ChIP-seq profiling of the active chromatin marker H3K4me3 and PPARγ, CEBPα and LXR target genes in human SGBS adipocytes by Mafalda Galhardo, Lasse Sinkkonen, Philipp Berninger, Jake Lin, Thomas Sauter, Merja Heinäniemi

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The role of phages for microdiverse bacterial communities in proglacial stream biofilms by Hannes Peter, Grégoire Michoud, Susheel Bhanu Busi, Susheel Bhanu Busi, Tom J. Battin

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Sensor-Based Quantification of MDS-UPDRS III Subitems in Parkinson’s Disease Using Machine Learning by Rene Peter Bremm, Lukas Pavelka, Maria Moscardo Garcia, Laurent Mombaerts, Rejko Krüger, Frank Hertel

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Graft-derived neurons and bystander effects are maintained for six months after human iPSC-derived NESC transplantation in mice’s cerebella by Liliana S. Mendonça, Daniel Henriques, Vanessa Fernandes, Ricardo Moreira, João Brás, Sónia Duarte, Jens C. Schwamborn, Luís Pereira de Almeida

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Human Dopaminergic Neurons Lacking PINK1 Exhibit Disrupted Dopamine Metabolism Related to Vitamin B6 Co-Factors by Christine Bus, Laimdota Zizmare, Marita Feldkaemper, Sven Geisler, Maria Zarani, Anna Schaedler, Franziska Klose, Jakob Admard, Craig J. Mageean, Giuseppe Arena, Petra Fallier-Becker, Aslihan Ugun-Klusek, Klaudia K. Maruszczak, Konstantina Kapolou, Benjamin Schmid, Doron Rapaport, Marius Ueffing, Nicolas Casadei, Rejko Krüger, Thomas Gasser, Daniela M. Vogt Weisenhorn, Philipp J. Kahle, Christoph Trautwein, Christian J. Gloeckner, Julia C. Fitzgerald

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Development and Validation of a Prognostic Risk Score System for COVID-19 Inpatients: A Multi-Center Retrospective Study in China by Ye Yuan, Chuan Sun, Xiuchuan Tang, Cheng Cheng, Laurent Mombaerts, Maolin Wang, Tao Hu, Chenyu Sun, Yuqi Guo, Xiuting Li, Hui Xu, Tongxin Ren, Yang Xiao, Yaru Xiao, Hongling Zhu, Honghan Wu, Kezhi Li, Chuming Chen, Yingxia Liu, Zhichao Liang, Zhiguo Cao, Hai-Tao Zhang, Ioannis Ch. Paschaldis, Quanying Liu, Jorge Goncalves, Qiang Zhong, Li Yan

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Systems genetics approaches for understanding complex traits with relevance for human disease by Hooman Allayee, Charles R Farber, Marcus M Seldin, Evan Graehl Williams, David E James, Aldons J Lusis

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Data-driven multiscale modeling reveals the role of metabolic coupling for the spatio-temporal growth dynamics of yeast colonies by Jukka Intosalmi, Adrian C. Scott, Michelle Hays, Nicholas Flann, Olli Yli-Harja, Harri Lähdesmäki, Aimée M. Dudley, Alexander Skupin

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Mitochondria preserve an autarkic one-carbon cycle to confer growth-independent cancer cell migration and metastasis by Nicole Kiweler, Catherine Delbrouck, Vitaly I. Pozdeev, Laura Neises, Leticia Soriano-Baguet, Kim Eiden, Feng Xian, Mohaned Benzarti, Lara Haase, Eric Koncina, Maryse Schmoetten, Christian Jaeger, Muhammad Zaeem Noman, Alexei Vazquez, Bassam Janji, Gunnar Dittmar, Dirk Brenner, Elisabeth Letellier, Johannes Meiser

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Longitudinal analysis of the faecal microbiome in pigs fed Cyberlindnera jadinii yeast as a protein source during the weanling period followed by a rapeseed- and faba bean-based gr... by Stanislav Iakhno, Francesco Delogu, Özgün C. O. Umu, Nils P. Kjos, Ingrid M. Håkenåsen, Liv T. Mydland, Margareth Øverland, Henning Sørum

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How can data visualization support interdisciplinary research? LuxTIME: studying historical exposomics in Belval by Dagny Aurich, Aida Horaniet Ibañez

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Prediction and verification of glycosyltransferase activity by bioinformatics analysis and protein engineering by Dietlind L. Gerloff, Elena I. Ilina, Camille Cialini, Uxue Mata Salcedo, Michel Mittelbronn, Tanja Müller

