratta, Mikiko Watanabe, Renata Risi, Elisabetta Camajani, Agnese Persichetti, Dario Tuccinardi, Stefania Mariani, Carla Lubrano, Alfredo Genco, Giovanni Spera, Lucio Gnessi, Sabrina Basciani

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The modulation of carbohydrate intake and intermittent fasting in obese Saudi women: a pilot study by Muneerah H. Al-jammaz, Abdulrahman Al-kalifah, Nawal Abdullah Al-bader, Maha H. Al-hussain

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The application of carbohydrate-reduction in general practice: A medical audit by Marcus A. Hawkins, Caryn Zinn, Christine Delon

Subjects: “…low-carbohydrate diets…”
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Las dietas cetogénicas: fundamentos y eficacia para la pérdida de peso by Joaquín Pérez-Guisado

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Blood glucose control and glomerular capillary basement membrane thickening in experimental diabetes. by Fox, C, Darby, S, Ireland, J, Sönksen, P

“…Diabetic rats were randomly allocated to different groups, either receiving no treatment or treated with a low carbohydrate diet or insulin, or both. Control rats were randomly allocated to a normal or low carbohydrate diet. …”

A high-fat diet impairs cardiac high-energy phosphate metabolism and cognitive function in healthy human subjects. by Holloway, C, Cochlin, L, Emmanuel, Y, Murray, A, Codreanu, I, Edwards, L, Szmigielski, C, Tyler, D, Knight, N, Saxby, B, Lambert, B, Thompson, C, Neubauer, S, Clarke, K

“…BACKGROUND: High-fat, low-carbohydrate diets are widely used for weight reduction, but they may also have detrimental effects via increased circulating free fatty acid concentrations. …”

Dietary composition modulates brain mass and solubilizable Aβ levels in a mouse model of aggressive Alzheimer's amyloid pathology by Buxbaum Joseph D, Martins Ralph N, Hyslop Peter, Westaway David, Fraser Paul, Ho Lap, Schmeidler James, Brautigam Hannah, Thomas Carlos, Pedrini Steve, Pasinetti Giulio M, Dickstein Dara L, Hof Patrick R, Ehrlich Michelle E, Gandy Sam

“…Unexpectedly, brains of mice fed a high protein/low carbohydrate diet were 5% lower in weight than brains from all other mice. …”
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The Effect of the Ketogenic Diet on the Therapy of Neurodegenerative Diseases and Its Impact on Improving Cognitive Functions by Klaudia Grochowska, Anna Przeliorz

“…The ketogenic diet (KD) is a high-fat and low-carbohydrate diet with controlled amounts of protein. …”
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Exercise prevents the accumulation of triglyceride-rich lipoproteins and their remnants seen when changing to a high-carbohydrate diet. by Koutsari, C, Karpe, F, Humphreys, S, Frayn, K, Hardman, A

“…Plasma triglycerides were higher after the high-carbohydrate diet than after the low-carbohydrate diet: fasting, 1.58+/-0.19 versus 0.96+/-0.12 mmol/L, respectively; 6-hour postprandial area under concentration versus time curve, 13.74+/-1.57 versus 10.12+/-1.15 (mmol/L)xhour, respectively (both P<0.01). …”

Ketogenic diets and physical performance by Phinney SD

“…Impaired physical performance is a common but not obligate result of a low carbohydrate diet. Lessons from traditional Inuit culture indicate that time for adaptation, optimized sodium and potassium nutriture, and constraint of protein to 15-25 % of daily energy expenditure allow unimpaired endurance performance despite nutritional ketosis.…”
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Ketogenic diets and physical performance by Phinney Stephen D

“…<p>Abstract</p> <p>Impaired physical performance is a common but not obligate result of a low carbohydrate diet. Lessons from traditional Inuit culture indicate that time for adaptation, optimized sodium and potassium nutriture, and constraint of protein to 15–25 % of daily energy expenditure allow unimpaired endurance performance despite nutritional ketosis.…”
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Sex-specific differences in metabolic hormone and adipose tissue dynamics induced by moderate low-carbohydrate and ketogenic diet by Ilya Smolensky, Kilian Zajac-Bakri, Timothy Sasha Odermatt, Catherine Brégère, John F. Cryan, Raphael Guzman, Katharina Timper, Dragos Inta

“…Abstract Low-carbohydrates diets are increasingly used to treat obesity and metabolic disorders. …”
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Increasing plasma free fatty acids in healthy subjects induces aortic distensibility changes seen in obesity. by Rider, O, Holloway, C, Emmanuel, Y, Bloch, E, Clarke, K, Neubauer, S

“…In 2 further normal-weight groups, AD was recorded before and after elevation of FFA levels with intralipid infusion (by +535%, n=9) and a 5-day high-fat, low-carbohydrate diet (by +48%, n=14). CONCLUSIONS: Both intralipid infusion and a low-carbohydrate diet resulted in reduced abdominal AD (infusion -22%, diet -28%; both P&lt;0.05), reproducing the distal pattern AD reduction seen in obesity. …”

A sportomics strategy to analyze the ability of arginine to modulate both ammonia and lymphocyte levels in blood after high-intensity exercise by Gonçalves Luis, Bessa Artur, Freitas-Dias Ricardo, Luzes Rafael, Werneck-de-Castro João Pedro, Bassini Adriana, Cameron Luis-Claudio

“…The subjects followed a low-carbohydrate diet for four days before the trials and received either arginine supplementation (100 mg·kg^-1 of body mass·day^-1) or a placebo. …”
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Ketogenic diet by Tina Bregant, Andreja Širca Čampa, Neža Zupančič, David Neubauer

“…Background The ketogenic diet is a high fat, adequate protein, low carbohydrate diet. It has been used in the treatment of intractable childhood epilepsy, difficult-to-control seizures in adults, GLUT1 deficiency syndrome and PDH deficiency. conclusions This review traces a history of ketogenic diet, reviews its uses and side effects, and discusses possible alternatives and the diet’s possible mechanisms of action. …”
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Third Exposure to a Reduced Carbohydrate Meal Lowers Evening Postprandial Insulin and GIP Responses and HOMA-IR Estimate of Insulin Resistance. by Po-Ju Lin, Katarina T Borer

“…The parallel timing and magnitude of postprandial insulin and GIP changes suggest their dependence on a delayed intestinal adaptation to a low-carbohydrate diet. Pre-meal exercise exacerbated glucose intolerance with both diets most likely due to impairment of insulin signaling by pre-meal elevation of FFAs.…”
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