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Successes and Hurdles in Stem Cells Application and Production for Brain Transplantation by Daniel Henriques, Daniel Henriques, Ricardo Moreira, Ricardo Moreira, Jens Schwamborn, Luís Pereira de Almeida, Luís Pereira de Almeida, Luís Pereira de Almeida, Liliana S. Mendonça, Liliana S. Mendonça

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The role of peripheral inflammatory insults in Alzheimer’s disease: a review and research roadmap by Keenan A. Walker, Lydia M. Le Page, Niccolò Terrando, Michael R. Duggan, Michael T. Heneka, Brianne M. Bettcher

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Systems toxicology of complex wood combustion aerosol reveals gaseous carbonyl compounds as critical constituents by Marco Dilger, Olivier Armant, Larissa Ramme, Sonja Mülhopt, Sean C. Sapcariu, Christoph Schlager, Elena Dilger, Ahmed Reda, Jürgen Orasche, Jürgen Schnelle-Kreis, Thomas M. Conlon, Ali Önder Yildirim, Andrea Hartwig, Ralf Zimmermann, Karsten Hiller, Silvia Diabaté, Hanns-Rudolf Paur, Carsten Weiss

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Regulation of Fn14 Receptor and NF-κB Underlies Inflammation in Meniere’s Disease by Lidia Frejo, Teresa Requena, Satoshi Okawa, Alvaro Gallego-Martinez, Manuel Martinez-Bueno, Ismael Aran, Angel Batuecas-Caletrio, Jesus Benitez-Rosario, Juan M. Espinosa-Sanchez, Juan M. Espinosa-Sanchez, Jesus José Fraile-Rodrigo, Ana María García-Arumi, Rocío González-Aguado, Pedro Marques, Eduardo Martin-Sanz, Nicolas Perez-Fernandez, Paz Pérez-Vázquez, Herminio Perez-Garrigues, Sofía Santos-Perez, Andres Soto-Varela, Maria C. Tapia, Gabriel Trinidad-Ruiz, Antonio del Sol, Marta E. Alarcon Riquelme, Marta E. Alarcon Riquelme, Jose A. Lopez-Escamez, Jose A. Lopez-Escamez, Jose A. Lopez-Escamez

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Loss-of-function variants in the KCNQ5 gene are implicated in genetic generalized epilepsies by Johanna Krüger, Julian Schubert, Josua Kegele, Audrey Labalme, Miaomiao Mao, Jacqueline Heighway, Guiscard Seebohm, Pu Yan, Mahmoud Koko, Kezban Aslan-Kara, Hande Caglayan, Bernhard J. Steinhoff, Yvonne G. Weber, Pascale Keo-Kosal, Samuel F. Berkovic, Michael S. Hildebrand, Steven Petrou, Roland Krause, Patrick May, Gaetan Lesca, Snezana Maljevic, Holger Lerche

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LIPAD (LRRK2/Luebeck International Parkinson's Disease) Study Protocol: Deep Phenotyping of an International Genetic Cohort by Tatiana Usnich, Eva-Juliane Vollstedt, Nathalie Schell, Volha Skrahina, Xenia Bogdanovic, Hanaa Gaber, Toni M. Förster, Andreas Heuer, Natalia Koleva-Alazeh, Ilona Csoti, Ayse Nazli Basak, Sibel Ertan, Gencer Genc, Peter Bauer, Katja Lohmann, Anne Grünewald, Emma L. Schymanski, Joanne Trinh, Susen Schaake, Daniela Berg, Doreen Gruber, Stuart H. Isaacson, Andrea A. Kühn, Brit Mollenhauer, David J. Pedrosa, Kathrin Reetz, Esther M. Sammler, Enza Maria Valente, Franco Valzania, Jens Volkmann, Simone Zittel, Norbert Brüggemann, Norbert Brüggemann, Meike Kasten, Meike Kasten, Arndt Rolfs, Christine Klein, The LIPAD Study Group

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From Research to Diagnostic Application of Raman Spectroscopy in Neurosciences: Past and Perspectives by Gilbert Georg Klamminger, Katrin Frauenknecht, Michel Mittelbronn, Felix Bruno Kleine Borgmann

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Metabolic modelling-based in silico drug target prediction identifies six novel repurposable drugs for melanoma by Tamara Bintener, Maria Pires Pacheco, Demetra Philippidou, Christiane Margue, Ali Kishk, Greta Del Mistro, Luca Di Leo, Maria Moscardó Garcia, Rashi Halder, Lasse Sinkkonen, Daniela De Zio, Stephanie Kreis, Dagmar Kulms, Thomas Sauter

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